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Long term antidepressant use in a cohort of older people

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dc.contributor.author O'Neill, Aoife
dc.contributor.author McFarland, John
dc.contributor.author Kelly, Dervla
dc.date.accessioned 2021-03-22T15:09:58Z
dc.date.issued 2021
dc.identifier.uri http://hdl.handle.net/10344/9900
dc.description peer-reviewed en_US
dc.description The full text of this article will not be available in the ULIR until embargo expires on the 16/02/2022
dc.description.abstract Objectives: Depression is the most common mental health problem in older adults and untreated is associated with significant burden of illness for patients. This study aimed to examine longitudinal patterns of antidepressant use in older adults and determine which factors were associated with changes in use. Methods: Adults aged 50 and over, from the Irish Longitudinal Study on Ageing, who participated at any one of the four TILDA waves (n = 8,175) were included in the analysis. Repeated measures latent class analysis (RMLCA) is the model-based approach we used to identify underlying subgroups in a population. Results: We found antidepressant use ranged from 6% to 10%, over a 6-year period. RMLCA identified three distinct classes of anti-depressant use. Notably, 6% of older adults were categorised in a ‘long-term antidepressant use’ class, with consistent use across all four waves, and 6% were categorised in an ‘Intermittent/ Developing Use’ class. We found long-term antidepressant use to be a characteristic of older adults with chronic conditions at baseline of study and striking low uptake of psychological and psychiatric services. Conclusions: These findings provide evidence of the complex presentations of depression with comorbidities in long-term antidepressant users. While prolonged use of antidepressants in an older cohort is often rationalised due to recurrent depression and comorbidities, this study suggests little deprescribing of antidepressants and a need for greater access and provision of psychological services tailored to later life seem necessary improve management of this condition. en_US
dc.language.iso eng en_US
dc.publisher Wiley and Sons Ltd en_US
dc.relation.ispartofseries International Journal of Geriatric Psychiatry;
dc.relation.uri https://doi.org/10.1002/gps.5518
dc.rights This is the peer reviewed author version of the following article: Long term antidepressant use in a cohort of older people, which has been published in final form at https://doi.org/10.1002/gps.5518 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. http://olabout.wiley.com/WileyCDA/Section/id-828039.html#terms en_US
dc.subject antidepressant prescribing en_US
dc.subject longitudinal cohort en_US
dc.subject long term antidepressant use en_US
dc.title Long term antidepressant use in a cohort of older people en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1002/gps.5518
dc.date.embargoEndDate 2022-02-16
dc.embargo.terms 2022-02-16 en_US
dc.rights.accessrights info:eu-repo/semantics/embargoedAccess en_US


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