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Scaffold fabrication technologies and structure/function properties in bone tissue engineering

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dc.contributor.author Collins, Maurice N.
dc.contributor.author Ren, Guang
dc.contributor.author Young, Kieran
dc.contributor.author Pina, S.
dc.contributor.author Reis, Rui L.
dc.contributor.author Oliveira, J. Miguel
dc.date.accessioned 2021-03-19T10:03:40Z
dc.date.available 2021-03-19T10:03:40Z
dc.date.issued 2021
dc.identifier.uri http://hdl.handle.net/10344/9896
dc.description peer-reviewed en_US
dc.description.abstract Bone tissue engineering (BTE) is a rapidly growing field aiming to create a bio functional tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has become evident that scaffold fabrication techniques are very important in dictating the final structural, mechanical properties, and biological response of the implanted biomaterials. A comprehensive review of the current accomplishments on scaffold fabrication techniques, their structure, and function properties for BTE is provided herein. Different types of biomaterials ranging from inorganic biomaterials to natural and synthetic polymers and related composites for scaffold processing are presented. Emergent scaffolding techniques such as electrospinning, freeze-drying, bioprinting, and decellularization are also discussed. Strategies to improve vascularization potential and immunomodulation, which is considered a grand challenge in BTE scaffolding, are also presented. en_US
dc.language.iso eng en_US
dc.publisher Wiley en_US
dc.relation JICAM/0001/2 en_US
dc.relation.ispartofseries Advanced Functional Materials;2010609
dc.subject Bone tissue engineering en_US
dc.subject vascularization en_US
dc.title Scaffold fabrication technologies and structure/function properties in bone tissue engineering en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.contributor.sponsor Portuguese Foundation for Science and Technology en_US
dc.relation.projectid IF/01285/2015 en_US
dc.relation.projectid CEECIND/03673/2017 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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