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Dynamic contrast enhanced computed tomography: a precise technique for identifying and localising pancreatic necrosis

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dc.contributor.author Larvin, Michael
dc.contributor.author Chalmers, Alan G.
dc.contributor.author McMahon, Michael J.
dc.date.accessioned 2021-03-03T15:27:57Z
dc.date.available 2021-03-03T15:27:57Z
dc.date.issued 1990
dc.identifier.issn 0959-8138
dc.identifier.uri http://hdl.handle.net/10344/9843
dc.description peer-reviewed en_US
dc.description.abstract Objective-To evaluate dynamic contrast enhanced computed tomography for detecting and localising pancreatic necrosis in acute pancreatitis. Design-Prospective evaluation with blind reporting of scans. Setting-Single teaching hospital. Patients-60 Consecutive patients with acute pancreatitis suspected to have pancreatic necrosis because of major organ system failure (13); slow recovery five to seven days after admission with raised scores on the acute physiological and chronic health evaluation (APACHE-II) system (27); or findings on previous ultrasonography or computed tomography (20). Main outcome measure-Pancreatic necrosis proved histologically-that is, >30 g necrotic tissue debrided at laparotomy (for life threatening sepsis or peritonitis) or necropsy. Results-Dynamic computed tomography correctly localised pancreatic necrosis in 11 patients (confirmed at laparotomy in nine and at necropsy in two). Of nine patients with low enhancement of peripancreatic tissues alone, eight recovered after conservative management; necropsy confirmed viable pancreas and necrosis of peripancreatic fat in one patient. Of 40 patients with normal contrast enhancement, none required laparotomy to debride pancreatic necrosis. Conclusion-Dynamic contrast enhanced computed tomography seems to be a safe and accurate method of identifying and localising pancreatic and peripancreatic necrosis, which cannot be predicted accurately by conventional imaging techniques. en_US
dc.language.iso eng en_US
dc.publisher BMJ Publishing Group en_US
dc.relation.ispartofseries BMJ;300, pp.1425-1428
dc.relation.uri http://www.ncbi.nlm.nih.gov/pubmed/2379000
dc.subject pancreatic necrosis en_US
dc.title Dynamic contrast enhanced computed tomography: a precise technique for identifying and localising pancreatic necrosis en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.date.updated 2021-03-03T15:23:01Z
dc.description.version PUBLISHED
dc.identifier.doi 10.1136/bmj.300.6737.1425
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1435725
dc.internal.copyrightchecked Yes
dc.identifier.journaltitle BMJ
dc.description.status peer-reviewed


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