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Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants

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dc.contributor.author Mutambudzi, Miriam
dc.contributor.author Niedzwiedz, Claire L.
dc.contributor.author Macdonald, Ewan Beaton
dc.contributor.author Leyland, Alastair
dc.contributor.author Mair, Frances
dc.contributor.author Anderson, Jana J.
dc.contributor.author Celis-Morales, Carlos A.
dc.contributor.author Cleland, John G.F.
dc.contributor.author Forbes, John F.
dc.contributor.author Gill, Jason M.R.
dc.contributor.author Hastie, Claire E.
dc.contributor.author Ho, Frederick K.
dc.contributor.author Jani, Bhautesh
dc.contributor.author Mackay, Daniel F.
dc.contributor.author Nicholl, Barbara
dc.contributor.author O'Donnell, Catherine A.
dc.contributor.author Sattar, Naveed
dc.contributor.author Welsh, Paul
dc.contributor.author Pell, Jill P.
dc.contributor.author Katikireddi, Srinivasa Vittal
dc.contributor.author Demou, Evangelia
dc.date.accessioned 2021-01-19T14:47:28Z
dc.date.available 2021-01-19T14:47:28Z
dc.date.issued 2020
dc.identifier.uri http://hdl.handle.net/10344/9624
dc.description peer-reviewed en_US
dc.description.abstract Objectives To investigate severe COVID-19 risk by occupational group. Methods Baseline UK Biobank data (2006–10) for England were linked to SARS-CoV-2 test results from Public Health England (16 March to 26 July 2020). Included participants were employed or self-employed at baseline, alive and aged <65 years in 2020. Poisson regression models were adjusted sequentially for baseline demographic, socioeconomic, work-related, health, and lifestyle-related risk factors to assess risk ratios (RRs) for testing positive in hospital or death due to COVID-19 by three occupational classification schemes (including Standard Occupation Classification (SOC) 2000). Results Of 120 075 participants, 271 had severe COVID-19. Relative to non-essential workers, healthcare workers (RR 7.43, 95% CI 5.52 to 10.00), social and education workers (RR 1.84, 95% CI 1.21 to 2.82) and other essential workers (RR 1.60, 95% CI 1.05 to 2.45) had a higher risk of severe COVID-19. Using more detailed groupings, medical support staff (RR 8.70, 95% CI 4.87 to 15.55), social care (RR 2.46, 95% CI 1.47 to 4.14) and transport workers (RR 2.20, 95% CI 1.21 to 4.00) had the highest risk within the broader groups. Compared with white non-essential workers, non-white non-essential workers had a higher risk (RR 3.27, 95% CI 1.90 to 5.62) and non-white essential workers had the highest risk (RR 8.34, 95% CI 5.17 to 13.47). Using SOC 2000 major groups, associate professional and technical occupations, personal service occupations and plant and machine operatives had a higher risk, compared with managers and senior officials. Conclusions Essential workers have a higher risk of severe COVID-19. These findings underscore the need for national and organisational policies and practices that protect and support workers with an elevated risk of severe COVID-19. en_US
dc.language.iso eng en_US
dc.publisher BMJ Publishing Group en_US
dc.relation.ispartofseries Occupational and Environmental Medicine;
dc.relation.uri http://dx.doi.org/10.1136/oemed-2020-106731
dc.subject Covid-19 en_US
dc.title Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1136/oemed-2020-106731
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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