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Proposed hypothesis and rationale for association between mastitis and breast cancer

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Show simple item record Nolan, Joanne Dunne, Suzanne S. Mustafa, Wed Sivananthan, Laxsanaa Kiely, Patrick A. Dunne, Colum P. 2020-07-14T11:08:30Z 2020-07-14T11:08:30Z 2020
dc.description peer-reviewed en_US
dc.description.abstract Breast cancer is amongst the most common forms of cancer, is predominantly a woman’s illness, and is the most frequently reported invasive cancer in women worldwide (Bray et al., 2018). Varying risk factors have been identified, including genetics, family history, lifestyle, age and the use of hormone replacement therapy. Mastitis, also predominantly a woman’s illness, is an inflammatory condition of the breast that, despite being an inflammation-related condition, is not currently considered a risk factor for breast cancer. This appears counterintuitive as epidemiological studies have identified chronic inflammation as a contributor to cancer risk, for example in gastric, oesophageal and colon cancers (Lin et al., 2016; Qadri et al., 2014; Principe et al., 2017). Previous reports have focused on women hospitalised for mastitis, and most commonly on puerperal mastitis, perhaps underestimating the relationship between breast cancer and non-lactational mastitis. Our hypothesis, based on systematic review, suggests that a longitudinal study of this disease, affecting women predominantly, is warranted en_US
dc.language.iso eng en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Medical Hypotheses;144, 110057
dc.subject Breast cancer en_US
dc.subject Mastitis en_US
dc.title Proposed hypothesis and rationale for association between mastitis and breast cancer en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1016/j.mehy.2020.110057
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US

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