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Novel inorganic scintillating detectors and their applications in small animal irradiators: measurements and Monte Carlo simulations

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dc.contributor.author Byrne, Kevin
dc.contributor.author Alharbi, Majed
dc.contributor.author O'Keeffe, Sinéad
dc.contributor.author Kleefeld, Christoph
dc.contributor.author Bazalova-Carter, Magdalena
dc.contributor.author Foley, Mark
dc.date.accessioned 2020-04-08T12:52:29Z
dc.date.available 2020-04-08T12:52:29Z
dc.date.issued 2020
dc.identifier.uri http://hdl.handle.net/10344/8707
dc.description peer-reviewed en_US
dc.description.abstract In the field of radiation therapy, optical fiber dosimeters (OFD) offer several advantages over conventional dosimeters for real-time dosimetry. Their sensing tips can be small in size affording them the potential for high spatial resolution capabilities. In previous work, a novel inorganic scintillating detector (ISD) based on Gadolinium Oxysulfide (gadox) was fabricated for in vivo optical fiber dosimetry of conformal small animal irradiators. The performance of this detector was evaluated for 40 and 80 kVp imaging beams and the 220 kVp therapy beam of the Small Animal Research Platform (SARRP). The purpose of this study was to use a validated Monte Carlo (MC) model of the SARRP to investigate (i) dose absorption in the ISD active volume and (ii) dose perturbation by the inorganic scintillating phosphor volume. A comparison was also drawn between the perturbation by the gadox phosphor and a ZnS-based phosphor. The gadox-based detector was seen to cause high levels of dose perturbation in the radiation field, leaving significant dose shadows in the irradiated media. The use of ZnS:Ag phosphor reduces the perturbations with just over half as much dose absorbed relative to the gadox phosphor. An optimized ISD design which utilizes the higher light yield of the less perturbing ZnS:Ag phosphor to allow for a smaller high-density active volume, and significantly mitigating kV dose perturbation, has been proposed. en_US
dc.language.iso eng en_US
dc.publisher SPIE: The International Society for Optics and Phontonics en_US
dc.relation.ispartofseries Proc. SPIE 11354, Optical Sensing and Detection VI;113540U
dc.relation.uri http://dx.doi.org/ 10.1117/12.2551148
dc.rights Copyright 2020 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited en_US
dc.subject inorganic scintillating detector en_US
dc.subject Monte Carlo en_US
dc.subject optical fiber dosimeter en_US
dc.subject scintillator en_US
dc.subject small animal irradiator en_US
dc.title Novel inorganic scintillating detectors and their applications in small animal irradiators: measurements and Monte Carlo simulations en_US
dc.type info:eu-repo/semantics/conferenceObject en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1117/12.2551148
dc.contributor.sponsor IRC en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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