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Reducing sample consumption for serial crystallography using acoustic drop ejection

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dc.contributor.author Davy, Bradley
dc.contributor.author Axford, Danny
dc.contributor.author Beale, John H.
dc.contributor.author Butryn, Agata
dc.contributor.author Docker, Peter
dc.contributor.author Ebrahim, Ali
dc.contributor.author Leen, Gabriel
dc.contributor.author Orville, Allen M.
dc.contributor.author Owen, Robin L.
dc.contributor.author Aller, Pierre
dc.date.accessioned 2019-09-11T08:12:24Z
dc.date.available 2019-09-11T08:12:24Z
dc.date.issued 2019
dc.identifier.uri http://hdl.handle.net/10344/8040
dc.description peer-reviewed en_US
dc.description.abstract Efficient sample delivery is an essential aspect of serial crystallography at both synchrotrons and X-ray free-electron lasers. Rastering fixed target chips through the X-ray beam is an efficient method for serial delivery from the perspectives of both sample consumption and beam time usage. Here, an approach for loading fixed targets using acoustic drop ejection is presented that does not compromise crystal quality, can reduce sample consumption by more than an order of magnitude and allows serial diffraction to be collected from a larger proportion of the crystals in the slurry en_US
dc.language.iso eng en_US
dc.publisher International Union of Crystallography en_US
dc.relation.ispartofseries Journal of Synchrotron Radiation;26
dc.subject serial crystallography en_US
dc.subject sample delivery en_US
dc.subject fixed targets en_US
dc.title Reducing sample consumption for serial crystallography using acoustic drop ejection en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1107/S1600577519009329
dc.contributor.sponsor UK Government en_US
dc.contributor.sponsor Wellcome Trust en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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