Browsing Centres Education & Health Sciences by Author "Graduate Entry Medical School, University of Limerick"

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Role of circulating ﬁbrocytes in the diagnosis of acute appendicitis

Zarog, M. A.; O'Leary, D.P.; Kiernan, Miranda G.; Bolger, J.; Tibbitts, Paul; Coffey, S. N.; Lowery, A.; Byrnes, G. J.; Peirce, Colin; Dunne, Colum P.; Coffey, Calvin J. (Wiley, 2020)

Background: Improved diagnostic biomarkers are required for acute appendicitis. The circulating fibrocyte percentage (CFP) is increased in inflammatory states, but has not been studied in acute appendicitis. This study ...
Systemic molecular mediators of inflammation differentiate Between crohn’s disease and ulcerative colitis, implicating threshold levels of IL-10 and relative ratios of pro-inflammatory cytokines in therapy

Kiernan, Miranda G.; Coffey, Calvin J.; Sahebally, Shaheel M.; Tibbitts, Paul; Lyons, Emma May; O’Leary, Eimear; Owolabi, Funke; Dunne, Colum P. (Oxford University Press, 2019)

Background and Aims: Faecal diversion is associated with improvements in Crohn’s disease but not ulcerative colitis, indicating that differing mechanisms mediate the diseases. This study aimed to investigate levels of ...

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