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Browsing Centres Education & Health Sciences by Author "Coffey, Calvin J."

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Browsing Centres Education & Health Sciences by Author "Coffey, Calvin J."

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  • Coffey, Calvin J.; Kiernan, Miranda G. (Elsevier, 2017)
    Crohn's disease is hallmarked by mesenteric abnormalities including thickening, shortening and extension ofmesenteric fat over the intestinal surface (“fat wrapping” or “creeping fat”) (Coffey et al., 2016; Peyrin-Biroulet ...
  • Dowling, Lisa; Jakeman, Philip M.; Norton, Catherine; Skelly, Maeve; Yousuf, Hamid; Kiernan, Miranda G.; Toomey, Margaret; Bowers, Sheila; Dunne, Suzanne S.; Coffey, Calvin J.; Dunne, Colum P. (SpringerNature, 2021)
    Crohn’s disease (CD) is a debilitating inflammatory bowel condition of unknown aetiology that is growing in prevalence globally. Large-scale studies have determined associations between female obesity or low body mass ...
  • Dunne, Suzanne S.; Coffey, Calvin J.; Konje, Swiri; Gasior, Sara; Clancy, Conor C.; Gulati, Gautam; Meagher, David; Dunne, Colum P. (Elsevier, 2021)
    Background: Delirium is a common neuropsychiatric disorder associated with prolonged hospital stays, and increased morbidity and mortality. Diagnosis is frequently missed due to varying disease presentation and lack of ...
  • O'Connor, Ciara; O'Connell, Nuala H.; Power, Lorraine; Merrigan, Anne; Tormey, Shona M.; Coffey, Calvin J.; Linnane, Barry; Dunne, Colum P. (Society for General Microbiology, 2014)
    Introduction: Neonatal mastitis is an inflammatory condition of the breast frequently associated with Staphylococcus aureus. While Panton–Valentine leucocidin (PVL), a B-pore-forming cytotoxin, is commonly associated ...
  • O'Connell, Nuala H.; O'Connor, Ciara; O'Mahony, Jim; Lobo, Ronstan; Hayes, Maria; Masterson, Eric; Larvin, Michael; Coffey, Calvin J.; Dunne, Colum P. (Landes Bioscience, 2014)
    Prosthetic joints and other orthopaedic implants have improved quality of life for patients world-wide and the use of such devices is increasing. However, while infection rates subsequent to associated surgery are ...
  • Chang, K.H.; Johnson, J.H.; Waldron, David; Condon, E.T.; El-Bassiouni, M.; Coffey, Calvin J. (Elsevier, 2015)
    Introduction: The anal verge is key in determining measurement-based suitability for neoadjuvant radiotherapy in rectal cancer. The dentate line is a distinct anatomic landmark and may permit more accurate measurement ...
  • O'Leary, Peter D.; Coffey, Calvin J. (Taylor and Francis, 2017)
    Categorisation of structures into tissues, organs and systems is arbitrary but has considerable utility as it provides a structural hierarchy within which one can more easily investigate and better understand human biology ...
  • Lavelle, Aonghus; Lennon, Grainne; Docherty, Neil G.; Balfe, Áine; Mulcahy, Hugh E; Doherty, Glen; O'Donoghue, Diarmuid; Hyland, John M; Shanahan, Fergus; Sheahan, Kieran; Coffey, Calvin J.; Winter, Desmond C.; O'Connell, Ronan P. (Public Library of Science, 2013)
    Objective: The aims of this study were to develop techniques for spatial microbial assessment in humans and to establish colonic luminal and mucosal spatial ecology, encompassing longitudinal and cross-sectional axes. Design: ...
  • Byrnes, Kevin G.; Walsh, Dara; Walsh, Leon G.; Coffey, Domhnall M.; Ullah, Muhammad Fahad; Mirapeix, Rosa; Hikspoors, Jill; Lamers, Wouter; Wu, Yi; Zhang, Xiao-Qin; Zhang, Shao-Xiang; Brama, Pieter; Dunne, Colum P.; O'Brien, Ian S.; Peirce, Colin; Shelly, Martin J.; Scanlon, Tim G.; Luther, Mary E.; Brady, Hugh D.; Dockery, Peter; McDermott, Kieran W.; Coffey, Calvin J. (Nature, 2021)
    The position of abdominal organs, and mechanisms by which these are centrally connected, are currently described in peritoneal terms. As part of the peritoneal model of abdominal anatomy, there are multiple mesenteries. ...
  • Kumar, Ashutosh; Faiq, Muneeb A.; Krishna, Hare; Kishan, Vijay; Raj, Gladwin V.; Coffey, Calvin J.; Jacob, Tony George (Frontiers Media, 2020)
    Introduction: The conventional model of abdominal anatomy described multiple mesenteries. Dissection techniques were based on this. Recent studies demonstrate the mesentery is continuous from duodenojejunal flexure to ...
  • Hayes, Christopher J.; Dowling, Catríona M.; Dwane, Susan; McCumiskey, Mary E.; Tormey, Shona M.; Merrigan, Anne; Coffey, Calvin J.; Kiely, Patrick A.; Dalton, Tara (AIP Publishing, 2016)
    In cancer, biomarkers have many potential applications including generation of a differential diagnosis, prediction of response to treatment, and monitoring disease progression. Many molecular biomarkers have been put ...
  • Kiernan, Miranda G.; Sahebally, Shaheel M.; Jarrar, Awad; Burke, J.P.; Hogan, J.; Kiely, Patrick A.; Shen, Bo; Moloney, M; Skelly, M.; Leddin, Des; Hedayat, H.; Faul, P.N.; Healy, Vourneen; O'Connell, Ronan P.; Martin, S.; Shanahan, Fergus; Dunne, Colum P.; Coffey, Calvin J. (Springer, 2016)
    no abstract available
  • Kiernan, Miranda G.; Coffey, Calvin J.; McDermott, Kieran W.; Cotter, Paul D.; Cabrera-Rubiod, Raul; Kiely, Patrick A.; Dunne, Colum P. (Oxford University Press, 2019)
    Background and Aims: Mesenteric lymph nodes are sites in which translocated bacteria incite and progress immunological responses. For this reason, understanding the microbiome of mesenteric lymph nodes in inflammatory ...
  • Powell, James; Finnegan, Cathriona; O'Gorman, A.; Barrett S.; Hopkins, K.L.; Pichon, B.; Hill, R.; Power, Lorraine; Woodford, Neil; Coffey, Calvin J.; Kearns, A.; O'Connell, Nuala H.; Dunne, Colum P.; O'Connor, Ciara (Elsevier, 2015)
    Aim: To report the first Irish outbreak of cfr-mediated linezolid-resistant Staphylococcus epidermidis. Methods: Linezolid-resistant S. epidermidis isolated at University Hospital Limerick from four blood cultures, one ...
  • Hogan, John; Judge, Conor; O'Callaghan, Michael; Aziz, Amir; O'Connor, Cormac; Burke, John; Dunne, Colum P.; Walsh, Stewart R.; Kalady, Matthew; Coffey, Calvin J. (Lippincott Williams & Wilkins, 2014)
    Objective: This study aims to harness the potential of public gene expression repositories, to develop gene expression profiles that could accurately determine nodal status in colorectal cancer. Background: Currently, ...
  • O'Connor, Ciara; Cormican, Martin; Wee Boo, Teck; McGrath, Elaine; Slevin, Barbara L.; O'Gorman, Alan; Commane, Marion; Mahony, Stephane; O'Donovan, Eimear; Powell, James; Monahan, Regina; Finnegan, Cathriona; Kiernan, Miranda G.; Coffey, Calvin J.; Power, Lorraine; O'Connell, Nuala H.; Dunne, Colum P. (Elsevier, 2016)
    Background Carbapenemase-producing Enterobacteriaceae (CPE) can cause healthcare–associated infections with high mortality rates. New Delhi metallo-beta-lactamase-1 (NDM-1) is amongst the most recently discovered ...
  • Balfe, Áine; Lennon, Grainne; Lavelle, Aonghus; Docherty, Neil G.; Coffey, Calvin J.; Sheahan, Kieran; Winter, Desmond C.; O'Connell, Ronan P. (Dove Medical Press, 2018)
    Aim: The epithelial layer within the colon represents a physical barrier between the luminal contents and its underlying mucosa. It plays a pivotal role in mucosal homeostasis, and both tolerance and anti-pathogenic immune ...
  • Solon, Gemma; Coffey, Calvin J.; McNamara, Deborah (Irish Medical Organisation, 2013)
    Increasing emergency admissions place significant demands on limited hospital resources. We assessed national practices and resources for initiatives to reduce length of stay (LOS) and thereby improve efficiency of ...
  • Sahebally, Shaheel M. (Univerisity of Limerick, 2017)
    Background Mesenteric manifestations are of pathobiologic relevance in Crohn’s disease. Clarification of mesenteric morphology provides an opportunity to re-appraise their pathogenic significance. Therefore, we examined ...
  • Kiernan, Miranda G.; Sahebally, Shaheel M.; Kiely, Patrick A.; Waldron, David; Moloney, M.; Skelly, M.; Faul, P.N.; O'Leary, D.P.; Lowery, Aoife J.; Walsh, Leon G.; Dunne, Colum P.; Coffey, Calvin J. (Oxford University Press, 2017)
    The mesentery in Crohn’s disease frequently displays disease manifestations, such as mesenteric thickening and fat wrapping. Fibrocytes are a precursor cell type that can differentiate into fibroblasts or adipocytes [1]. ...

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