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Pulmonary aspiration in preschool children with cystic fibrosis

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dc.contributor.author Clarke, Donna
dc.contributor.author Gorman, I.
dc.contributor.author Ringholz, F.
dc.contributor.author McDermott, M.
dc.contributor.author Cox, D.W.
dc.contributor.author Greally, Paul
dc.contributor.author Linnane, Barry
dc.contributor.author McNally, Paul
dc.date.accessioned 2019-01-03T16:58:23Z
dc.date.available 2019-01-03T16:58:23Z
dc.date.issued 2018
dc.identifier.uri http://hdl.handle.net/10344/7445
dc.description peer-reviewed en_US
dc.description.abstract Pulmonary aspiration of gastric refluxate (PAGR) has been demonstrated in association with pulmonary inflammation in school aged children with Cystic Fibrosis (CF). We sought to determine if similar findings were present in preschool children. Pepsin was measured in Broncho-alveolar lavage (BAL) fluid collected from clinically stable preschool children with CF and controls. Elevated pepsin levels were found in a subgroup of children with CF, but this was not found to be associated with pulmonary infection, pulmonary inflammation or respiratory or gastrointestinal symptoms. en_US
dc.language.iso eng en_US
dc.publisher BMC en_US
dc.relation.ispartofseries Respiratory Research;19:255
dc.relation.uri https://doi.org/10.1186/s12931-018-0954-1
dc.subject pulmonary aspiration en_US
dc.title Pulmonary aspiration in preschool children with cystic fibrosis en_US
dc.type info:eu-repo/semantics/contributionToPeriodical en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1186/s12931-018-0954-1
dc.contributor.sponsor National Children’s Research Centre en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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