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Browsing MACSI - Mathematics Application Consortium for Science & Industry by Title

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  • Systematic development of a high dosage formulation to enable direct compression of a poorly flowing API: a case study 
    Schaller, Barbara E.; Moroney, Kevin M.; Castro-Dominguez, Bernardo; Cronin, Patrick; Belen-Girona, Jorge; Ruane, Patrick; Croker, Denise M.; Walker, Gavin M. (Elsevier, 2019)
    In this work, the transfer of oral solid dosage forms, currently manufactured via wet granulation, to a continuous direct compression process was considered. Two main challenges were addressed: (1) a poorly flowing API ...
  • Temporal profiles of avalanches on networks 
    Gleeson, James P.; Durrett, Rick (Nature Publishing Group, 2017)
    An avalanche or cascade occurs when one event causes one or more subsequent events, which in turn may cause further events in a chain reaction. Avalanching dynamics are studied in many disciplines, with a recent focus on ...
  • Transport in randomly-fluctuating spatially-periodic potentials 
    Gleeson, James P. (2009)
    The motion of overdamped particles in a one-dimensional spatially-periodic potential is considered. The potential is also randomly-fluctuating in time, due to multiplicative colored noise terms, and has a deterministic ...
  • Understanding the challenges and uncertainties of seroprevalence studies for SARS-CoV-2 
    McConnell, David; Hickey, Conor; Bargary, Norma; Trela-Larsen, Lea; Walsh, Cathal Dominic; Barry, Michael; Adams, Roisin (MDPI, 2021)
    SARS-CoV-2 continues to widely circulate in populations globally. Under detection is acknowledged and is problematic when attempting to capture the true prevalence. Seroprevalence studies, where blood samples from a ...
  • The unreasonable effectiveness of tree-based theory for networks with clustering 
    Melnik, Sergey; Hackett, Adam W.; Porter, Mason A; Mucha, Peter J; Gleeson, James P. (American Physical Society, 2011)
    We demonstrate that a tree-based theory for various dynamical processes operating on static, undirected networks yields extremely accurate results for several networks with high levels of clustering. We find that such a ...
  • Waves in Guinness 
    Robinson, Marguerite; Fowler, Andrew C.; Alexander, A.J.; O'Brien, Stephen B.G. (American Institute of Physics, 2008)
    We describe a simple model of a bubbly two-phase flow which is able to explain why waves propagate downward when a pint of Guinness is poured, and also how the waves are generated. Our theory involves a physically based ...
  • Weak percolation on multiplex networks 
    Baxter, Gareth J.; Dorogovtsev, Sergey N.; Mendes, José F.F.; Cellai, Davide (Americann Physical Society, 2014)
    Bootstrap percolation is a simple but nontrivial model. It has applications in many areas of science and has been explored on random networks for several decades. In single-layer (simplex) networks, it has been recently ...

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