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An analytical framework for delirium research in palliative care settings: integrated epidemiologic, clinician-researcher, and knowledge user perspectives

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dc.contributor.author Lawlor, Peter G.
dc.contributor.author Davis, Daniel H.J.
dc.contributor.author Ansari, Mohammed T.
dc.contributor.author Hosie, Annmarie
dc.contributor.author Kanji, Salmaan
dc.contributor.author Momoli, Franco
dc.contributor.author Bush, Shirley H.
dc.contributor.author Watanabe, Sharon
dc.contributor.author Currow, David C.
dc.contributor.author Gagnon, Bruno
dc.contributor.author Agar, Meera
dc.contributor.author Bruera, Eduardo
dc.contributor.author Meagher, David
dc.contributor.author de Rooij, Sophia E.J.A.
dc.contributor.author Adamis, Dimitrios
dc.contributor.author Caraceni, Augusto
dc.contributor.author Marchington, Katie
dc.contributor.author Stewart, David J.
dc.date.accessioned 2018-10-25T11:30:13Z
dc.date.available 2018-10-25T11:30:13Z
dc.date.issued 2014
dc.identifier.uri http://hdl.handle.net/10344/7256
dc.description peer-reviewed en_US
dc.description.abstract Context. Delirium often presents difficult management challenges in the context of goals of care in palliative care settings. Objectives. The aim was to formulate an analytical framework for further research on delirium in palliative care settings, prioritize the associated research questions, discuss the inherent methodological challenges associated with relevant studies, and outline the next steps in a program of delirium research.Methods. We combined multidisciplinary input from delirium researchers and knowledge users at an international delirium study planning meeting, relevant literature searches, focused input of epidemiologic expertise, and a meeting participant and coauthor survey to formulate a conceptual research framework and prioritize research questions.Results. Our proposed framework incorporates three main groups of research questions: the first was predominantly epidemiologic, such as delirium occurrence rates, risk factor evaluation, screening, and diagnosis; the second covers pragmatic management questions; and the third relates to the development of predictive models for delirium outcomes. Based on aggregated survey responses to each research question or domain, the combined modal ratings of "very'' or "extremely'' important confirmed their priority.Conclusion. Using an analytical framework to represent the full clinical care pathway of delirium in palliative care settings, we identified multiple knowledge gaps in relation to the occurrence rates, assessment, management, and outcome prediction of delirium in this population. The knowledge synthesis generated from adequately powered, multicenter studies to answer the framework's research questions will inform decision making and policy development regarding delirium detection and management and thus help to achieve better outcomes for patients in palliative care settings. (C) 2014 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved. en_US
dc.language.iso eng en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Journal of Pain and Symtom Management;48 (2), pp. 159-175
dc.relation.uri https://doi.org/10.1016/j.jpainsymman.2013.12.245
dc.subject Delirium en_US
dc.subject palliative care en_US
dc.subject risk factors en_US
dc.subject decision making en_US
dc.subject hospice en_US
dc.subject research framework en_US
dc.subject assessment en_US
dc.subject treatment en_US
dc.subject predictive model en_US
dc.title An analytical framework for delirium research in palliative care settings: integrated epidemiologic, clinician-researcher, and knowledge user perspectives en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.date.updated 2018-10-25T11:19:40Z
dc.description.version PUBLISHED
dc.identifier.doi 10.1016/j.jpainsymman.2013.12.245
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1573212
dc.internal.copyrightchecked Yes
dc.identifier.journaltitle Journal Of Pain And Symptom Management
dc.description.status peer-reviewed


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