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Association of height with elevated mortality risk in ESRD: variation by race and gender

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Show simple item record Elsayed, Mohamed E. Ferguson, John P. Stack, Austin G. 2018-10-19T11:56:30Z 2018-10-19T11:56:30Z 2016
dc.description peer-reviewed en_US
dc.description.abstract The association of adult height withmortality has been extensively investigated in the general population, but little is known about this relationship among dialysis patients. We explored the relationship between height and mortality in a retrospective cohort study of 1,171,842 adults who began dialysis in the United States from 1995 to 2008 and were followed until December 31, 2010. We evaluated height-mortality associations in sex-specific quintiles of increasing height (Q1–Q5) using multivariable Cox regression models adjusted for demographics, comorbid conditions, lifestyle and disability indicators, socioeconomic status, and body weight. For men, compared with the referent quintile (Q1 ,167 cm), successive height quintiles had significantly increased hazard ratios (HRs [95%confidence interval]) for mortality: 1.04 (1.02–1.06), 1.08 (1.06–1.10), 1.12 (1.11–1.14), and 1.18 (1.16–1.20) for Q2–Q5, respectively. For women (referentQ1,155 cm),HRs formortality were 1.00 (0.99–1.02), 1.05 (1.03–1.06), 1.05 (1.03–1.07), and 1.08 (1.06–1.10) for Q2–Q5, respectively. However, stratification by race showed the pattern of association differed significantly by race (P,0.001 for interaction). For blackmen, unlike other race groups, height only associated with mortality in Q5, with an HR of 1.06 (1.02–1.09). For black women, HRs for mortality were 0.94 (0.91–0.97), 0.98 (0.95–1.02), 0.96 (0.93–0.99), and 0.99 (0.96–1.02) for Q2–Q5, respectively. These results indicate tallness is associated with higher mortality risks for adults starting dialysis, but this association did not extend to black patients. en_US
dc.language.iso eng en_US
dc.publisher Dove Medical Press en_US
dc.relation.ispartofseries Clinical Epidemiology;27, pp. 590-593
dc.rights First published by Dove Medical Press © 2016 en_US
dc.subject adult height en_US
dc.subject mortality en_US
dc.subject dialysis patients en_US
dc.title Association of height with elevated mortality risk in ESRD: variation by race and gender en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1681/ASN.2014080821
dc.contributor.sponsor HRB en_US
dc.relation.projectid HRA-2013-PHR-685 en_US
dc.relation.projectid HRA-2013-PHR-437 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US

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