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Particulate matter and hospital admissions for stroke in Beijing, China: modification effects by ambient temperature

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dc.contributor.author Huang, Fangfang
dc.contributor.author Luo, Yanxia
dc.contributor.author Guo, Yuming
dc.contributor.author Tao, Lixin
dc.contributor.author Xu, Qin
dc.contributor.author Wang, Chao
dc.contributor.author Wang, Anxin
dc.contributor.author Li, Xia
dc.contributor.author Guo, Jin
dc.contributor.author Yan, Aoshuang
dc.contributor.author Guo, Xiuhua
dc.date.accessioned 2018-01-08T12:32:03Z
dc.date.available 2018-01-08T12:32:03Z
dc.date.issued 2016
dc.identifier.uri http://hdl.handle.net/10344/6411
dc.description peer-reviewed en_US
dc.description.abstract Background-—The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013–2014. Methods and Results-—A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959–2.190), 1.470 (95% CI 1.391–1.554), and 1.590 (95% CI 1.493–1.694) per IQR increase in the same-day PM2.5 (82.0 lg/ m3), PM2.5–10 (36.6 lg/m3), and PM10 (93.5 lg/m3), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658–2.273), 1.590 (95% CI 1.366–1.851), and 1.527 (95% CI 1.278–1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C). Conclusions-—This study suggests that the associations of PM2.5, PM2.5–10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5–10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C). en_US
dc.language.iso eng en_US
dc.publisher Wiley Open Access en_US
dc.relation.ispartofseries Journal of the American Heart Association;5:e003437
dc.relation.uri http://dx.doi.org/10.1161/JAHA.116.003437
dc.subject air pollution en_US
dc.subject hospital admission en_US
dc.subject particulate matter en_US
dc.subject stroke en_US
dc.title Particulate matter and hospital admissions for stroke in Beijing, China: modification effects by ambient temperature en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1161/JAHA.116.003437
dc.contributor.sponsor Beijing Municipal Science & Technology Commission en_US
dc.contributor.sponsor Key Projects in the National Science & Technology Pillar Program in the Twelfth Five-year Plan Period of China en_US
dc.contributor.sponsor Program of Natural Science Fund of China en_US
dc.contributor.sponsor Career Development Fellowship of Australian National Health and Medical Research Council en_US
dc.relation.projectid D141100000114003 en_US
dc.relation.projectid 2011BAI08B01 en_US
dc.relation.projectid 81530087 en_US
dc.relation.projectid APP1107107 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US


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