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Online neurocognitive remediation therapy to improve cognition in community-living individuals with a history of depression: A pilot study

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dc.contributor.author Semkovska, Maria
dc.contributor.author Ahern, Elayne
dc.date.accessioned 2017-11-23T09:27:08Z
dc.date.available 2017-11-23T09:27:08Z
dc.date.issued 2017
dc.identifier.uri http://hdl.handle.net/10344/6291
dc.description peer-reviewed en_US
dc.description.abstract Major depression is a highly prevalent psychopathology with high relapse rates. Following remission from a depressive episode, neurocognitive difficulties in attention, working memory and executive function often persist, preventing full clinical recovery. These neurocognitive deficits are often present since the first depressive episode and have been shown to predict relapse. The efficacy of computerised neurocognitive remediation therapy (NCRT) to improve attention, memory and executive function has been demonstrated in several clinical populations but randomised controlled trials (RCT) have not been conducted in depression. The present study aimed to conduct a pilot, randomised study, of computerised NCRT for individuals with past depression, currently in remission. Twenty two individuals remitted from depression were randomly assigned to receive 20 one-hour sessions over 5 week of ether computerised NCRT or a component-equivalent allocation (play online computer games). The NCRT group showed significantly larger improvements in performance relative to the Games group in the three targeted neurocognitive domains: divided attention, verbal working memory, and planning, but also in non-targeted domains of long-term verbal memory and switching abilities. No significant effect was observed in the NCRT-targeted domain visual working memory. These preliminary results suggest computerised NCRT efficacy to improve targeted neurocognitive processes during depression remission and support its potential value as preventative connected intervention tool. en_US
dc.language.iso eng en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Internet Interventions;9, pp. 7-14
dc.relation.uri http://dx.doi.org/10.1016/j.invent.2017.04.003
dc.subject computerised intervention en_US
dc.subject neurocognitive remediation therapy en_US
dc.subject major depression en_US
dc.subject remission en_US
dc.subject divided attention en_US
dc.subject working memory en_US
dc.subject executive function en_US
dc.subject pilot study en_US
dc.title Online neurocognitive remediation therapy to improve cognition in community-living individuals with a history of depression: A pilot study en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1016/j.invent.2017.04.003
dc.contributor.sponsor IRC en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 2870643


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