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P026 The role of fibrocytes in mesenteric Crohn's disease.
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P026 The role of fibrocytes in mesenteric Crohn's disease.
Kiernan, Miranda G.; Sahebally, Shaheel M.; Kiely, Patrick A.; Waldron, David; Moloney, M.; Skelly, M.; Faul, P.N.; O'Leary, D.P.; Lowery, Aoife J.; Walsh, L.G.; Dunne, Colum P.; Coffey, John C.
Date:
2017
Publication:
Journal of Crohn's and Colitis;11, supplement (1), S92-S93
Publication type:
Article
Abstract:
The mesentery in Crohn’s disease frequently displays disease manifestations, such as
mesenteric thickening and fat wrapping. Fibrocytes are a precursor cell type that can
differentiate into fibroblasts or adipocytes [1]. They have previously been identified in the
mesentery in inflammatory conditions such as mesenteric panniculitis [2]. This study aimed to
investigate the role of fibrocytes in Crohn’s mesenteric disease manifestations.
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Kiernan, Miranda G.; Sahebally, Shaheel M.; Waldron, David; Moloney, M.; Skelly, M.; HIdayat, H.; O'Leary, D.P.; Lowery, Aoife J.; Walsh, L.G.; Dunne, Colum P.; Coffey, John C. (Oxford University Press, 2017)Crohn’s disease (CD) displays mesenteric disease manifestations such as fat wrapping and mesenteric thickening. The frequency at which these occur in CD point to a pathobiological relevance. Fat wrapping in particular ...
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