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Browsing Doctoral theses (SE) by Author

Browsing Doctoral theses (SE) by Author "Walsh, Michael T."

Now showing items 1-15 of 15

Improving the diagnosis and treatment of atherosclerosis: targeting calcification as a basis for patient management

Cahalane, Rachel M. (University of Limerick, 2020)

The presence of atherosclerotic calcification serves as a surrogate marker for plaque burden and a prognostic marker of cardiovascular risk. Additionally, calcification plays a critical role in plaque stability and ...
An investigation into the effects of mechanical loading patterns from everyday activities on long term stability after cementless hip replacement surgery.

O'Reilly, David S. (University of Limerick, 2011)

The number of Total Hip Replacement (THR) surgeries carried out per year is increasing year on year as people live longer and partake in a more active lifestyle. Other factors such as obesity and weight problems are also ...
Modelling diffusion from drug eluting stents in compressed arterial tissue

Denny, William John (University of Limerick, 2013)

Coronary artery disease is atherosclerosis of the coronary arteries that results in blockages or narrowing of the arterial wall, is caused by the accumulation of lipid-laden atherosclerotic plaque. Drug eluting stents ...
On the characterisation of abdominal aortic tissues

O'Leary, Siobhan Ann (University of Limerick, 2014)

Abdominal aortic aneurysm (AAA) is the gradual and irreversible expansion of the distal region of the aorta. It can be defined as a balloon like dilation 1.5 times the diameter of the normal abdominal aorta. The prevalence ...
On the development of assessment techniques for improved prediction of arteriovenous graft performance in facilitating haemodialysis

Broderick, Stephen P. (University of Limerick, 2014)

Renal failure is a condition where the kidneys cannot provide sufficient filtration of waste product from the blood. A kidney transplant is the ideal treatment, but donor numbers fall short of demand. The alternative ...
On the mechanical and morphological characterisation of calcification in diseased vascular tissue

Barrett, Hilary E. (University of Limerick, 2017)

Vascular calcification, a complex component that forms in the walls of arteries as part of advanced cardiovascular disease (CVD), triggers severe arterial complications and negatively impacts the success of endovascular ...
Quantifying the hemodynamic characteristics of an arteriovenous fistula used for hemodialysis

Browne, Leonard D. (University of Limerick, 2015)

Chronic kidney disease refers to an irreversible, progressive reduction of the renal function of kidneys. When there is a significant loss of renal function a replacement therapy is sought. A kidney transplant is the optimal ...
A quantitative analysis of the environmental impact of hill farming in relation to vegetation, soil attributes and soil erosion: a land use perspective.

Walsh, Michael T. (University of Limerick, 2011)

The research was carried out in conjunction with the commercially run Teagasc Hill Sheep Farm, Leenaun, Co. Mayo and with Met Éireann. The aim was to enhance habitat status and to maximise biodiversity conservation in ...
Towards the development of a physiologically mimetic tissue engineered cardiovascular graft for the treatment of abdominal aortic aneurysms

Davis, Laura M. (University of Limerick, 2014)

With cardiovascular pathologies continuing to prevail, effective arterial replacements for the minimally invasive treatment of abdominal aortic aneurysms (AAAs) through endovascular aneurysm repair (EVAR) are still an ...
Towards the development of guidelines for the endovascular treatment of peripheral artery disease: a tissue characterisation approach

Cunnane, Eoghan M. (University of Limerick, 2015)

The femoral arteries are one of the most susceptible vascular locations for the development of atherosclerosis. The occurrence of this disease process in these vessels is the leading cause of lifestyle-limiting claudication ...
Towards the development of guidelines for the surgical treatment of carotid artery disease: a cranial perfusion approach

Lynch, Adrian Gerard (University of Limerick, 2013)

The development of carotid artery disease in the form of atherosclerotic plaque and the progressive narrowing of the carotid artery lumen is the leading cause of stroke, the third most prevalent cause of death in the ...
Towards the development of guidelines for the surgical treatment of carotid artery disease: a tissue characterisation approach

Mulvihill, John J.E. (University of Limerick, 2013)

Despite the proven efficacy of carotid endarterectomy (CEA), great interest has been generated in carotid angioplasty and stenting (CAS) as an alternative to CEA. The stretch caused by balloon angioplasty deployment ...
Towards the prediction of breast cancer cell behaviour in the lymphatics using in vitro and in silico methods

Morley, Sinéad T. (University of Limerick, 2017)

Breast cancer is the most common malignant cancer form in women and an estimated 318,000 new cases of breast cancer will be diagnosed in 2017. Metastasis accounts for 90% of cancer related deaths and the lymphatics ...
Towards the use of geometric parameters and blood-borne species concentration in the prediction of cerebral aneurysm growth and rupture

Costeloe, Jennifer Ann (University of Limerick, 2015)

The rupture of a cerebral aneurysm can have devastating effects, with high rates of morbidity and mortality associated with the event. Approximately 12% of patients who suffer a subarachnoid haemorrhage due to the rupture ...
The variation of median nerve functionality with wrist postures typical of computer use and a novel ultrasound technique for the diagnosis of carpal tunnel syndrome

Donoghue, Maurice F (University of Limerick, 2011)

Carpal tunnel syndrome (CTS) is an affliction that affects numerous people in an occupational and recreational environment. One area commonly linked to the development of this condition is computer use. This is due to ...

Browsing Doctoral theses (SE) by Author "Walsh, Michael T."

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