• Investigation of the relationship between training load, monitoring markers of recovery, injury, and illness in elite team sports 

  Tiernan, Caoimhe (University of Limerick, 2020)

  Introduction: In elite athletes, the margins between success and failure are very small, and so to optimise performance, reduce the risk of injury and illness, coaches need to prescribe the correct balance between ...
• Improving the diagnosis and treatment of atherosclerosis: targeting calcification as a basis for patient management 

  Cahalane, Rachel M. (University of Limerick, 2020)

  The presence of atherosclerotic calcification serves as a surrogate marker for plaque burden and a prognostic marker of cardiovascular risk. Additionally, calcification plays a critical role in plaque stability and ...
• Spray drying of pharmaceuticals and biopharmaceuticals: experimental optimization of process and formulation 

  Ziaee, Ahmad (University of Limerick, 2019)

  Oral consumption is the most commonly used method of small molecule drug delivery due to its simple administration, flexible formulation design, cost-effectiveness and established production technology. The typical ...
• Crystal growth kinetics of salicylamide and two polymorphs of piracetam 

  Lynch, Aisling (University of Limerick, 2019)

  The crystal growth process and associated kinetics of two active pharmaceutical ingredients (API) has been investigated using three crystal growth methods. The impact of organic solvent, supersaturation, temperature, ...
• Circumferential compression of the lower limb and implications for soft exoskeleton design 

  Kermavnar, Tjaša (University of Limerick, 2019)

  A variety of pathologies impair human gait by reducing the ability to control the lower limbs, which causes the need for gait-assistive devices. The increase in interest and the advances in wearable-robot technologies ...
• Crowd-Induced vibrations in sports stadia analysis of Thomond Park Stadium under concert events 

  Zhang, Hua (University of Limerick, 2019)

  The potential of dynamic structural response to cause serviceability or even ultimate failure in building structures has long been known. The availability of stronger structural materials and more precise analysis tools ...
• Deciphering the molecular signatures of neurodegeneration by predictive computational modelling 

  Bhattacharya, Shayon (University of Limerick, 2019)

  Amyloids are fibrillary aggregates identified in over 40 human diseases, including neurodegenerative diseases encompassing Alzheimer’s (AD), Parkinson’s (PD), Huntington’s and Prion diseases. Amyloids form by spontaneous ...
• The influence of a growing microbial biomat on water retention and pollutant attenuation in soil treatment units receiving domestic effluent 

  Kanppe, Jan (University of Limerick, 2019)

  Soil treatment units (STUs) are an integral component of most domestic on-site wastewater treatment systems. Understanding their long-term environmental impacts and performance will help to improve design guidelines and ...
• Detection of anti-social behaviour in online communication in Arabic 

  Alakrot, Azalden (University of Limerick, 2019)

  Anti-social behaviour on social media cannot be easily ignored as it affects a large and growing percentage of the world’s population. It often has a nega tive effect on people’s lives; incidents of online abuse that may ...
• An investigation into the effect of impurities on the crystallization of curcumin 

  Heffernan, Claire (University of Limerick, 2019)

  This thesis investigates the influence of two structurally related impurities, Demethoxycurcumin and Bisdemethoxycurcumin, on the crystallization of Curcumin. Firstly, a purification technique was designed and used to ...
• Profile development in population studies: clustering and latent class methodologies 

  O'Neill, Aoife (University of Limerick, 2019)

  Identifying subgroups within a population can provide important insights to decision makers. When concerned with health data, identifying profiles of individuals who share similar characteristics may inform targeted ...
• A mechanistic model for particle breakage within agitated crystallization systems 

  Tyrrell, Rory (University of Limerick, 2019)

  Throughout the field of particulate processing the application of modelling techniques to predict, optimize, or otherwise enhance processes is widespread. Perhaps the most common technique when it comes to modelling ...
• Towards the prediction of breast cancer cell behaviour in the lymphatics using in vitro and in silico methods 

  Morley, Sinéad T. (University of Limerick, 2017)

  Breast cancer is the most common malignant cancer form in women and an estimated 318,000 new cases of breast cancer will be diagnosed in 2017. Metastasis accounts for 90% of cancer related deaths and the lymphatics ...
• Investigations of electric field assembly of colloidal rod shaped nanocrystals and their device applications 

  Liu, Pai (University of Limerick, 2017)

  This thesis focuses on the assembly of anisotropic nanocrystals using an electric field assisted assembly method. The studies involve the precise control of electrophoretic deposition (EPD) in a non-polar solvent causing ...
• Empirical and process-based modelling of soil respiration in afforested peatlands 

  Jovani-Sancho, Antonio Jonay (University of Limerick, 2017)

  Worldwide peatlands cover about 3% of the Earth’s land surface and it is estimated that they store about 610 Pg C. Some 50 million ha of peatlands have been drained and converted to another land-use. After drainage the ...
• Optimising the use of fresh semen: insights for use with young genomically-selected bulls 

  Holden, Shauna A. (University of Limerick, 2017)

  With the advent of genomic selection, bulls are being used in the artificial insemination industry during early puberty. These young bulls produce ejaculates of low volume and low spermatozoa concentration that are ...
• On the mechanical and morphological characterisation of calcification in diseased vascular tissue 

  Barrett, Hilary E. (University of Limerick, 2017)

  Vascular calcification, a complex component that forms in the walls of arteries as part of advanced cardiovascular disease (CVD), triggers severe arterial complications and negatively impacts the success of endovascular ...
• Mathematical approaches for improved thermal performance in buildings, simulations, data mining and neural networks 

  Hillary, Jason (University of Limeick, 2017)

  Thermal operations in residential and commercial buildings account for a significant proportion of the primary energy consumption within both Europe and the United States. Owing to the myriad of factors influencing ...
• Nanoporous gold electrodes for application in trace metal sensors, biosensors and biofuel cells 

  Siepenkötter, Till (University of Limerick, 2017)

  Nanoporous Gold (NPG) is a material of emerging interest for immobilization of biomolecules and especially enzymes. NPG materials provide a high surface area onto which biomolecules can either be directly physisorbed, ...
• Interpenetrated hybrid ultramicroporous materials: insight into structure-property relationships 

  O'Nolan, Daniel (University of Limerick, 2018)

  Crystal Engineering is the field of chemistry that studies the design, properties, and application of crystalline materials. An aspect of crystal engineering is the design of coordination networks using linker ligands ...

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