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Psychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study

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dc.contributor.author Boland, Fiona
dc.contributor.author Galvin, Rose
dc.contributor.author Reulbach, Udo
dc.contributor.author Motterlini, Nicola
dc.contributor.author Kelly, Dervla
dc.contributor.author Bennett, Kathleen
dc.contributor.author Fahey, Tom
dc.date.accessioned 2015-11-18T16:48:36Z
dc.date.available 2015-11-18T16:48:36Z
dc.date.issued 2015
dc.identifier.uri http://hdl.handle.net/10344/4742
dc.description peer-reviewed en_US
dc.description.abstract Background: Psychotropic paediatric prescribing trends are increasing internationally. The aim of this study is to examine the prevalence and secular trends in psychotropic prescribing in Irish children and adolescents between 2002 and 2011. Methods: Data was obtained from the Irish General Medical Services (GMS) scheme pharmacy claims database from the Health Service Executive Primary Care Reimbursement Services (HSE-PCRS). Prescribing rates per 1000 eligible population and associated 95 % confidence intervals (CIs) were calculated across years (2002–2011), age groups (0–4, 5–11, 12–15 years) and gender. Rates of concomitant prescriptions for psycholeptics and antidepressants were also examined. The total expenditure costs were calculated and expressed as a percentage of the cost of all prescriptions for this age group (≤15 years). Results: In 2002, 3.77/1000 GMS population (95 % CI: 3.53–4.01) received at least one psychostimulant prescription and this rate increased to 8.63/1000 GMS population (95 % CI: 8.34–8.92) in 2011. Methylphenidate was the most frequently prescribed psychostimulant. For both males and females the prevalence of medication use was highest among the 12–15 year old group. On average, a psycholeptic medication was prescribed to 8 % of all psychostimulant users and an antidepressant was concomitantly prescribed on average to 2 %. Total expenditure rose from €89,254 in 2002 to €1,532,016 in 2011. Conclusions: The rate and cost of psychostimulant prescribing among GMS children and adolescents in Ireland increased significantly between 2002 and 2011. Further research is necessary to assess the safety, efficacy and economic impact of concomitant psychotropic prescribing in this population. en_US
dc.language.iso eng en_US
dc.publisher BioMed Central en_US
dc.relation.ispartofseries BMC Pediatrics;15: 118
dc.subject children en_US
dc.subject pharmacoepidemiology en_US
dc.subject ADHD en_US
dc.subject psychostimulant treatment en_US
dc.title Psychostimulant prescribing trends in a paediatric population in Ireland: a national cohort study en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1186/s12887-015-0435-3
dc.contributor.sponsor HRB en_US
dc.relation.projectid HRC/2007/1 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1597808


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