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Label free detection of specific protein binding using a microwave sensor

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dc.contributor.author Alvarez, Marcela Salazar
dc.contributor.author Korostynska, Olga
dc.contributor.author Mason, Alex
dc.contributor.author Al Ahamma'a, Ahmed
dc.contributor.author Cooney, Jakki C.
dc.contributor.author Magner, Edmond
dc.contributor.author Tofail, Syed A.M.
dc.date.accessioned 2015-10-30T13:00:16Z
dc.date.available 2015-10-30T13:00:16Z
dc.date.issued 2014
dc.identifier.uri http://hdl.handle.net/10344/4697
dc.description peer-reviewed en_US
dc.description.abstract The specific binding of streptavidin to biotinylated protein A was demonstrated using a microwave detection system. In control experiments, the degree of non-specific binding was negligible. The method of detection was used to monitor the adsorption of two other proteins, cytochrome c and glucose oxidase, on to the IDE microwave sensor surface. The response of the sensor was also examined on different substrate materials, with detection of protein binding observed obtained on both smooth, conductive (gold) and on rough, insulating (hydroxyapatite) surfaces. en_US
dc.language.iso eng en_US
dc.publisher Royal Society of Chemistry en_US
dc.relation info:eu-repo/grantAgreement/EC/FP7/275201 en_US
dc.relation.ispartofseries Analyst;139, pp. 5335-5338
dc.relation.uri http://dx.doi.org/10.1039/c4an00909f
dc.subject microwave detection system en_US
dc.subject protein binding en_US
dc.title Label free detection of specific protein binding using a microwave sensor en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1039/c4an00909f
dc.contributor.sponsor ERC en_US
dc.relation.projectid 275201 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1573262


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