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Health Research Institute (HRI)

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Health Research Institute (HRI)

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The Health Research Institute (HRI) is a cross faculty institute that brings together researchers in UL and its partner institutions with a focus on convergent and translational health research. The mission of the HRI is to conduct outstanding transformative research in order to improve the health and well-being of individuals, patients, communities and populations. The HRI research activity is structured around the following thematic areas:

  • Technology Enhanced Health Outcomes
  • Lifestyle and Health
  • Health Service Delivery

The activities of the HRI are supported by expertise in biostatistics, health informatics and health economics, and facilitated by the Clinical Research Support Unit (CRSU). The UL/UL Hospitals Clinical Research Unit (CRU) is the first agreed CRSU partnership and is located at University Hospital Limerick (UHL). Our goal is to provide a rich collaborative environment that fosters discovery and innovation in health science that will lead to better health, improved care and a healthier society.

For more information see the HRI website.

Recent Submissions

  • Stack, Austin G.; Dronamraju, Nalina; Parkinson, Joanna; Johansson, Susanne; Johnsson, Eva; Erlandsson, Fredrik; Terkeltaub, Robert (Elsevier, 2020)
    Rationale & Objective: Hyperuricemia has been implicated in the development and progression of chronic kidney disease. Verinurad is a novel, potent, specific urate reabsorption inhibitor. We evaluated the effects on ...
  • Harnedy-Rothwell, Pádraigín A.; McLaughlin, Chris M.; Le Gouic, Aurélien V.; Mullen, Ciaran; Parthsarathy, Vadivel; Allsopp, Philip J.; McSorley, Emeir M.; FitzGerald, Richard J.; O’Harte, Finbarr P. M. (Springer, 2021)
    Three synthetic peptides, ILAP, LLAP and MAGVDHI, derived from a Palmaria palmata protein hydrolysate were assessed for their antidiabetic potential in vitro and in vivo. In addition to inhibiting dipeptidyl peptidase-IV ...
  • Khan, Sulaiman; Newport, David; Le Calvé, Stéphane (MDPI, 2021)
    Deep-UV absorption spectrometry for detection of toxic airborne gases, for instance, Benzene, Toluene, Ethylbenzene, and Xylenes (BTEX) has drawn considerable attention owing to its high sensitivity and reliability. However, ...
  • Browne, Leonard D.; Jaouimaa, Fatima-Zahra; Walsh, Cathal; Perez-Ruiz, Fernando; Richette, Paschal; Burke, Kevin; Stack, Austin G. (Elsevier, 2021)
    Background: Elevation of serum uric acid (SUA) is associated with increased mortality; however, controversy exists regarding the nature of the relationship and differences between men and women. We explored relationships ...
  • Gowran, Rosemary Joan; Bray, Nathan; Goldberg, Mary; Rushton, Paula; Saab, Marie Barhouche Abou; Constantine, David; Ghosh, Ritu; Pearlman, Jonathan (MDPI, 2021)
    Introduction: Appropriate wheelchairs are often essential for the health and wellbeing of people with mobility impairments to enhance fundamental freedoms and equal opportunity. To date, provision has mainly focused on ...
  • Yeomans, Caithríona; Comyns, Thomas M.; Cahalan, Róisin Máire; Hayes, Kevin; Costello, Victoria; Warrington, Giles D.; Harrison, Andrew J.; Lyons, Mark; Campbell, Mark J.; Glynn, Liam G.; Kenny, Ian C. (Elsevier, 2019)
    Objectives To investigate factors associated with injury in amateur male and female rugby union players. Design A prospective cohort study. Setting Amateur rugby clubs in Ireland. Participants Male (n = 113) ...
  • Yeomans, Caithríona; Kenny, Ian C.; Cahalan, Róisin Máire; Warrington, Giles D.; Harrison, Andrew J.; Hayes, Kevin; Lyons, Mark; Campbell, Mark J.; Glynn, Liam G.; Comyns, Thomas M. (Elsevier, 2019)
    Objectives: To describe the development, implementation and evaluation of a comprehensive injury surveillance system.Design: The four phases;i) A survey of 58 medical professionals working in amateur rugby.ii) The design ...
  • Yeomans, Caithríona; Kenny, Ian C.; Cahalan, Róisin Máire; Warrington, Giles D.; Harrison, Andrew J.; Purtill, Helen; Lyons, Mark; Campbell, Mark J.; Glynn, Liam G.; Comyns, Thomas M. (SAGE Publications, 2021)
    Background: Rugby union is a physically demanding sport that carries an inherent risk of injury. Despite being a popular and widely played team sport, little is known about injuries occurring across the male and female ...
  • Yeomans, Caithríona; Comyns, Thomas M.; Cahalan, Róisin Máire; Warrington, Giles D.; Harrison, Andrew J.; Hayes, Kevin; Lyons, Mark; Campbell, Mark J.; Kenny, Ian C. (Elsevier, 2018)
    To ascertain current injury surveillance and player education practices in Irish amateur rugby union. Cross-sectional survey. Amateur rugby clubs in Ireland. Medical professionals and rugby coaches of the top 58 amateur ...
  • Anastasiadou, Eleni; Messina, Elena; Sanavia, Tiziana; Mundo, Lucia; Farinella, Federica; Lazzi, Stefano; Megiorni, Francesca; Ceccarelli, Simona; Pontecorvi, Paola; Marampon, Francesco; Di Gioia, Cira Rosaria Tiziana; Perniola, Giorgia; Panici, Pierluigi Benedetti; Leoncini, Lorenzo; Trivedi, Pankaj; Lenzi, Andrea; Marchese, Cinzia (MDPI, 2021)
    Conventional/targeted chemotherapies and ionizing radiation (IR) are being used both as monotherapies and in combination for the treatment of epithelial ovarian cancer (EOC). Several studies show that these therapies might ...
  • Roura, Maria; Dias, Sonia; LeMaster, Joseph W.; MacFarlane, Anne E. (Wiley and Sons Ltd, 2021)
    Context: Migration is one of the most politically pressing issues of the 21st century but migrant health remains an under-researched area. The International Collaboration for Participatory Health Research (ICPHR) working ...
  • Zamboni, Fernanda; Okoroafor, Chinonso; Ryan, Michael P.; Pembroke, Tony J.; Stróżyk, Michał A.; Culebras, Mario; Collins, Maurice N. (Elsevier, 2021)
    Biofilm-related infections and contamination of biomaterials are major problems in the clinic. These contaminations are frequently caused by Staphylococcus aureus and are a pressing issue for implantable devices, catheters, ...
  • Beyene, Kebede; Chan, Amy Hai Yan; Green, James A.; Hermsen, Sander (Ubiquity Press, 2021)
    In the absence of a vaccine, our only defence against the spread and transmission of the coronavirus depends on the behaviours of individuals. In mid-March of 2020, a small group of researchers/collaborators/friends ...
  • Chillón, Palma; Gálvez-Fernández, Patricia; Huertas-Delgado, Francisco Javier; Herrador-Colmenero, Manuel; Barranco-Ruiz, Yaira; Villa-González, Emilio; Aranda-Balboa, María Jesús; Saucedo-Araujo, Romina Gisele; Campos-Garzón, Pablo; Molina-Soberanes, Daniel; Segura-Díaz, José Manuel; Rodríguez-Rodríguez, Fernando; Lara-Sánchez, Amador Jesús; Queralt, Ana; Molina-García, Javier; Bengoechea, Enrique García; Mandic, Sandra (MDPI, 2021)
    “Cycling and Walk to School” (PACO, by its Spanish acronym) that aims to promote cycling to and from school and physical activity (PA) in adolescents. This study will examine the effects of this intervention in cycling and ...
  • O'Neill, Aoife; McFarland, John; Kelly, Dervla (Wiley and Sons Ltd, 2021)
    Objectives: Depression is the most common mental health problem in older adults and untreated is associated with significant burden of illness for patients. This study aimed to examine longitudinal patterns of ...
  • Collins, Maurice N.; Ren, Guang; Young, Kieran; Pina, S.; Reis, Rui L.; Oliveira, J. Miguel (Wiley, 2021)
    Bone tissue engineering (BTE) is a rapidly growing field aiming to create a bio functional tissue that can integrate and degrade in vivo to treat diseased or damaged tissue. It has become evident that scaffold fabrication ...
  • O'Sullivan, Leonard; Duffy, Ed; O'Sullivan, Kevin Jeremiah; Cronin, Úna; Lyons, Emma; O'Sullivan, Leonard; Twomey, Feargal (Australian and New Zealand Society of Palliative Medicine/BMJ Publishing Group, 2021)
    Background We report a case of using 3D printing to create a bespoke eye cover for an 18-year-old man with left maxillary alveolar rhabdomyosarcoma. Further, the patient had proptosis causing chemosis and subsequent ...
  • Grabrucker, Stefanie; Pagano, Jessica; Schweizer, Johanna; Urrutia-Ruiz, Carolina; Schon, Michael; Thome, Kevin; Ehret, Gunter; Grabrucker, Andreas M.; Zhang, Rong; Hengerer, Bastian; Bockmann, Juergen; Verpelli, Chiara; Sala, Carlo; Boeckers, Tobias M. (EMBO Press, 2021)
    Impairments in social relationships and awareness are features observed in autism spectrum disorders (ASDs). However, the under lying mechanisms remain poorly understood. Shank2 is a high-confi dence ASD candidate gene ...
  • McDowell, Cillian P.; Herring, Matthew P.; Lansing, Jeni; Brower, Cassandra S; Meyer, Jacob D. (Frontiers Media, 2021)
    Objectives: To examine associations of changing employment conditions, specifically switching to working from home (WFH) or job loss, with mental health, using data collected during the COVID-19 pandemic. Methods: Data ...
  • Gordon, Brett R.; McDowell, Cillian P.; Lyons, Mark; Herring, Matthew P. (Elsevier, 2021)
    Introduction: The objective of this randomized controlled trial (RCT) was to quantify the effects of eight weeks of World Health Organization and American College of Sports Medicine guidelines-based resistance exercise ...

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