Browsing Research Institutes by Title

Now showing items 1-20 of 144

Age and sex related differences in shoulder abduction fatigue

Collins, John D.; O'Sullivan, Leonard (BioMed Central, 2018)

Background: Injury prevalence data commonly indicate trends of higher rates of work-related musculoskeletal disorders in older workers over their younger counterparts, and for females more than males. The purpose of ...
Altered intestinal morphology and microbiota composition in the autism spectrum disorders associated SHANK3 mouse model

Sauer, Ann Katrin; Bockmann, Juergen; Steinestel, Konrad; Boeckers, Tobias M.; Grabrucker, Andreas M. (MDPI, 2019)

Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders characterized by deficits in social interaction and communication, and repetitive behaviors. In addition, co-morbidities such as gastro-intestinal ...
Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: an integrative review.

O'Reilly, Pauline; Lee, Siew Hwa; O'Sullivan, Madeleine; Cullen, Walter; Kennedy, Catriona; MacFarlane, Anne E. (2017)

Interdisciplinary team working is of paramount importance in the reform of primary care in order to provide cost-effective and comprehensive care. However, international research shows that it is not routine practice in ...
Assessment of an active industrial exoskeleton to aid dynamic lifting and lowering manual handling tasks

Huysamen, Kirsten; de Looze, Michiel P.; Bosch, Tim; Ortiz, Jesús; Toxiri, Stefano; O'Sullivan, Leonard (Elsevier, 2018)

The aim of this study was to evaluate the effect of an industrial exoskeleton on muscle activity, perceived musculoskeletal effort, measured and perceived contact pressure at the trunk, thighs and shoulders, and subjective ...
Association of height with elevated mortality risk in ESRD: variation by race and gender

Elsayed, Mohamed E.; Ferguson, John P.; Stack, Austin G. (Dove Medical Press, 2016)

The association of adult height withmortality has been extensively investigated in the general population, but little is known about this relationship among dialysis patients. We explored the relationship between height ...
Associations of self-reported physical activity and depression in 10,000 irish adults across harmonised datasets: a DEDIPAC-study

Mc Dowell, Cillian P.; Carlin, Angela; Capranica, Laura; Dillon, Christina; Harrington, Janas M.; Lakerveld, Jeroen; Loyen, Anne; Chun Man Ling, Fiona; Brug, Johannes; MacDonncha, Ciaran; Herring, Matthew P. (BioMed Central, 2018)

Background: Depression is a prevalent, debilitating, and often recurrent mood disorder for which successful firstline treatments remains limited. The purpose of this study was to investigate the cross-sectional ...
ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis

Collins, Catríona M.; Malacrida, Beatrice; Burke, Colin; Kiely, Patrick A.; Dunleavy, Elaine M. (Nature Publishing Group, 2018)

The histone H3 variant CENP-A epigenetically defines the centromere and is critical for chromosome segregation. Here we report an interaction between CENP-A and subunits of the mitochondrial ATP synthase complex in the ...
Bioprospecting for antithrombotic polar lipids from salmon, herring, and boarfish by-products

Tsoupras, Alexandros; O'Keeffe, Eoin; Lordan, Ronan; Redfern, Shane; Zabetakis, Ioannis (MDPI, 2019)

Marine polar lipids (PLs) have exhibited promising cardioprotection. In this study, marine by-products such as salmon heads (SHs), their brain, eyes and main optic nerves (SBEON),and head-remnants after SBEON removal ...
Brain lateralization in mice is associated with zinc signaling and altered in prenatal zinc deficient mice that display features of autism spectrum disorder

Grabrucker, Stefanie; Haderspeck, Jasmin C.; Sauer, Ann Katrin; Kittelberger, Nadine; Asoglu, Harun; Abaei, Alireza; Rasche, Volker; Schon, Michael; Boeckers, Tobias M.; Grabrucker, Andreas M. (Frontiers Media, 2018)

A number of studies have reported changes in the hemispheric dominance in autism spectrum disorder (ASD) patients on functional, biochemical, and morphological level. Since asymmetry of the brain is also found in many ...
Can different patient satisfaction survey methods yield consistent results? Comparison of three surveys

Cohen, Geoff; Forbes, John F.; Garraway, Michael (BMJ Publishing Group, 1996)

Objective-To examine the consistency of survey estimates ofpatient satisfaction with interpersonal aspects of hospital experience. Design-Interview and postal surveys, evidence from three independent population surveys ...
Caregiving alters immunity and stress hormones: a review of recent research

Whittaker, Anna C.; Gallagher, Stephen (Elsevier, 2019)

Older caregivers of dementia patients have been studied as a model of chronic stress influencing psychological and physical well-being and the function of the immune system. These immune decrements can relate to altered ...
A cell-based evaluation of a non-essential amino acid formulation as a non-bioactive control for activation and stimulation of muscle protein synthesis using ex vivo human serum

Patel, Bijal; Pauk, Martina; Amigo-Benavent, Miryam; Nongonierma, Alice B.; Fitzgerald, Richard J.; Jakeman, Philip M.; Carson, Brian P. (Public Library of Science, 2019)

The purpose of this study was to compare the effect of treating skeletal muscle cells with media conditioned by postprandial ex vivo human serum fed with either isonitrogenous Non-Essential Amino Acid (NEAA) or a whey ...
Changes in peristomal skin condition and user experience of a novel ostomy barrier ring with assisted flow: a 6-week feasibility study

Hunt, Rhona; Kelleher, Kevin; Coffey, Calvin J.; Clarke-Moloney, Mary; Ahern, Mary; Conway, Elaine; Hannigan, Ailish; Erwin-Toth, Paula; O'Sullivan, Leonard (Lippincott, Williams & Wilkins, 2018)

PURPOSE: This purpose of this study was to evaluate a novel barrier ring with an assisted flow mechanism by assessing changes in peristomal moisture-associated skin damage (MASD) and perceptions of comfort, security, ...
Characterisation of human urethral rupture thresholds for urinary catheter inflation related injuries

Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Hess, J.; Walsh, Michael T. (Elsevier, 2018)

Data on urethral catheter related injuries is sparse. In this study we aimed to characterise urethral diametric strain and urinary catheter inflation pressure thresholds that precede human urethral trauma during urethral ...
Clinical effectiveness of non-surgical interventions for primary frozen shoulder: A Systematic review

Lowe, Catherine Minns; Barrett, Eva; McCreesh, Karen; De Burca, Neasa; Lewis, Jeremy S. (Foundation for Rehabilitation information, 2019)

Frozen shoulder commonly affects people aged around 50 years and is associated with substantial levels of shoulder pain and stiffness that may last for many years. Many people with frozen shoulder report that simple ...
Clinical evaluation of a safety-device to prevent urinary catheter inflation related injuries

Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Forde, James C.; Walsh, Michael T. (Elsevier, 2018)

OBJECTIVE: To evaluate the feasibility of a novel “safety-valve” device for preventing catheter related urethral trauma during urethral catheterization (UC). To assess the opinions of clinicians on the performance of the ...
Cognitive functional therapy compared with a group-based exercise and education intervention for chronic low back pain: a multicentre randomised controlled trial (RCT)

O'Keeffe, Mary; O'Sullivan, Peter B.; Purtill, Helen; Bargary, Norma; O'Sullivan, Kieran (BMJ Publishing Group, 2019)

Background: One-size-fits-all interventions reduce chronic low back pain (CLBP) a small amount. An individualised intervention called cognitive functional therapy (CFT) was superior for CLBP compared with manual therapy ...
Collagen induces a more proliferative, migratory and chemoresistant phenotype in head and neck cancer via DDR1

Ling Lai, Sook; Leng Tan, May; Hollows, Robert J.; Robinson, Max; Ibrahim, Maha; Margielewska, Sandra; Parkinson, E. Kenneth; Ramanathan, Anand; Binti Zain, Rosnah; Mehanna, Hisham; Spruce, Rachel J.; Wei, Wenbin; Chung, Ivy; Murray, Paul G.; Fah Yap, Lee; Paterson, Ian C. (MDPI, 2019)

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and includes squamous cell carcinomas of the oropharynx and oral cavity. Patient prognosis has remained poor for decades and molecular ...
Comparisons in screen-time behaviours among adolescents with and without long-term illnesses or disabilities: results from 2013/14 HBSC study

Ng, Kwok W.; Augustine, Lilly; Inchley, Jo (MDPI, 2018)

Reducing sedentary behaviours can help prevent non-communicable diseases, particularly among young adolescents with long term illnesses or disabilities (LTID). Much of young people’s voluntary sedentary time is related ...
Computerized cuff pressure algometry as guidance for circumferential tissue compression for wearable soft robotic applications: a systematic review

Kermavnar, Tjaša; Power, Valerie; de Eyto, Adam; O'Sullivan, Leonard (Mary Ann Liebert, 2017)

In this article, we review the literature on quantitative sensory testing of deep somatic pain by means of computerized cuff pressure algometry (CPA) in search of pressure-related safety guidelines for wearable soft exoskeleton ...

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