Browsing Research Institutes by Title

Now showing items 1-20 of 207

Age and sex related differences in shoulder abduction fatigue

Collins, John D.; O'Sullivan, Leonard (BioMed Central, 2018)

Background: Injury prevalence data commonly indicate trends of higher rates of work-related musculoskeletal disorders in older workers over their younger counterparts, and for females more than males. The purpose of ...
Altered intestinal morphology and microbiota composition in the autism spectrum disorders associated SHANK3 mouse model

Sauer, Ann Katrin; Bockmann, Juergen; Steinestel, Konrad; Boeckers, Tobias M.; Grabrucker, Andreas M. (MDPI, 2019)

Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders characterized by deficits in social interaction and communication, and repetitive behaviors. In addition, co-morbidities such as gastro-intestinal ...
Assessing the facilitators and barriers of interdisciplinary team working in primary care using normalisation process theory: an integrative review.

O'Reilly, Pauline; Lee, Siew Hwa; O'Sullivan, Madeleine; Cullen, Walter; Kennedy, Catriona; MacFarlane, Anne E. (2017)

Interdisciplinary team working is of paramount importance in the reform of primary care in order to provide cost-effective and comprehensive care. However, international research shows that it is not routine practice in ...
Assessing the impact of a matching adjusted indirect comparison in a bayesian network meta analysis

Leahy, Joy; Walsh, Cathal Dominic (Wiley and Sons Ltd., 2019)

if IPD is available for some or all trials in an NMA, then incorporating this IPD into an NMA is routinely considered to be preferable. However, the situation often arises where a researcher has IPD for trials concerning ...
Assessment of an active industrial exoskeleton to aid dynamic lifting and lowering manual handling tasks

Huysamen, Kirsten; de Looze, Michiel P.; Bosch, Tim; Ortiz, Jesús; Toxiri, Stefano; O'Sullivan, Leonard (Elsevier, 2018)

The aim of this study was to evaluate the effect of an industrial exoskeleton on muscle activity, perceived musculoskeletal effort, measured and perceived contact pressure at the trunk, thighs and shoulders, and subjective ...
The association between the acute: chronic workload ratio and injury and its application in team sports: a systematic review

Griffin, Alan; Kenny, Ian C.; Comyns, Thomas M.; Lyons, Mark (Springer, 2019)

There has been a recent increase in research examining training load as a method of mitigating injury risk due to its known detrimental effects on player welfare and team performance. The acute:chronic workload ratio (ACWR) ...
Association of height with elevated mortality risk in ESRD: variation by race and gender

Elsayed, Mohamed E.; Ferguson, John P.; Stack, Austin G. (Dove Medical Press, 2016)

The association of adult height withmortality has been extensively investigated in the general population, but little is known about this relationship among dialysis patients. We explored the relationship between height ...
Associations of self-reported physical activity and depression in 10,000 irish adults across harmonised datasets: a DEDIPAC-study

Mc Dowell, Cillian P.; Carlin, Angela; Capranica, Laura; Dillon, Christina; Harrington, Janas M.; Lakerveld, Jeroen; Loyen, Anne; Chun Man Ling, Fiona; Brug, Johannes; MacDonncha, Ciaran; Herring, Matthew P. (BioMed Central, 2018)

Background: Depression is a prevalent, debilitating, and often recurrent mood disorder for which successful firstline treatments remains limited. The purpose of this study was to investigate the cross-sectional ...
The associations of sugar-sweetened, artificially sweetened and naturally sweet juices with all-cause mortality in 198,285 UK Biobank participants: a prospective cohort study

Anderson, Jana J.; Gray, Stuart R; Welsh, Paul; Mackay, Daniel F.; Celis-Morales, Carlos A.; Lyall, Donald M.; Forbes, John F.; Sattar, Naveed; Gill, Jason M. R.; Pell, Jill P. (BMC, 2020)

Background: Recent efforts to address the obesity epidemic have focused on sugar consumption, especially sugar-sweetened beverages. However, sugar takes many forms, is only one contributor to overall energy consumption and ...
ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis

Collins, Catríona M.; Malacrida, Beatrice; Burke, Colin; Kiely, Patrick A.; Dunleavy, Elaine M. (Nature Publishing Group, 2018)

The histone H3 variant CENP-A epigenetically defines the centromere and is critical for chromosome segregation. Here we report an interaction between CENP-A and subunits of the mitochondrial ATP synthase complex in the ...
Bioprospecting for antithrombotic polar lipids from salmon, herring, and boarfish by-products

Tsoupras, Alexandros; O'Keeffe, Eoin; Lordan, Ronan; Redfern, Shane; Zabetakis, Ioannis (MDPI, 2019)

Marine polar lipids (PLs) have exhibited promising cardioprotection. In this study, marine by-products such as salmon heads (SHs), their brain, eyes and main optic nerves (SBEON),and head-remnants after SBEON removal ...
Brain lateralization in mice is associated with zinc signaling and altered in prenatal zinc deficient mice that display features of autism spectrum disorder

Grabrucker, Stefanie; Haderspeck, Jasmin C.; Sauer, Ann Katrin; Kittelberger, Nadine; Asoglu, Harun; Abaei, Alireza; Rasche, Volker; Schon, Michael; Boeckers, Tobias M.; Grabrucker, Andreas M. (Frontiers Media, 2018)

A number of studies have reported changes in the hemispheric dominance in autism spectrum disorder (ASD) patients on functional, biochemical, and morphological level. Since asymmetry of the brain is also found in many ...
Building resources in caregivers: feasibility of a brief writing intervention to increase benefit finding in caregivers

Gallagher, Stephen; O'Sullivan, Liam; Hughes, Zoe; O'Connell, Brenda H. (Wiley and Sons Ltd, 2020)

Health and Well-Being published by John Wiley & Sons Ltd on behalf of International Association of Applied Psychology The Building Resources in Caregivers (BRiC) is a pilot feasibility trial that compared the effects of ...
Can different patient satisfaction survey methods yield consistent results? Comparison of three surveys

Cohen, Geoff; Forbes, John F.; Garraway, Michael (BMJ Publishing Group, 1996)

Objective-To examine the consistency of survey estimates ofpatient satisfaction with interpersonal aspects of hospital experience. Design-Interview and postal surveys, evidence from three independent population surveys ...
Caregiving alters immunity and stress hormones: a review of recent research

Whittaker, Anna C.; Gallagher, Stephen (Elsevier, 2019)

Older caregivers of dementia patients have been studied as a model of chronic stress influencing psychological and physical well-being and the function of the immune system. These immune decrements can relate to altered ...
A cell-based evaluation of a non-essential amino acid formulation as a non-bioactive control for activation and stimulation of muscle protein synthesis using ex vivo human serum

Patel, Bijal; Pauk, Martina; Amigo-Benavent, Miryam; Nongonierma, Alice B.; Fitzgerald, Richard J.; Jakeman, Philip M.; Carson, Brian P. (Public Library of Science, 2019)

The purpose of this study was to compare the effect of treating skeletal muscle cells with media conditioned by postprandial ex vivo human serum fed with either isonitrogenous Non-Essential Amino Acid (NEAA) or a whey ...
The change of pain classes over time: a latent transition analysis

O'Neill, Aoife; O'Sullivan, Kieran; O'Keeffe, Mary; Walsh, Cathal Dominic; Purtill, Helen (Wiley and Sons Ltd.,, 2020)

Background Pain is common in older adults, and associated with increased morbidity and reduced quality of life. Recent research has highlighted different classes of older adults with pain, each with differing impacts ...
Changes in peristomal skin condition and user experience of a novel ostomy barrier ring with assisted flow: a 6-week feasibility study

Hunt, Rhona; Kelleher, Kevin; Coffey, Calvin J.; Clarke-Moloney, Mary; Ahern, Mary; Conway, Elaine; Hannigan, Ailish; Erwin-Toth, Paula; O'Sullivan, Leonard (Lippincott, Williams & Wilkins, 2018)

PURPOSE: This purpose of this study was to evaluate a novel barrier ring with an assisted flow mechanism by assessing changes in peristomal moisture-associated skin damage (MASD) and perceptions of comfort, security, ...
Characterisation of human urethral rupture thresholds for urinary catheter inflation related injuries

Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Hess, J.; Walsh, Michael T. (Elsevier, 2018)

Data on urethral catheter related injuries is sparse. In this study we aimed to characterise urethral diametric strain and urinary catheter inflation pressure thresholds that precede human urethral trauma during urethral ...
Characterising the prognostic potential of HLA‑DR during colorectal cancer development

Dunne, Margaret R.; Phelan, James J; Michielsen, Adriana J.; Maguire, Aoife A.; Dunne, Cara; Martin, Petra; Noonan, Sinead; Tosetto, Miriam; Geraghty, Robert; Fennelly, David; Sheahan, Kieran; Ryan, Elizabeth J.; O’Sullivan, Jacintha (Springer, 2020)

HLA-DR, an MHC class II molecule that mediates antigen presentation, is a favourable prognostic indicator in colorectal cancer (CRC). However, the dynamics and location of HLA-DR expression during CRC development are ...

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