Stack, Austin G.; Li, Xia; Kaballo, Mohamed; Elsayed, Mohamed E.; Johnson, Howard; Murray, Patrick T.; Saran, Rajiv; Browne, Leonard D.(Oxford University Press, 2018)
Background. Complete ascertainment of the true rates of acute
kidney injury (AKI) and emerging trends are essential for planning
of preventive strategies within health systems.
Methods. We conducted a retrospective ...
Collins, Catríona M.; Malacrida, Beatrice; Burke, Colin; Kiely, Patrick A.; Dunleavy, Elaine M.(Nature Publishing Group, 2018)
The histone H3 variant CENP-A epigenetically defines the centromere and is critical for
chromosome segregation. Here we report an interaction between CENP-A and subunits of
the mitochondrial ATP synthase complex in the ...
Collins, John D.; O'Sullivan, Leonard(BioMed Central, 2018)
Background: Injury prevalence data commonly indicate trends of higher rates of work-related musculoskeletal
disorders in older workers over their younger counterparts, and for females more than males. The purpose of ...
Background: Network meta-analysis (NMA) allows for the estimation of comparative effectiveness of treatments
that have not been studied in head-to-head trials; however, relative treatment effects for all interventions can ...
Hagmeyer, Simone; Sauer, Ann Katrin; Grabrucker, Andreas M.(Frontiers Media, 2018)
The loss of one copy of SHANK3 (SH3 and multiple ankyrin repeat domains 3) in humans highly contributes to Phelan McDermid syndrome (PMDS). In addition, SHANK3 was identified as a major autism candidate gene. Interestingly, ...
Vilella, Antonietta; Belletti, Daniela; Sauer, Ann Katrin; Hagmeyer, Simone; Sarowar, Tasnuva; Masoni, Martina; Stasiak, Natalia; Mulvihill, John J.; Ruozi, Barbara; Forni, Flavio; Vandelli, Maria Angela; Tosi, Giovanni; Zoli, Michele; Grabrucker, Andreas M.(Elsevier, 2017)
A local dyshomeostasis of zinc ions in the vicinity of amyloid aggregates has been proposed in Alzheimer’s disease (AD) due to the sequestration of zinc in senile plaques. While an increase in zinc levels may promote the ...
Objective: Although physical activity (PA) is associated with a reduction of a wide range of sleep problems,
it remains uncertain whether complying with the international guidelines of 150 min of moderate
to vigorous PA ...
Kumar A. U., Arun; Browne, Leonard D.; Li, Xia; Adeeb, Fahd; Perez-Ruiz, Fernando; Fraser, Alexander D.; Stack, Austin G.(Public Library of Science, 2018)
Background
Elevated serum uric acid (sUA) concentrations are common in the general population and
are associated with chronic metabolic conditions and adverse clinical outcomes. We evaluated
secular trends in the burden ...
Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Forde, James C.; Walsh, Michael T.(Elsevier, 2018)
OBJECTIVE: To evaluate the feasibility of a novel “safety-valve” device for preventing catheter related urethral
trauma during urethral catheterization (UC). To assess the opinions of clinicians on the performance
of the ...
Sheehan, Rachel B.; Herring, Matthew P.; Campbell, Mark J.(Elsevier, 2018)
Objectives: This study characterised mental health, motivation, and their interrelations among 38 elite studentathletes
over a 13-week season, while monitoring and considering the influence of their athletic and ...
Belletti, Daniela; Grabrucker, Andreas M.; Pederzoli, Francesca; Menrath, Isabel; Vandelli, Maria Angela; Tosi, Giovanni; Duskey, Thomas Jason; Forni, Flavio; Ruozi, Barbara(Elsevier, 2018)
Restoration of the Chol homeostasis in the Central Nervous System (CNS) could be beneficial for the treatment of Huntington's Disease (HD), a progressive, fatal, adult-onset, neurodegenerative disorder. Unfortunately, Chol ...
Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Hess, J.; Walsh, Michael T.(Elsevier, 2018)
Data on urethral catheter related injuries is sparse. In this study we aimed to characterise urethral diametric strain and urinary catheter inflation pressure thresholds that precede human urethral trauma during urethral ...
The aim of this study was to evaluate the effect of an industrial exoskeleton on muscle activity, perceived musculoskeletal effort, measured and perceived contact pressure at the trunk, thighs and shoulders, and subjective ...
Background: Central venous catheters (CVC) are associated with substantial morbidity and mortality among patients undergoing haemodialysis (HD), yet they are frequently used as the primary vascular access for many patients ...
The present study investigated the possible interaction between life events stress and personality in predicting cardiovascular stress responses. Participants (N = 184) completed psychometric measures of life event stress ...
Specific patient cohorts are at increased risk of vascular calcification. Functional matrix-gla
protein (MGP), a tissue-derived vitamin K dependent protein, is reported to be an important inhibitor of vascular calcification ...
O'Riordan, David; Elodie Aubert, Carole; Walsh, Kieran A.; Van Dorland, Anette; Rodondi, Nicolas; Du Puy, Robert S.; Poortvliet, Rosalinde K E.; Gussekloo, Jacobijn; Sinnott, Carol; Byrne, Stephen; Galvin, Rose; Jukema, J Wouter; Mooijaart, Simon P.; Baumgartner, Christine; McCarthy, Vera; Walsh, Elaine K.; Collet, Tinh-Hai; Dekkers, Olaf M.; Blum, Manuel R.; Kearney, Patricia M.(BMJ Publishing Group, 2018)
Objectives To estimate and compare the prevalence and type of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) among communitydwelling
older adults (≥65 years) enrolled to a clinical ...
Background: Despite the problem of inadequate recruitment to randomised trials, there is little evidence to guide researchers on decisions about how people are effectively recruited to take part in trials. The PRioRiTy ...
Adamson, Philip D.; Hunter, Amanda; Madsen, Debbie M.; Shah, Anoop S.V.; McAllister, David A.; Pawade, Tania A.; Williams, Michelle C.; Berry, Colin; Boon, Nicholas A.; Flather, Marcus; Forbes, John F.; McLean, Scott; Roditi, Giles; Timmis, Adam D.; van Beek, Edwin J.R.; Dweck, Marc R.; Mickley, Hans; Mills, Nicholas L.; Newby, David E.(American Heart Association, 2018)
Background: We determined whether high-sensitivity cardiac troponin I can improve the estimation of the pretest probability for obstructive coronary artery disease (CAD) in patients with suspected stable angina.
Methods ...
Ryan, Aine; Murphy, Catriona; Boland, Fiona; Galvin, Rose; Smith, Susan M.(Oxford University Press on behalf of The Gerontological Society of America, 2018)
Background: Multimorbidity is recognized internationally as having a serious impact on health outcomes. It is associated with reduced quality
of life, increased health care utilization, and future functional decline. ...