Interdisciplinary team working in primary care is a key policy goal across healthcare jurisdictions. The National Primary Care Strategy (2001) in Ireland is a top down policy for primary healthcare reform, which prioritised ...
Abbas, Raja Manzar; Carroll, Noel; Richardson, Ita; Beecham, Sarah(2018)
Being able to trust technology is of vital importance to its potential users. This is particularly true within the healthcare sector where lives increasingly depend on the correct application of technology to support ...
Cunnane, Connor V.; Cunnane, Eoghan M.; Moran, Daniel T.; Walsh, Michael T.(Wiley and Sons Ltd, 2019)
Areas of disturbed shear that develop following arteriovenous fistula (AVF) creation are believed to trigger the onset of intimal hyperplasia (IH), leading to AVF dysfunction. The presence of helical flow can suppress the ...
Van de Ven Pepijn; Araya Ricardo; P de Paula Couto Maria Clara.; Henrique Maiara Garcia; Meere, Damien; Vilela Mendes Ana; Peters Tim J; Seabra Antônio; Franzin Renato M; Carvalho Pereda Paula; Scazufca, Marcia(2019)
Background: There is a considerable shortfall in specialized health care professionals worldwide to deliver health services, and this shortfall is especially pronounced in low-middle-income countries. This has led to the ...
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide and includes squamous cell carcinomas of the oropharynx and oral cavity. Patient prognosis has remained poor for decades and molecular ...
Patel, Bijal; Pauk, Martina; Amigo-Benavent, Miryam; Nongonierma, Alice B.; Fitzgerald, Richard J.; Jakeman, Philip M.; Carson, Brian P.(Public Library of Science, 2019)
The purpose of this study was to compare the effect of treating skeletal muscle cells with
media conditioned by postprandial ex vivo human serum fed with either isonitrogenous Non-Essential Amino Acid (NEAA) or a whey ...
Ntemiri, Alexandra; Ribiere, Celine; Stanton, Catherine; Ross, R Paul; O'Connor, Eibhís; O'Toole, Paul W.(American Chemical Society, 2019)
Prebiotics may improve ageing-related dysbiosis. Milk is a source of nutrients including oligosaccharides whose prebiotic potential remains largely unexplored. We used a murine model to explore the effect of milk products ...
Background: One-size-fits-all interventions reduce chronic low back pain (CLBP) a small amount. An individualised intervention called cognitive functional therapy (CFT) was superior for CLBP compared with manual therapy ...
Adamson, Philip D.; Williams, Michelle C.; Dweck, Marc R.; Mills, Nicholas L.; Boon, Nicholas A.; Daghem, Marwa; Bing, Rong; Moss, Alastair J.; Mangion, Kenneth; Flather, Marcus; Forbes, John F.; Hunter, Amanada; Norrie, John; Shah, Anoop S.V.; Timmis, Adam D.; van Beek, Edwin J.R.; Ahmandi, Amir A.; Leipsic, Jonathon; Narula, Jagat; Newby, David E.; Roditi, Giles; McAllister, David A.; Berry, Colin(Elsevier, 2019)
BACKGROUND Within the SCOT-HEART (Scottish COmputed Tomography of the HEART Trial) trial of patients with
stable chest pain, the use of coronary computed tomography angiography (CTA) reduced the rate of death from ...
Summer, Rachel C.; Gallagher, Stephen(Taylor and Francis, 2017)
Objective: Unemployment is a type of chronic stressor that impacts human health. The reasons for how the stress of unemployment affect health is still a matter of discussion. One of the pathways from chronic stress to ill ...
2
Unemployment has been associated with poorer health, but few studies have examined the biological mechanisms that confer these health decrements. Further, no studies to date have examined differences across employment ...
Introduction Stroke is among the leading causes of death and disability worldwide. Poststroke cognitive impairment is a common sequela of stroke. The burden of cognitive impairment poststroke has significant impacts on the ...
McMahon, Grace; Creaven, Ann-Marie; Gallagher, Stephen(Wiley and Sons Ltd, 2019)
To understand the influence of social relationships on cardiovascular responses to stress, the present study investigated perceived affectionate support as a mediating variable explaining the association between specific ...
The accumulation of amyloid β (Aβ) triggers a cascade of toxic events in Alzheimer’s
disease (AD). The KLVFF peptide can interfere with Aβ aggregation. However, the peptide suffers from poor bioavailability and the inability ...
McCann, Angela; Jeffery, Ian B; Ouliass, Bouchra; Ferland, Guylaine; Fu, Xueyen; Booth, Sarah L; Tran, Tam T.T.; O’Toole, Paul W; O'Connor, Eibhlís M.(Oxford University Press, 2019)
ackground: Vitamin K has multiple important physiological roles, including blood coagulation and beneficial effects on myelin integrity in the brain. Some intestinal microbes possess the genes to produce vitamin K in the ...
McCrory, Cathal; Leahy, Siobhan; Ribeiro, Ana Isabel; Fraga, Silvia; Barros, Henrique; Avendano, Mauricio; Vineis, Paolo; Layte, Richard(Wiley and Sons Ltd, 2019)
Background
Social inequalities in the prevalence of childhood overweight and obesity are well‐established, but less is known about when the social gradient first emerges and how it evolves across childhood and ...
Herring, Matthew P.; Kline, Christopher E.; O'Connor, Patrick J.(Elsevier, 2015)
Statement of the problem
Generalized Anxiety Disorder (GAD) and disturbed sleep are prevalent, debilitating, and frequently comorbid problems for which successful treatment remains limited. Exercise can promote sleep but ...
Background:
Patients with end-stage kidney disease (ESKD) on dialysis were excluded from clinical trials of direct oral anticoagulants for atrial fibrillation (AF). Recent data have raised concerns regarding the safety ...
Background: Older people are frequent emergency department (ED) users who present with complex issues that are linked to poorer health outcomes following the index visit, often have increased ED length of stay, and tend ...
Background: Cancer survivorship in Ireland is increasing in both frequency and longevity. However, a significant proportion of cancer survivors are overweight. This has negative implications for long-term health outcomes, ...