University of Limerick Institutional Repository

Browsing Research Institutes, Centres and Units by Subject "zinc"

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Browsing Research Institutes, Centres and Units by Subject "zinc"

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  • De Benedictis, Chiara A.; Raab, Andrea; Ducie, Ellen; Howley, Shauna; Feldmann, Joerg; Grabrucker, Andreas M. (MDPI, 2020)
    The essential trace metals iron, zinc, and copper have a significant physiological role in healthy brain development and function. Especially zinc is important for neurogenesis, synaptogenesis, synaptic transmission and ...
  • Pandey, Mukesh K.; Grabrucker, Andreas M.; Mehta, Sunil Q.; Harvey, Robert J. (Frontiers Media, 2022)
    Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental disorder with a complex etiology that appears to be a mixture of underlying environmental and genetic risk factors. Among the environmental risk factors ...
  • De Benedictis, Chiara A.; Vilella, Antonietta; Grabrucker, Andreas M. (2019)
    The extracellular aggregation of insoluble protein deposits of amyloid-β (Aβ) into plaques and the hyperphosphorylation of the intracellular protein tau leading to neurofibrillary tangles are the main pathological hallmarks ...
  • Hagmeyer, Simone; Cristóvão, Joana S.; Mulvihill, John J.E.; Boeckers, Tobias M.; Gomes, Cláudio M.; Grabrucker, Andreas M. (Frontiers Media, 2018)
    Neuronal metal ions such as zinc are essential for brain function. In particular synaptic processes are tightly related to metal and protein homeostasis, for example through extracellular metal-binding proteins. One such ...

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