• Risk stratification in heart failure decompensation in the community: HEFESTOS score 

  Verdu-Rotellar, José María; Abellana, Rosa; Vaillant-Roussel, Helene; Jevsek, Lea Gril; Assenova, Radost; Lazic, Djurdjica Kasuba; Torsza, Peter; Glynn, Liam G.; Lingner, Heidrun; Demurtas, Jacopo; Thulesius, Hans; Muñoz, Miguel Angel; Miguel Angel (Wiley and Sons Ltd, 2021)

  Aims Because evidence regarding risk stratification predicting prognosis of patients with heart failure (HF) decompensation attended in primary care is lacking, we developed and externally validated a model to forecast ...
• Dysregulation of metabolic pathways in circulating natural killer cells isolated from inflammatory bowel disease patients 

  Bittencourt, Vanessa Zaiatz; Jones, Fiona; Tosetto, Miriam; Doherty, Glen A.; Ryan, Elizabeth J. (Oxford University Press, 2021)

  Background and Aims: Inflammatory bowel diseases [IBD], comprising Crohn’s disease [CD] and ulcerative colitis [UC], are chronic conditions characterized by severe dysregulation of innate and adaptive immunity resulting ...
• A physiotherapy-led transition to home intervention for older adults following emergency department discharge: protocol for a pilot feasibility randomised controlled trial 

  Conneely, Mairéad; Leahy, Aoife; O'Connor, Margaret; Barry, Louise; Corey, Gillian; Griffin, Anne; O'Shaughnessy, Íde; O'Carroll, Ida; Leahy, Siobhán; Trépel, Dominic; Ryan, Damian; Robinson, Katie; Galvin, Rose (BMC, 2022)

  Background: Older adults frequently attend the emergency department (ED) and experience high rates of adverse outcomes following ED presentation including functional decline, ED re-presentation and unplanned hospital ...
• Antidepressant medication prescribing patterns in Irish General Practice from 2016 to 2020 to assess for long term use 

  McCool, Aoibhin; Lukas, Kurt; Hayes, Peter; Kelly, Dervla (Springer, 2021)

  Background/aims The aim of this study was to identify the trends in antidepressant (AD) medication use in two Irish general practices over a 5-year period, 2016 to 2020. The rationale for this study is attributed to the ...
• Participatory approaches in the context of research into workplace health promotion to improve physical activity levels and reduce sedentary behaviour among office-based workers: protocol for a scoping review 

  Buffey, Aidan John; Carson, Brian P.; Donnelly, Alan; Salsberg, Jon (BMJ, 2021)

  Physical activity (PA) workplace health promotion (WHP) interventions have traditionally used a top-down research approach where end-users are considered as passive subjects. Whereas participatory research (PR) involves ...
• Emergency general surgery during the COVID-19 pandemic 

  O'Callaghan, M.; Toale, C.; Sheikhi, A.; Scanlon, T.; Kavanagh, Eamon G.; Coffey, Calvin J.; Cunningham, R.M. (Irish Medical Organization, 2021)

  Aims The global COVID-19 pandemic has impacted upon the delivery of surgical services worldwide. This study investigated its impact on emergency general and vascular surgical activity at a tertiary level hospital in ...
• A narrative review of the role of psychological skills and characteristics in navigating the pathway to professional rugby union 

  McAuliffe, Julieanne; Lavallee, David; Campbell, Mark J. (Routledge Taylor & Francis, 2021)

  To overcome the challenges associated with navigating the talent development pathway to professional rugby, players must possess certain psychological skills and characteristics (PSCs), e.g., motivation, confidence, and ...
• ‘The System is not set up for the benefit of women’: women’s experiences of decision-making during pregnancy and birth in Ireland 

  Huschke, Susann (SAGE, 2021)

  In this article, I draw on in-depth qualitative interviews with 23 women, conducted in 2019/2020, focusing on their involvement in decision-making during pregnancy and birth. The study is located in Ireland, where comparably ...
• Association between work status and depression in informal caregivers: a collaborative modelling approach 

  O'Neill, Aoife; Gallagher, Stephen; Hannigan, Ailish; Robinson, Katie (Oxford University Press, 2021)

  Background: Care is regularly provided on an informal basis by family and friends and it is well established that caregivers experience high rates of depression. The majority of research on caregivers tends to focus on ...
• Obtaining consensus on core components of stuttering intervention for adults: An e-delphi survey with key stakeholders 

  Connery, Amy; Yaruss, Scott; Lomheim, Holly; Loucks, Torrey M.; Galvin, Rose; McCurtin, Arlene (John Wiley & Sons, 2021)

  Background: Evidence-based practice involves the synthesis of multiple forms of evidence to inform clinical decision-making and treatment evaluation. Practice- and patient-based evidence are two forms of evidence that are ...
• A cluster analysis of device-measured physical activity behaviours and the association with chronic conditions, multi-morbidity and healthcare utilisation in adults aged 45 years and older 

  O'Regan, Andrew; Hannigan, Ailish; Glynn, Liam G.; Bengoechea, Enrique Garcia; Donnelly, Alan; Hayes, Grainne; Murphy, Andrew W.; Clifford, Amanda M.; Gallagher, Stephen; Woods, Catherine B. (Elsevier, 2021)

  Most adults do not meet physical activity guidelines with negative implications for health. The aim of this study was to profile adults using multiple physical activity behaviours and to investigate associations with ...
• A novel mechanism of ataxia telangiectasia mutated mediated regulation of chromatin remodeling in hypoxic conditions 

  Likhatcheva, Maria; Gieling, Roben G.; Brown, James A.L.; Demopoulos, Constantinos A.; Williams, Kaye J. (Frontiers Media, 2021)

  The effects of genotoxic stress can be mediated by activation of the Ataxia Telangiectasia Mutated (ATM) kinase, under both DNA damage-dependent (including ionizing radiation), and independent (including hypoxic stress) ...
• A scoping review of occupational therapy interventions in the treatment of people with substance use disorders 

  Ryan, Deirdre Anne; Boland, Pauline (Emerald Publishing Limited, 2021)

  Purpose – Diagnosis of substance use disorders and addictive behaviours are growing worldwide. It is timely to examine and collate literature on the nature of occupational therapy intervention in this field, to increase ...
• Targeting immune cell metabolism in the treatment of inflammatory bowel disease 

  Bittencourt, Vanessa Zaiatz; Jones, Fiona; Doherty, Glen; Ryan, Elizabeth J. (Oxford University Press, 2021)

  The cells of the immune system are highly dynamic, constantly sensing and adapting to changes in their surroundings. Complex metabolic path-ways govern leukocytes’ ability to fine-tune their responses to external threats. ...
• An initial evaluation of the safety of a disposable oscillating positive expiratory pressure device in patients with chronic obstructive pulmonary disease: a short-term pilot study 

  O'Sullivan, Kevin Jeremiah; Power, Valerie; Linnane, Barry; McGrath, Deirdre; Fogarty, Hilda; Ryan, Martina; White, Rebecca; Noonan, Conor; Mulloy, Eithne; O'Sullivan, Leonard; Dunne, Colum P. (BMC, 2021)

  Background: Handheld oscillating positive expiratory pressure (OPEP) devices have been a mainstay of treatment for patients with hypersecretory conditions such as cystic fibrosis (CF) and chronic obstructive pulmonary ...
• Students’ use of caffeine, alcohol, dietary supplements, and illegal substances for improving academic performance in a New Zealand university 

  Narayanan, Anantha; Gill, Malcolm; Leem, Chaey; Li, Cassandra; Smith, Frances Mein; Shepherd, Ben; Ting, Selene; van Bart, Karin; Green, James J.; Samaranayaka, Ari; Ergler, Christina; Macmillan, Alexandra (Taylor & Francis, 2021)

  This study aimed to describe patterns of use and attitudes towards a broad variety of substances for improving academic performance at a New Zealand university. 685 students (from 1800 invited) completed an online questionnaire ...
• ‘Doctors can’t be doctors all of the time’: a qualitative study of how general practitioners and medical students negotiate public-professional and private-personal realms using social media 

  Marshal, Megan; Niranjan, Vikram; Spain, Eimear; MacDonagh, Joe; O'Doherty, Jane; O'Connor, Raymond; O'Regan, Andrew (BMJ, 2021)

  Objective The objective of this study is to explore the experiences and perspectives of general practitioners’ and medical students’ use of, and behaviour on, social media and to understand how they negotiate threats ...
• Effectiveness of acute geriatric unit care on functional decline and process outcomes among older adults admitted to hospital with acute medical complaints: a protocol for a systematic review 

  O'Shaughnessy, Íde; Robinson, Katie; O'Connor, Margaret; Conneely, Mairéad; Ryan, Damien; Steed, Fiona; Carey, Leonora; Leahy, Aoife; Galvin, Rose (BMJ, 2021)

  Introduction Older adults are clinically heterogeneous and are at increased risk of adverse outcomes during hospitalisation due to the presence of multiple comorbid conditions and reduced homoeostatic reserves. Acute ...
• The role of an anti-inflammatory diet in conjunction to COVID-19 

  Ling, Victoria; Zabetakis, Ioannis (MDPI, 2021)

  Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), otherwise known as COVID-19, has challenged healthcare systems at an international level. COVID-19 suppresses the immune system by causing a systemic inflammatory ...
• High sitting time is a behavioral risk factor for blunted improvement in depression across 8 weeks of the COVID-19 pandemic in April–May 2020 

  Meyer, Jacob D.; O'Connor, John; McDowell, Cillian P.; Lansing, Jeni E.; Brower, Cassandra S.; Herring, Matthew P. (Frontiers Media, 2021)

  The COVID-19 pandemic has elicited increased sedentary behaviors, decreased moderate-to-vigorous physical activity (MVPA), and worsened mental health, yet the longitudinal impact of these changes and their inter-relations ...

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