• Temporal trends in acute kidney injury across health care settings in the Irish health system: a cohort study 

  Stack, Austin G.; Li, Xia; Kaballo, Mohamed; Elsayed, Mohamed E.; Johnson, Howard; Murray, Patrick T.; Saran, Rajiv; Browne, Leonard D. (Oxford University Press, 2018)

  Background. Complete ascertainment of the true rates of acute kidney injury (AKI) and emerging trends are essential for planning of preventive strategies within health systems. Methods. We conducted a retrospective ...
• ATP synthase F1 subunits recruited to centromeres by CENP-A are required for male meiosis 

  Collins, Catríona M.; Malacrida, Beatrice; Burke, Colin; Kiely, Patrick A.; Dunleavy, Elaine M. (Nature Publishing Group, 2018)

  The histone H3 variant CENP-A epigenetically defines the centromere and is critical for chromosome segregation. Here we report an interaction between CENP-A and subunits of the mitochondrial ATP synthase complex in the ...
• Novel smart inspection-class ROV for use in challenging conditions 

  Capocci, Romano (University of Limerick, 2018)

  In this thesis, a novel smart inspection-ROV is described. The research addresses the need for a highly-capable ROV with abilities to carry out close-quarters inspections of marine renewable energy installations in their ...
• A new approach to customer value improvement through co-leadership, trust and methodology for increased organisational return on investment 

  Heavey, Colm (University of Limerick, 2013)

  In an era where economic turbulence is constant with many organisations rightsizing to remain competitive, customer value improvement (CVI) is central to organisational strategy. As a panacea for this customer value ...
• Analysis of direct interconnection technique for offshore airborne wind energy systems under normal and fault conditions 

  Salari, Mahdi Ebrahimi; Coleman, Joseph; Toal, Daniel (Elsevier, 2019)

  Direct interconnection is a novel technique for interconnecting offshore airborne wind energy (AWE) generators which facilitates the removal of power converters from the offshore generation site. In this technique, unlike ...
• Age and sex related differences in shoulder abduction fatigue 

  Collins, John D.; O'Sullivan, Leonard (BioMed Central, 2018)

  Background: Injury prevalence data commonly indicate trends of higher rates of work-related musculoskeletal disorders in older workers over their younger counterparts, and for females more than males. The purpose of ...
• The use of single armed observational data to closing the gap in otherwise disconnected evidence networks: a network meta-analysis in multiple myeloma 

  Schmitz, Susanne; Maguire, Áine; Morris, James; Ruggeri, Kai; Haller, Elisa; Kuhn, Isla; Leahy, Joy; Homer, Natalia; Khan, Ayesha; Bowden, Jack; Buchanan, Vanessa; O'Dwyer, Michael; Cook, Gordon; Walsh, Cathal Dominic (BioMed Central, 2018)

  Background: Network meta-analysis (NMA) allows for the estimation of comparative effectiveness of treatments that have not been studied in head-to-head trials; however, relative treatment effects for all interventions can ...
• Prospects of zinc supplementation in autism spectrum disorders and shankopathies Such as Phelan McDermid Syndrome. 

  Hagmeyer, Simone; Sauer, Ann Katrin; Grabrucker, Andreas M. (Frontiers Media, 2018)

  The loss of one copy of SHANK3 (SH3 and multiple ankyrin repeat domains 3) in humans highly contributes to Phelan McDermid syndrome (PMDS). In addition, SHANK3 was identified as a major autism candidate gene. Interestingly, ...
• Underwater manipulators: a review 

  Sivčev, Satja; Coleman, Joseph; Omerdić, Edin; Dooly, Gerard; Toal, Daniel (Elsevier, 2018)

  This paper describes the state-of-the art in the area of underwater robot manipulator systems. A brief introduction is given on the use of manipulators in various offshore industries for different subsea intervention a ...
• Reduced plaque size and inflammation in the APP23 mouse model for Alzheimer’s disease after chronic application of polymeric nanoparticles for CNS targeted zinc delivery 

  Vilella, Antonietta; Belletti, Daniela; Sauer, Ann Katrin; Hagmeyer, Simone; Sarowar, Tasnuva; Masoni, Martina; Stasiak, Natalia; Mulvihill, John J.; Ruozi, Barbara; Forni, Flavio; Vandelli, Maria Angela; Tosi, Giovanni; Zoli, Michele; Grabrucker, Andreas M. (Elsevier, 2017)

  A local dyshomeostasis of zinc ions in the vicinity of amyloid aggregates has been proposed in Alzheimer’s disease (AD) due to the sequestration of zinc in senile plaques. While an increase in zinc levels may promote the ...
• Physical activity and sleep problems in 38 low- and middle-income countries 

  Vancampfort, Davy; Stubbs, Brendon; Smith, Lee; Hallgren, Mats; Firth, Joseph; Herring, Matthew P.; Probst, Michel; Koyanagi, Ai (Elsevier, 2018)

  Objective: Although physical activity (PA) is associated with a reduction of a wide range of sleep problems, it remains uncertain whether complying with the international guidelines of 150 min of moderate to vigorous PA ...
• Temporal trends in hyperuricaemia in the Irish health system from 2006-2014: a cohort study 

  Kumar A. U., Arun; Browne, Leonard D.; Li, Xia; Adeeb, Fahd; Perez-Ruiz, Fernando; Fraser, Alexander D.; Stack, Austin G. (Public Library of Science, 2018)

  Background Elevated serum uric acid (sUA) concentrations are common in the general population and are associated with chronic metabolic conditions and adverse clinical outcomes. We evaluated secular trends in the burden ...
• Clinical evaluation of a safety-device to prevent urinary catheter inflation related injuries 

  Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Forde, James C.; Walsh, Michael T. (Elsevier, 2018)

  OBJECTIVE: To evaluate the feasibility of a novel “safety-valve” device for preventing catheter related urethral trauma during urethral catheterization (UC). To assess the opinions of clinicians on the performance of the ...
• Longitudinal relations of mental health and motivation among elite student-athletes across a condensed season: plausible influence of academic and athletic schedule 

  Sheehan, Rachel B.; Herring, Matthew P.; Campbell, Mark J. (Elsevier, 2018)

  Objectives: This study characterised mental health, motivation, and their interrelations among 38 elite studentathletes over a 13-week season, while monitoring and considering the influence of their athletic and ...
• Hybrid nanoparticles as a new technological approach to enhance the delivery of cholesterol into the brain 

  Belletti, Daniela; Grabrucker, Andreas M.; Pederzoli, Francesca; Menrath, Isabel; Vandelli, Maria Angela; Tosi, Giovanni; Duskey, Thomas Jason; Forni, Flavio; Ruozi, Barbara (Elsevier, 2018)

  Restoration of the Chol homeostasis in the Central Nervous System (CNS) could be beneficial for the treatment of Huntington's Disease (HD), a progressive, fatal, adult-onset, neurodegenerative disorder. Unfortunately, Chol ...
• A multi-agent systems approach for sustainable supplier selection and order allocation in a partnership supply chain 

  Ghadimi, Pezhman; Ghassemi Toosi, Farshad; Heavey, Cathal (Elsevier, 2018)

  Recently, incorporating sustainability into the buyer-supplier sourcing decisions has achieved a considerable amount of attentions among researchers and industrial enterprises who are attempting to move towards sustainable ...
• Characterisation of human urethral rupture thresholds for urinary catheter inflation related injuries 

  Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Hess, J.; Walsh, Michael T. (Elsevier, 2018)

  Data on urethral catheter related injuries is sparse. In this study we aimed to characterise urethral diametric strain and urinary catheter inflation pressure thresholds that precede human urethral trauma during urethral ...
• Assessment of an active industrial exoskeleton to aid dynamic lifting and lowering manual handling tasks 

  Huysamen, Kirsten; de Looze, Michiel P.; Bosch, Tim; Ortiz, Jesús; Toxiri, Stefano; O'Sullivan, Leonard (Elsevier, 2018)

  The aim of this study was to evaluate the effect of an industrial exoskeleton on muscle activity, perceived musculoskeletal effort, measured and perceived contact pressure at the trunk, thighs and shoulders, and subjective ...
• Prevalence and correlates of central venous catheter use among haemodialysis patients in the Irish health system - a national study 

  Hussein, Wael F.; Mohammed, Husham; Browne, Leonard D.; Plant, Liam; Stack, Austin G. (BioMed Central, 2018)

  Background: Central venous catheters (CVC) are associated with substantial morbidity and mortality among patients undergoing haemodialysis (HD), yet they are frequently used as the primary vascular access for many patients ...
• Fully automatic visual servoing control for work-class marine intervention ROVs 

  Sivčev, Satja; Rossi, Matija; Coleman, Joseph; Dooly, Gerard; Omerdić, Edin; Toal, Daniel (Elsevier, 2018)

  ROVs with hydraulic manipulators are extensively used for subsea intervention. With camera feedback from the scene, manipulators are teleoperated and slaved to pilot held master arms. While standard for offshore oil and ...

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