• Tuning the biomimetic behavior of hybrid scaffolds for bone tissue engineering through surface modifications and drug immobilization 

  Ghorbani, Farnaz; Ghalandari, Behafarid; Sahranavard, Melika; Zamanian, Ali; Collins, Maurice N. (Elsevier, 2021)

  Bone defects arising from injury and/or disease are a common and debilitating clinical lesion. While the development of tissue microenvironments utilizing biomimetic constructs is an emerging approach for bone tissue ...
• The influence of maximal strength and knee angle on the reliability of peak force in the isometric squat 

  Lynch, Arthur; Davies, Robert W.; Jakeman, Philip M.; Locke, Tim; Allardyce, Joanna M.; Carson, Brian P. (MDPI, 2021)

  This study aimed to investigate the test-retest reliability of peak force in the isometric squat across the strength spectrum using coefficient of variation (CV) and intra-class correlation coefficient (ICC). On two separate ...
• Calcium-dependent signalling in B-cell lymphomas 

  Berditchevski, Fedor; Fennell, Eanna; Murray, Paul G. (Springer Nature, 2021)

  Induced waves of calcium fluxes initiate multiple signalling pathways that play an important role in the differentiation and maturation of B-cells. Finely tuned transient Ca+2 fluxes from the endoplasmic reticulum in ...
• Epstein–Barr virus reactivation influences clonal evolution in human herpesvirus-8-related lymphoproliferative disorders 

  Granai, Massimo; Facchetti, Mattia; Mancini, Virginia; Goedhals, Jacqueline; Sherriff, Alicia; Mundo, Lucia; Bellan, Cristiana; Amato, Teresa; Sorrentino, Ester; Ungari, Marco; Raphael, Martine; Leoncini, Lorenzo; Facchetti, Fabio; Lazzi, Stefano (Wiley and Sons Ltd, 2021)

  Background: Human herpesvirus-8 (HHV8) is a lymphotropic virus associated with different lymphoproliferative disorders, including primary effusion lymphoma (PEL), multicentric Castleman’s disease (MCD), diffuse large ...
• Resisted sled sprint kinematics: The acute effect of load and sporting population 

  Osterwald, Katja M.; Kelly, David T.; Comyns, Thomas M.; Ciarán, Ó Catháin (MDPI, 2021)

  In this study, we assessed the acute kinematic effects of different sled load conditions (unloaded and at 10%, 20%, 30% decrement from maximum velocity (Vdec)) in different sporting populations. It is well-known that an ...
• Exercise and the prevention of frailty – evidence from a community-based medical exercise intervention 

  Lewis, M.; Kelly, S.; Woods, Catherine B.; O'Connor, R. (Springer, 2021)

  We were interested to read the paper by ‘Moloney et al on Frailty, COVID-19 Disease Severity and Outcome Among Hospitalised Older Adults’, in which frail patients were more likely to be admitted despite having mild Covid. ...
• Effectiveness of interventions to prevent falls for people with multiple sclerosis, parkinson’s disease and stroke: an umbrella review 

  O'Malley, Nicola; Clifford, Amanda M.; Conneely, Mairéad; Casey, Bláthín; Coote, Susan (BMC, 2021)

  Background: The implementation of condition-specific falls prevention interventions is proving challenging due to lack of critical mass and resources. Given the similarities in falls risk factors across stroke, Parkinson’s ...
• Serological markers of SARS-CoV-2 infection; anti-nucleocapsid antibody positivity may not be the ideal marker of natural infection in vaccinated individuals 

  Allen, Niamh; Brady, Melissa; Carrion Martin, Antonio Isidro; Domegan, Lisa; Walsh, Cathal Dominic; Doherty, Lorraine; Ni Riain, Una; Bergin, Colm; Fleming, Catherine; Conlon, Niall (Elsevier, 2021)

  Dear Editor, We write in response to correspondence from Whitaker et al. in this Journal (1). The authors demonstrate increases in seropositivity for SARS-CoV-2 antibodies against the spike protein as the roll out of ...
• Measurement and prevalence of adult physical activity levels in Arab countries 

  Murtagh, Elaine M.; Shalash, A.; Martin, R.; Rmeileh, N. Abu (Elsevier, 2021)

  Objectives: This study aims to examine the reported prevalence of sufficient physical activity among adults in Arab countries and to determine the use of validated instruments for assessing physical activity. Study design: ...
• Collective conceptualization of parental support of dual career athletes: The EMPATIA framework 

  Varga, Kinga; MacDonncha, Ciaran; Blondel, Laurence; Bozzano, Enrico; Burlot, Fabrice; Costa, Rute; Debois, Nadine; Delon, Dominique; Figueiredo, Antonio; Foerster, Joerg; Gjaka, Masar; Goncalves, Carlos; Guidotti, Flavia; Pesce, Caterina; Pisl, Andrej; Rheinisch, Eoin; Rolo, Ana; Rozman, Sara; Ryan, Gary; Templet, Anne; Tessitore, Antonio; Warrington, Giles; Capranica, Laura; Doupona, Mojca (Public Library of Science, 2021)

  This study aimed to use a concept mapping methodology to develop a European framework of the needs of parents/guardians (P/G) for supporting athletes combining sport and education (dual career, DC By means of a concept ...
• Solidarity matters: prototypicality and minority and majority adherence to national COVID-19 health advice 

  Foran, Aoife-Marie; Roth, Jenny; Jay, Sarah; Griffin, Siobhan M.; Maher, Paul J.; McHugh, Cillian; Bradshaw, Daragh; Ryan, Megan; Quayle, Michael; Muldoon, Orla T. (Ubiquity Press, 2021)

  The effectiveness of measures introduced to minimise the spread of Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS-CoV-2 or COVID-19) depends on compliance from all members of society. The Irish response to COVID-19 ...
• Ghost-UNet: an asymmetric encoder-decoder architecture for semantic segmentation From scratch 

  Kazerouni, Iman Abaspur; Dooly, Gerard; Toal, Daniel (IEEE Computer Society, 2021)

  One of the most important key points in the intelligent transportation systems is scene understanding of the known and unknown surrounding environment to achieve a safe driving for smart mobile robots and cars. Semantic ...
• Burkitt lymphoma with a granulomatous reaction: an M1/Th1-polarised microenvironment is associated with controlled growth and spontaneous regression 

  Granai, Massimo; Lazzi, Stefano; Mancini, Virginia; Akarca, Ayse; Santi, Raffaella; Vergoni, Federica; Sorrentino, Ester; Guazzo, Raffaella; Mundo, Lucia; Cevenini, Gabriele; Tripodo, Claudio; Di Stefano, Gioia; Puccini, Benedetta; Ponzoni, Maurilio; Sabattini, Elena; Agostinelli, Claudio; Bassullu, Nuray; Tecimer, Tulay; Demiroz, Ahu Senem; Mnango, Leah; Dirnhofer, Stephan; Quintanilla-Martinez, Leticia; Marafioti, Teresa; Fend, Falko; Leoncini, Lorenzo (Wiley and Sons Ltd, 2021)

  Aims Burkitt lymphoma (BL) is an aggressive B-cell lymphoma that, in some instances, may show a granulomatous reaction associated with a favourable prognosis and occasional spontaneous regression. In the present study, ...
• A feedback journey: employing a constructivist approach to the development of feedback literacy among health professional learners 

  O'Connor, Anne; McCurtin, Arlene (BMC, 2021)

  Background: Feedback, if effectively provided by the teacher and utilised by the learner, enables improvement in academic performance. It is clear from current literature that the provision of feedback by teachers is not ...
• Microalgal lipid extracts have potential to modulate the inflammatory response: A critical review 

  Conde, Tiago Alexandre; Zabetakis, Ioannis; Tsoupras, Alexandros; Medina, Isabel; Costa, Margarida; Silva, Joana; Neves, Bruno; Domingues, Pedro; Domingues, M. Rosário (MDPI, 2021)

  Noncommunicable diseases (NCD) and age-associated diseases (AAD) are some of the gravest health concerns worldwide, accounting for up to 70% of total deaths globally. NCD and AAD, such as diabetes, obesity, cardiovascular ...
• "SingStrong": Singing for better lung health in COPD - A pilot study. 

  Cahalan, Róisin Máire; Green, James A.; Meade, Ciara; Griffin, Anne (Taylor and Francis, 2021)

  Background: Chronic Obstructive Pulmonary Disease (COPD) affects up to 440,000 people in Ireland. Multiple domains of biopsychosocial health are affected. Community-based interventions supporting behavioral change and ...
• LRG1 expression is elevated in the eyes of patients with neovascular age-related macular degeneration 

  Mundo, Lucia; Tosi, Gian Marco; Lazzi, Stefano; Pertile, Grazia; Parolini, Barbara; Neri, Giovanni; Posarelli, Matteo; De Benedetto, Elena; Bacci, Tommaso; Silvestri, Ennio; Siciliano, Maria Chiara; Barbera, Stefano; Orlandini, Maurizio; Greenwood, John; Moss, Stephen E.; Galvagni, Federico (MDPI, 2021)

  Leucine-rich a-2-glycoprotein 1 (LRG1) is a candidate therapeutic target for treating the neovascular form of age-related macular degeneration (nvAMD). In this study we examined the expression of LRG1 in eyes of nvAMD ...
• Epidemiology of shoulder injuries in schoolboy rugby union in Ireland 

  Leahy, Therese M.; Kenny, Ian C.; Campbell, Mark J.; Warrington, Giles D.; Cahalan, Róisin Máire; Harrison, Andrew J.; Lyons, Mark; Glynn, Liam G.; O'Sullivan, Kieran; Purtill, Helen; Comyns, Thomas M. (SAGE, 2021)

  Background: The shoulder has been reported as a frequent location of injury in adult professional and amateur rugby, with match injury incidence rates ranging from 1.8 to 3 per 1000 player-hours (h). An increased understanding ...
• Quality in the time of chaos: reflections from teaching, learning and practice 

  Kearns, Áine; Gallagher, Aoife L.; Cronin, Jena (American Speech-Language-Hearing Association, 2021)

  Purpose The global pandemic has significantly disrupted clinical practice and health professional education. In this commentary article, we describe our experiences from the perspectives of a student, a practice educator, ...
• Mechanically stimulated osteocytes promote the proliferation and migration of breast cancer cells via a potential CXCL1/2 mechanism 

  Dwivedi, Anushree; Kiely, Patrick A.; Hoey, David A. (Elsevier, 2021)

  Bone represents the most common site for breast cancer metastasis. Bone is a highly dynamic organ that is constantly adapting to its biophysical environment, orchestrated largely by the resident osteocyte network. Osteocytes ...

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