• Prospects of zinc supplementation in autism spectrum disorders and shankopathies Such as Phelan McDermid Syndrome. 

  Hagmeyer, Simone; Sauer, Ann Katrin; Grabrucker, Andreas M. (Frontiers Media, 2018)

  The loss of one copy of SHANK3 (SH3 and multiple ankyrin repeat domains 3) in humans highly contributes to Phelan McDermid syndrome (PMDS). In addition, SHANK3 was identified as a major autism candidate gene. Interestingly, ...
• Underwater manipulators: a review 

  Sivčev, Satja; Coleman, Joseph; Omerdić, Edin; Dooly, Gerard; Toal, Daniel (Elsevier, 2018)

  This paper describes the state-of-the art in the area of underwater robot manipulator systems. A brief introduction is given on the use of manipulators in various offshore industries for different subsea intervention a ...
• Reduced plaque size and inflammation in the APP23 mouse model for Alzheimer’s disease after chronic application of polymeric nanoparticles for CNS targeted zinc delivery 

  Vilella, Antonietta; Belletti, Daniela; Sauer, Ann Katrin; Hagmeyer, Simone; Sarowar, Tasnuva; Masoni, Martina; Stasiak, Natalia; Mulvihill, John J.E; Ruozi, Barbara; Forni, Flavio; Vandelli, Maria Angela; Tosi, Giovanni; Zoli, Michele; Grabrucker, Andreas M. (Elsevier, 2017)

  A local dyshomeostasis of zinc ions in the vicinity of amyloid aggregates has been proposed in Alzheimer’s disease (AD) due to the sequestration of zinc in senile plaques. While an increase in zinc levels may promote the ...
• Physical activity and sleep problems in 38 low- and middle-income countries 

  Vancampfort, Davy; Stubbs, Brendon; Smith, Lee; Hallgren, Mats; Firth, Joseph; Herring, Matthew P.; Probst, Michel; Koyanagi, Ai (Elsevier, 2018)

  Objective: Although physical activity (PA) is associated with a reduction of a wide range of sleep problems, it remains uncertain whether complying with the international guidelines of 150 min of moderate to vigorous PA ...
• Temporal trends in hyperuricaemia in the Irish health system from 2006-2014: a cohort study 

  Kumar A. U., Arun; Browne, Leonard D.; Li, Xia; Adeeb, Fahd; Perez-Ruiz, Fernando; Fraser, Alexander D.; Stack, Austin G. (Public Library of Science, 2018)

  Background Elevated serum uric acid (sUA) concentrations are common in the general population and are associated with chronic metabolic conditions and adverse clinical outcomes. We evaluated secular trends in the burden ...
• Clinical evaluation of a safety-device to prevent urinary catheter inflation related injuries 

  Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Forde, James C.; Walsh, Michael T. (Elsevier, 2018)

  OBJECTIVE: To evaluate the feasibility of a novel “safety-valve” device for preventing catheter related urethral trauma during urethral catheterization (UC). To assess the opinions of clinicians on the performance of the ...
• Longitudinal relations of mental health and motivation among elite student-athletes across a condensed season: plausible influence of academic and athletic schedule 

  Sheehan, Rachel B.; Herring, Matthew P.; Campbell, Mark J. (Elsevier, 2018)

  Objectives: This study characterised mental health, motivation, and their interrelations among 38 elite studentathletes over a 13-week season, while monitoring and considering the influence of their athletic and ...
• Hybrid nanoparticles as a new technological approach to enhance the delivery of cholesterol into the brain 

  Belletti, Daniela; Grabrucker, Andreas M.; Pederzoli, Francesca; Menrath, Isabel; Vandelli, Maria Angela; Tosi, Giovanni; Duskey, Thomas Jason; Forni, Flavio; Ruozi, Barbara (Elsevier, 2018)

  Restoration of the Chol homeostasis in the Central Nervous System (CNS) could be beneficial for the treatment of Huntington's Disease (HD), a progressive, fatal, adult-onset, neurodegenerative disorder. Unfortunately, Chol ...
• A multi-agent systems approach for sustainable supplier selection and order allocation in a partnership supply chain 

  Ghadimi, Pezhman; Ghassemi Toosi, Farshad; Heavey, Cathal (Elsevier, 2018)

  Recently, incorporating sustainability into the buyer-supplier sourcing decisions has achieved a considerable amount of attentions among researchers and industrial enterprises who are attempting to move towards sustainable ...
• Characterisation of human urethral rupture thresholds for urinary catheter inflation related injuries 

  Davis, Niall Francis; Cunnane, Eoghan M.; Mooney, Rory; Hess, J.; Walsh, Michael T. (Elsevier, 2018)

  Data on urethral catheter related injuries is sparse. In this study we aimed to characterise urethral diametric strain and urinary catheter inflation pressure thresholds that precede human urethral trauma during urethral ...
• Assessment of an active industrial exoskeleton to aid dynamic lifting and lowering manual handling tasks 

  Huysamen, Kirsten; de Looze, Michiel P.; Bosch, Tim; Ortiz, Jesús; Toxiri, Stefano; O'Sullivan, Leonard (Elsevier, 2018)

  The aim of this study was to evaluate the effect of an industrial exoskeleton on muscle activity, perceived musculoskeletal effort, measured and perceived contact pressure at the trunk, thighs and shoulders, and subjective ...
• Prevalence and correlates of central venous catheter use among haemodialysis patients in the Irish health system - a national study 

  Hussein, Wael F.; Mohammed, Husham; Browne, Leonard D.; Plant, Liam; Stack, Austin G. (BioMed Central, 2018)

  Background: Central venous catheters (CVC) are associated with substantial morbidity and mortality among patients undergoing haemodialysis (HD), yet they are frequently used as the primary vascular access for many patients ...
• Inspection-Class remotely operated vehicles—a review 

  Capocci, Romano; Dooly, Gerard; Omerdić, Edin; Coleman, Joseph; Newe, Thomas; Toal, Daniel (MDPI, 2018)

  This paper presents a review of inspection-class Remotely Operated Vehicles (ROVs). The review divides the classification of inspection-class ROVs; categorising the vehicles in order of size and capability. A state of the ...
• Fully automatic visual servoing control for work-class marine intervention ROVs 

  Sivčev, Satja; Rossi, Matija; Coleman, Joseph; Dooly, Gerard; Omerdić, Edin; Toal, Daniel (Elsevier, 2018)

  ROVs with hydraulic manipulators are extensively used for subsea intervention. With camera feedback from the scene, manipulators are teleoperated and slaved to pilot held master arms. While standard for offshore oil and ...
• Evaluating personality as a moderator of the association between life events stress and cardiovascular reactivity to acute stress 

  Gallagher, Stephen; O'Riordan, Adam; McMahon, Grace; Creaven, Ann-Marie (Elsevier, 2018)

  The present study investigated the possible interaction between life events stress and personality in predicting cardiovascular stress responses. Participants (N = 184) completed psychometric measures of life event stress ...
• Is matrix gla protein associated with vascular calcification? a systematic review 

  Barrett, Hilary; O'Keeffe, Mary; Kavanagh, Eamon; Walsh, Michael T.; O'Connor, Eilbhlís M. (MDPI, 2018)

  Specific patient cohorts are at increased risk of vascular calcification. Functional matrix-gla protein (MGP), a tissue-derived vitamin K dependent protein, is reported to be an important inhibitor of vascular calcification ...
• Prevalence of potentially inappropriate prescribing in a subpopulation of older European clinical trial participants: a cross-sectional study 

  O'Riordan, David; Elodie Aubert, Carole; Walsh, Kieran A.; Van Dorland, Anette; Rodondi, Nicolas; Du Puy, Robert S.; Poortvliet, Rosalinde K E.; Gussekloo, Jacobijn; Sinnott, Carol; Byrne, Stephen; Galvin, Rose; Jukema, J Wouter; Mooijaart, Simon P.; Baumgartner, Christine; McCarthy, Vera; Walsh, Elaine K.; Collet, Tinh-Hai; Dekkers, Olaf M.; Blum, Manuel R.; Kearney, Patricia M. (BMJ Publishing Group, 2018)

  Objectives To estimate and compare the prevalence and type of potentially inappropriate prescribing (PIP) and potential prescribing omissions (PPOs) among communitydwelling older adults (≥65 years) enrolled to a clinical ...
• Identifying trial recruitment uncertainties using a James Lind alliance priority setting partnership – the priority (prioritising recruitment in randomised trials) study 

  Healy, Patricia; Galvin, Sandra; Williamson, Paula R.; Treweek, Shaun; Whiting, Caroline; Maeso, Beccy; Bray, Christopher; Brocklehurst, Peter; Clarke-Moloney, Mary; Douiri, Abdel; Gamble, Carrol; Gardner, Heidi R.; Mitchell, Derick; Stewart, Derek; Jordan, Joan; O'Donnell, Martin; Clarke, Mike; Pavitt, Sue H.; Woodford Guegan, Eleanor; Blatch-Jones, Amanda; Smith, Valerie; Reay, Hannah; Devane, Declan (BioMed Central, 2018)

  Background: Despite the problem of inadequate recruitment to randomised trials, there is little evidence to guide researchers on decisions about how people are effectively recruited to take part in trials. The PRioRiTy ...
• High-Sensitivity cardiac troponin I and the diagnosis of coronary artery disease in patients with suspected angina pectoris 

  Adamson, Philip D.; Hunter, Amanda; Madsen, Debbie M.; Shah, Anoop S.V.; McAllister, David A.; Pawade, Tania A.; Williams, Michelle C.; Berry, Colin; Boon, Nicholas A.; Flather, Marcus; Forbes, John F.; McLean, Scott; Roditi, Giles; Timmis, Adam D.; van Beek, Edwin J.R.; Dweck, Marc R.; Mickley, Hans; Mills, Nicholas L.; Newby, David E. (American Heart Association, 2018)

  Background: We determined whether high-sensitivity cardiac troponin I can improve the estimation of the pretest probability for obstructive coronary artery disease (CAD) in patients with suspected stable angina. Methods ...
• What Is the impact of physical activity and physical function on the development of multimorbidity in older adults over time? A population-based cohort study 

  Ryan, Aine; Murphy, Catriona; Boland, Fiona; Galvin, Rose; Smith, Susan M. (Oxford University Press on behalf of The Gerontological Society of America, 2018)

  Background: Multimorbidity is recognized internationally as having a serious impact on health outcomes. It is associated with reduced quality of life, increased health care utilization, and future functional decline. ...

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