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Multilayered polyelectrolyte microcapsules: interaction with the enzyme cytochrome C oxidase

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Show simple item record Pastorino, Laura Dellacasa, Elena Noor, Mohamed R. Soulimane, Tewfik Bianchini, Paolo D’Autilia, Francesca Antipov, Alexei Diaspro, Alberto Tofail, Syed A.M. Ruggiero, Carmelina 2015-06-22T10:42:19Z 2015-06-22T10:42:19Z 2014
dc.description peer-reviewed en_US
dc.description.abstract Cell-sized polyelectrolyte capsules functionalized with a redox-driven proton pump protein were assembled for the first time. The interaction of polyelectrolyte microcapsules, fabricated by electrostatic layer-by-layer assembly, with cytochrome c oxidase molecules was investigated. We found that the cytochrome c oxidase retained its functionality, that the functionalized microcapsules interacting with cytochrome c oxidase were permeable and that the permeability characteristics of the microcapsule shell depend on the shell components. This work provides a significant input towards the fabrication of an integrated device made of biological components and based on specific biomolecular functions and properties. en_US
dc.language.iso eng en_US
dc.publisher Public Library of Science en_US
dc.relation 280804 en_US
dc.relation.ispartofseries PLoS ONE;9, 11, e112912
dc.subject polyelectrolyte capsules en_US
dc.subject biological components en_US
dc.title Multilayered polyelectrolyte microcapsules: interaction with the enzyme cytochrome C oxidase en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.identifier.doi 10.1371/journal.pone.0112192
dc.contributor.sponsor ERC en_US
dc.relation.projectid 280804 en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1575673

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