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Validity of synthetic bone as a substitute for osteoporotic cadaveric femoral heads in mechanical testing: a biomechanical study

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dc.contributor.author O'Neill, F.
dc.contributor.author Condon, F.
dc.contributor.author McGloughlin, Timothy M.
dc.contributor.author Lenehan, Brian
dc.contributor.author Coffey, Calvin J.
dc.contributor.author Walsh, Michael T.
dc.date.accessioned 2015-04-10T16:36:28Z
dc.date.available 2015-04-10T16:36:28Z
dc.date.issued 2012
dc.identifier.citation O'Neill, F,Condon, F,McGloughlin, T,Lenehan, B,Coffey, C,Walsh, M (2012) 'Validity of synthetic bone as a substitute for osteoporotic cadaveric femoral heads in mechanical testing A BIOMECHANICAL STUDY'. Bone & Joint Research, 1 :50-55. en_US
dc.identifier.uri http://hdl.handle.net/10344/4410
dc.description peer-reviewed en_US
dc.description.abstract IntroductionThe objective of this study was to determine if a synthetic bone substitute would provide results similar to bone from osteoporotic femoral heads during in vitro testing with orthopaedic implants. If the synthetic material could produce results similar to those of the osteoporotic bone, it could reduce or eliminate the need for testing of implants on bone.MethodsPushout studies were performed with the dynamic hip screw (DHS) and the DHS Blade in both cadaveric femoral heads and artificial bone substitutes in the form of polyurethane foam blocks of different density. The pushout studies were performed as a means of comparing the force displacement curves produced by each implant within each material.ResultsThe results demonstrated that test material with a density of 0.16 g/cm(3) (block A) produced qualitatively similar force displacement curves for the DHS and qualitatively and quantitatively similar force displacement curves for the DHS Blade, whereas the test material with a density of 0.08 g/cm(3) (block B) did not produce results that were predictive of those recorded within the osteoporotic cadaveric femoral heads.ConclusionThis study demonstrates that synthetic material with a density of 0.16 g/cm(3) can provide a good substitute for cadaveric osteoporotic femoral heads in the testing of implants. However we do recognise that no synthetic material can be considered as a definitive substitute for bone, therefore studies performed with artificial bone substrates may need to be validated by further testing with a small bone sample in order to produce conclusive results. en_US
dc.language.iso eng en_US
dc.publisher British Editorial Society of Bone and Joint Surgery en_US
dc.relation.ispartofseries Bone and Joint Research;1 (4), pp. 50-55
dc.relation.uri http://www.bjr.boneandjoint.org.uk/content/1/4/50
dc.subject intertrochanteric fracture en_US
dc.subject biomechanical study en_US
dc.subject artificial bone substitute en_US
dc.subject DHS en_US
dc.subject DHS blade en_US
dc.subject osteoporotic bone en_US
dc.title Validity of synthetic bone as a substitute for osteoporotic cadaveric femoral heads in mechanical testing: a biomechanical study en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.date.updated 2015-04-10T16:22:09Z
dc.description.version PUBLISHED
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1575893
dc.internal.copyrightchecked Yes
dc.description.status peer-reviewed


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