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Role of far infra-red therapy in dialysis arterio-venous fistula maturation and survival: systematic review and meta-analysis

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dc.contributor.author Bashar, Khalid
dc.contributor.author Healy, Donagh A.
dc.contributor.author Kheirelseid, Elrasheid A. H.
dc.contributor.author Walsh, Michael T.
dc.contributor.author Clarke-Moloney, Mary
dc.contributor.author Burke, Paul E.
dc.contributor.author Kavanagh, Eamon G.
dc.contributor.author Walsh, Stewart R.
dc.date.accessioned 2014-12-04T18:14:22Z
dc.date.available 2014-12-04T18:14:22Z
dc.date.issued 2014
dc.identifier.citation Fistula Maturation and Survival: Systematic Review and Meta-Analysis'. Plos One, 9 . en_US
dc.identifier.uri http://hdl.handle.net/10344/4200
dc.description peer-reviewed en_US
dc.description.abstract Introduction: A well-functioning arteriovenous fistula (AVF) is the best modality for vascular access in patients with end-stage renal disease (ESRD) requiring haemodialysis (HD). However, AVFs' main disadvantage is the high rate of maturation failure, with approximately one third (20%-50%) not maturing into useful access. This review examine the use of Far-Infra Red therapy in an attempt to enhance both primary (unassisted) and secondary (assisted) patency rates for AVF in dialysis and pre-dialysis patients.Method: We performed an online search for observational studies and randomised controlled trials (RCTs) that evaluated FIR in patients with AVF. Eligible studies compared FIR with control treatment and reported at least one outcome measure relating to access survival. Primary patency and secondary patency rates were the main outcomes of interest.Results: Four RCTs (666 patients) were included. Unassisted patency assessed in 610 patients, and was significantly better among those who received FIR (228/311) compared to (185/299) controls (pooled risk ratio of 1.23 [1.12-1.35], p = 0.00001). In addition, the two studies which reported secondary patency rates showed significant difference in favour of FIR therapy-160/168 patients - compared to 140/163 controls (pooled risk ratio of 1.11 [1.04-1.19], p = 0.003).Conclusion: FIR therapy may positively influence the complex process of AVF maturation improving both primary and secondary patency rates. However blinded RCTs performed by investigators with no commercial ties to FIR therapy technologies are needed. en_US
dc.language.iso eng en_US
dc.publisher Public Library of Science en_US
dc.relation.ispartofseries PLoS ONE;9, (8), e104931
dc.subject nitric-oxide synthase en_US
dc.subject hemodialysis-patients en_US
dc.subject vascular access en_US
dc.subject thermal therapy en_US
dc.subject intimal hyperplasia en_US
dc.subject outcomes en_US
dc.title Role of far infra-red therapy in dialysis arterio-venous fistula maturation and survival: systematic review and meta-analysis en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.date.updated 2014-12-04T17:59:09Z
dc.description.version PUBLISHED
dc.identifier.doi 10.1371/journal.pone.0104931
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1573099
dc.internal.copyrightchecked Yes
dc.description.status peer-reviewed


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