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Against the onslaught of endemic KPC, the war is being lost on the Irish Front.

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Show simple item record O'Connell, Nuala H. Power, Lorraine Powell, James O'Connor, Ciara Dunne, Colum P. 2014-11-20T12:26:12Z 2014-11-20T12:26:12Z 2014
dc.identifier.citation O Connell, N.H., Power, L., Powell, J., O Connor, C., Dunne, C. (2014) 'Against the onslaught of endemic KPC, the war is being lost on the Irish Front'. Journal Of Hospital Infection, . en_US
dc.description peer-reviewed en_US
dc.description.abstract In the context of the excellent report of successful control of an outbreak of carbapenemase-producing Klebsiella pneumoniae in an Italian neonatal intensive care unit published in this journal (1), we wish to report the consequences of the first outbreak of KPC-producing Kliebsiella in Ireland and how, despite identification of operational factors associated with the incidence and best efforts towards rectifying those, our 410-bed hospital in the West of Ireland is failing to control endemic KPCs. Globally, there is recognition of the significant morbidity and mortality implications associated with emergence of carbapenemase-producing bacteria (2). The resulting vigilance has resulted in enhanced reporting of outbreaks, many being the first of their kind in specific countries (3), and descriptions of molecular studies to determine incidence and transfer of the carbapenemase-encoding blaKPC-harboring IncFIA plasmid between clonal variants (4). With indicative rates of carriage being circa 20%, infection control specialists are reacting with novel techniques for microbiological detection, strategies for prevention of nosocomial transmission, and clinical microbiologists are facing therapeutic challenges related to limited, relatively unproven antimicrobial treatment options. en_US
dc.language.iso eng en_US
dc.publisher Elsevier en_US
dc.relation.ispartofseries Journal of Hospital Infection;87 (4), pp. 247-248
dc.rights This is the author’s version of a work that was accepted for publication in Journal of Hospital Infection. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Journal of Hospital Infection , 87 (4), pp. 247-248, en_US
dc.subject KBC en_US
dc.subject Ireland en_US
dc.title Against the onslaught of endemic KPC, the war is being lost on the Irish Front. en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US 2014-11-20T12:08:17Z
dc.description.version ACCEPTED
dc.identifier.doi 10.1016/j.jhin.2014.05.011
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US
dc.internal.rssid 1564610
dc.internal.copyrightchecked Yes
dc.description.status peer-reviewed

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