With increasing recognition of the importance of mental and substance use disorders for population health and health systems and the potential value of systems-based performance indicators in addressing this issue, we ...

Increasing emergency admissions place significant demands on limited hospital resources. We assessed national practices and resources for initiatives to reduce length of stay (LOS) and thereby improve efficiency of ...

In clinical trials, elevated liver transaminase levels in patients taking lumacaftor/ivacaftor therapy were reported. Our aim was to assess in clinical practice, whether F508del homozygous paediatric CF patients had a ...

Background Staphylococcus aureus bacteraemia (SAB) is associated with relatively high risk of complications and high levels of mortality. Internationally, SAB management guidelines lack consensus and especially so regarding ...

Background Mesenteric manifestations are of pathobiologic relevance in Crohn’s disease. Clarification of mesenteric morphology provides an opportunity to re-appraise their pathogenic significance. Therefore, we examined ...

Background: Molecular techniques have uncovered vast numbers of organisms in the cystic fibrosis (CF) airways, the clinical significance of which is yet to be determined. The aim of this study was to describe and compare ...

Background: Internationally, continuing professional competence (CPC) is an increasingly important issue for all health professionals. With the introduction of the first CPC framework for Emergency Medical Technicians ...

Rapid detection of patients with carbapenem-producing Enterobacteriaceae (CPE) is essential for the prevention of nosocomial cross-transmission, allocation of isolation facilities and to protect patient safety. Here, we ...

Background: Existing literature is mixed as to whether self-directed learning (SDL) delivers improvements in knowledge, skills or attitudes of medical students compared with traditional learning methods. This study aimed ...

Background: Anti-microbial resistance (AMR) is a global threat to public health and antibiotics are often unnecessarily prescribed for acute respiratory tract infections (ARTIs) in general practice. We aimed to investigate why ...