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The impact of adjustment for socioeconomic status on comparisons of cancer incidence between two European countries

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Show simple item record Donnelly, David W. Hegarty, Avril C. Sharp, Linda Carsin, Anne-Elie Deady, Sandra McCluskey, Neil Comber, Harry Gavin, Anna 2014-05-16T13:11:52Z 2014-05-16T13:11:52Z 2013
dc.description peer-reviewed en_US
dc.description.abstract Background. Cancer incidence rates vary considerably between countries and by socioeconomic status (SES). We investigate the impact of SES upon the relative cancer risk in two neighbouring countries. Methods. Data on 229,824 cases for 16 cancers diagnosed in 1995–2007 were extracted from the cancer registries in Northern Ireland (NI) and Republic of Ireland (RoI). Cancers in the two countries were compared using incidence rate ratios (IRRs) adjusted for age and age plus area-based SES. Results. Adjusting for SES in addition to age had a considerable impact on NI/RoI comparisons for cancers strongly related to SES. Before SES adjustment, lung cancer incidence rates were 11% higher for males and 7% higher for females in NI, while after adjustment, the IRR was not statistically significant. Cervical cancer rates were lower in NI than in RoI after adjustment for age (IRR: 0.90 (0.84–0.97)), with this difference increasing after adjustment for SES (IRR: 0.85 (0.79–0.92)). For cancers with a weak or nonexistent relationship to SES, adjustment for SES made little difference to the IRR. Conclusion. Socioeconomic factors explain some international variations but also obscure other crucial differences; thus, adjustment for these factors should not become part of international comparisons en_US
dc.language.iso eng en_US
dc.publisher Hindawi Publishing Corporation en_US
dc.relation.ispartofseries Journal of Cancer Epidemiology;Article ID 612514
dc.subject cancer en_US
dc.subject socioeconomic status en_US
dc.subject SES en_US
dc.subject Northern Ireland en_US
dc.subject Republic of Ireland en_US
dc.title The impact of adjustment for socioeconomic status on comparisons of cancer incidence between two European countries en_US
dc.type info:eu-repo/semantics/article en_US
dc.type.supercollection all_ul_research en_US
dc.type.supercollection ul_published_reviewed en_US
dc.contributor.sponsor Public Health (Agency) Northern Ireland en_US
dc.contributor.sponsor HRB en_US
dc.rights.accessrights info:eu-repo/semantics/openAccess en_US

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