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Browsing Synthesis and Solid State Pharmaceutical Centre by Subject "thermodynamics"

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Browsing Synthesis and Solid State Pharmaceutical Centre by Subject "thermodynamics"

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  • Valavi, Masood (University of Limerick, 2017)
    This study investigated two important thermodynamic parameters of crystallisation: the activity coefficient and solubility. The influence of composition and temperature on the activity coefficient was investigated to provide ...
  • Liu, Jin; Svärd, Michael; Rasmuson, Åke C. (American Chemical Society, 2014)
    The influence of agitation and fluid shear on nucleation of m-hydroxybenzoic acid polymorphs from 1-propanol solution has been investigated through 1160 cooling crystallization experiments. The induction time has been ...
  • Svärd, Michael; Gracin, Sandra; Rasmuson, Åke C. (Elsevier, 2007)
    Vanillin crystals in a saturated aqueous solution disappear and a second liquid phase emerges when the temperature is raised above 51°C. The phenomenon has been investigated with crystallization and equilibration experiments, ...
  • Liu, Jin; Svärd, Michael; Hippen, Perschia; Rasmuson, Åke C. (Elsevier, 2015)
    Two crystal polymorphs of 1,7-bis-(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (curcumin) have been obtained by crystallization from ethanol (EtOH) solution. The polymorphs have been characterized by differential ...
  • Svärd, Michael; Valavi, Masood; Khamar, Dikshitkumar; Kuhs, Manuel; Rasmuson, Åke C. (Elsevier, 2016)
    Melting temperatures and enthalpies of fusion have been determined by differential scanning calorimetry (DSC) for 2 polymorphs of the drug tolbutamide: FIH and FV. Heat capacities have been determined by temperature-modulated ...
  • Watterson, Samuel; Hudson, Sarah P.; Svärd, Michael; Rasmuson, Åke C. (Elsevier, 2014)
    Calorimetric data on the melting of 1-methylethyl 2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropanoate (fenofibrate) and the heat capacity of the solid and the melt have been determined, from which the Gibbs energy, enthalpy ...
  • Mealey, Donal; Svärd, Michael; Rasmuson, Åke C. (Elsevier, 2014)
    The solid-liquid solubility of the thermodynamically stable form I of the drug risperidone has been determined by a gravimetric method in nine pure organic solvents in the temperature range 278.15-323.15 K. The melting ...

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