University of Limerick Institutional Repository

Browsing Synthesis and Solid State Pharmaceutical Centre by Subject "kinetics"

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Browsing Synthesis and Solid State Pharmaceutical Centre by Subject "kinetics"

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  • McTague, Hannah (University of Limerick, 2021)
    In this thesis the nucleation kinetics in three pharmaceutical cocrystal systems has been investigated through induction time experiments, identification of the nucleating solid phase and analysis of the nucleation ...
  • Steendam, René R.E.; Keshavarz, Leila; Blijlevens, Melian A.R.; de Souza, Brian P.; Croker, Denise M.; Frawley, Patrick J. (American Chemical Society, 2018)
    Insight into nucleation kinetics and other nucleation parameters can be obtained from probability distributions of induction time measurements in combination with the classical nucleation theory. In this work, induction ...
  • Frawley, Patrick J.; Mitchell, Niall A; Ó'Ciardha, Clifford Thomás; Hutton, Kieran W (Elsevier, 2012-01-01)
    This work details the estimation of the secondary nucleation kinetics of paracetamol in ethanol solutions for cooling crystallisation processes, by means of isothermal under-seeded batch experiments. A numerical model, ...
  • Liu, Jin; Svärd, Michael; Rasmuson, Åke C. (American Chemical Society, 2014)
    The influence of agitation and fluid shear on nucleation of m-hydroxybenzoic acid polymorphs from 1-propanol solution has been investigated through 1160 cooling crystallization experiments. The induction time has been ...
  • Ó'Ciardha, Clifford Thomás; Hutton, Kieran W; Mitchell, Niall A; Frawley, Patrick J. (American Chemical Society, 2012)
    A population balance incorporating nucleation, growth and agglomeration, solved using quadrature method of moments was coupled with a parameter estimation procedure. The seeded anti-solvent crystallisation of Paracetamol ...

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