Browsing Synthesis and Solid State Pharmaceutical Centre by Subject "formulation"

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Amorphous solid dispersions of BCS class II drugs: a rational approach to solvent and polymer selection

Davis, Mark T.; Egan, David P.; Kuhs, Manuel; Albadarin, Ahmad B.; Griffin, Ciara S.; Collins, John A.; Walker, Gavin M. (Elsevier, 2016)

Miniaturised solvent casting (MSC) has been developed as a method for screening the stability of amorphous solid dispersions (ASD) of BCS class II drugs. The aim of the work was to further develop a rapid screening technique ...
Investigation of the particle growth of fenofibrate following antisolvent precipitation and freeze-drying

Tierney, Teresa B.; Guo, Yina; Beloshapkin, Sergey; Rasmuson, Åke C.; Hudson, Sarah P. (American Chemical Society, 2015)

Submicron to small-micron-sized particles of the hydrophobic drug, fenofibrate, were prepared by controlled crystallization in order to influence its dissolution behavior. An antisolvent precipitation process successfully ...
Recent strategies in spray drying for the enhanced bioavailability of poorly water-soluble drugs

Davis, Mark T.; Walker, Gavin M. (Elsevier, 2018)

Poorly water-soluble drugs are a significant and ongoing issue for the pharmaceutical industry. An overview of recent developments for the preparation of spray-dried delivery systems is presented. Examples include amorphous ...

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