Browsing Synthesis and Solid State Pharmaceutical Centre by Subject "caffeine"

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Enabling cocrystallization of challenging systems: passing through a stable cocrystal solvate as a pathway to strenuous cocrystal forms

de Maere d'Aertrycke, J.B.; Payen, R.; Collard, L.; Robeyns, K.; Croker, Denise M.; Leyssens, T. (American Chemical Society, 2020)

Caffeine and maleic acid can form various cocrystal forms, which is a potential route to avoiding hydration issues of caffeine. This particular system was intensively studied as it not only shows cocrystal polymorphism but ...
Spontaneous solid-state co-crystallization of caffeine and urea

MacFhionnghaile, Pól; Crowley, Clare M.; McArdle, Patrick; Erxleben, Andrea (American Chemical Society, 2020)

The co-crystallization of caffeine and urea was monitored and analyzed using infrared spectroscopy, Raman microscopy, scanning electron microscopy, differential scanning calorimetry and X-ray diffraction. The caffeine-urea ...

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