Browsing Synthesis and Solid State Pharmaceutical Centre by Author "Verma, Vivek"

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Crystal growth kinetics of a metastable polymorph of tolbutamide in organic solvents

Soto, Rodrigo; Verma, Vivek; Rasmuson, Åke C. (American Chemical Society, 2020)

The crystal growth of tolbutamide (Form IL) in different solvents has been investigated by isothermal seeded desupersaturation experiments at different temperatures (268-283 K). Experimental data has been evaluated ...
Experimental study on the influence of excipients on the heterogeneous crystallization and dissolution properties of an active pharmaceutical ingredient

Verma, Vivek; Peddapatla, Raghu V.G.; Crowley, Clare M.; Crean, Abina M.; Davern, Peter; Hudson, Sarah P.; Hodnett, Benjamin K. (American Chemical Society, 2018)

This study is based on the heterogeneous nucleation of active pharmaceutical ingredients (APIs) in the presence of various excipients widely used in the pharmaceutical industry. Carbamazepine (CBMZ) was successfully ...
Overcoming the common ion effect for weakly basic drugs: inhibiting the crystallization of clofazimine hydrochloride in simulated gastrointestinal media

Bannigan, Pauric; Verma, Vivek; Hudson, Sarah P. (American Chemical Society, 2019)

Bile salts, phospholipids, and digestive proteins are amphipathic compounds found naturally in the human gastrointestinal system. Therefore, it is important to consider their effects on the crystallization kinetics and ...

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