Biological piezoelectric materials are beginning to gain attention for their huge potential as eco-friendly energy harvesting materials. In particular, simple amino acid and peptide crystal assemblies are demonstrating ...

Different Artificial Neural Network models have been developed and examined for prediction of cocrystal properties based on pure component physical properties only. From the molecular weight, melting temperature, melting ...

Crystallization phenomena in stirred reactors are influenced by local hydrodynamic conditions and these must be taken into account for successful process scale-up and optimization. This article is the first of two presenting ...

Nanoparticles of poorly water-soluble drugs were prepared in suspension via antisolvent precipitation in order to improve their dissolution behaviour. Insoluble, surface-functionalized, micron-range, clay carrier particles ...

Diffraction and spectroscopic methods were evaluated for quantitative analysis of binary powder mixtures of FII(6.403) and FIII(6.525) Piracetam. The two polymorphs of Piracetam could be distinguished using powder X-ray ...

Originally discovered almost a century ago, cocrystals continue to gain interest in the modern day due to their ability to modify the physical properties of solid-state materials, particularly pharmaceuticals. Intensification ...

The crystal growth kinetics of two different polymorphs of Piracetam have been investigated in ethanol and isopropanol. Isothermal seeded desupersaturation experiments were carried out at supersaturation ratios below 1.2 ...

In this thesis the nucleation kinetics in three pharmaceutical cocrystal systems has been investigated through induction time experiments, identification of the nucleating solid phase and analysis of the nucleation ...

The mechanical properties of crystalline materials are crucial knowledge for their screening, design, and exploitation. Density functional theory (DFT), remains one of the most effective computational tools for quantitatively ...

The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus® polymers for enhanced physicochemical stability and solubility of the produced amorphous ...