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Browsing Synthesis and Solid State Pharmaceutical Centre by Author "Moroney, Kevin M."

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Browsing Synthesis and Solid State Pharmaceutical Centre by Author "Moroney, Kevin M."

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  • Castro-Dominguez, Bernardo; Moroney, Kevin M.; Schaller, Barbara E.; O'Connor, S.; Cloonan, Aidan J.; Vo, Tuoi T.N.; Walker, Gavin M.; O'Reilly, Emmet J. (Royal Society of Chemistry, 2017)
    The development of biocompatible membrane materials capable of delivering active pharmaceutical ingredients (APIs) over a fixed time period offers significant advantages to the pharmaceutical and biomedical industries ...
  • Moroney, Kevin M.; Vynnycky, Michael (Elsevier, 2021)
    Understanding drug release from pharmaceutical granules is vital to the development of targeted release profiles. A model describing diffusion and solubility-limited drug dissolu tion and release from a porous spherical ...
  • Moroney, Kevin M.; Kotamarthy, Lalith; Muthancheri, Indu; Ramachandran, Rohit; Vynnycky, Michael (Elsevier, 2021)
    Accurate mechanistic in vitro dissolution models can deliver insight into drug release behaviour and guide formulation development. Drug release profiles from drug-excipient granules can be impacted by variation of porosity ...
  • Schaller, Barbara E.; Moroney, Kevin M.; Castro-Dominguez, Bernardo; Cronin, Patrick; Belen-Girona, Jorge; Ruane, Patrick; Croker, Denise M.; Walker, Gavin M. (Elsevier, 2019)
    In this work, the transfer of oral solid dosage forms, currently manufactured via wet granulation, to a continuous direct compression process was considered. Two main challenges were addressed: (1) a poorly flowing API ...

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