University of Limerick Institutional Repository

Browsing Graduate Entry Medical School by Author "Irish Cancer Society"

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Browsing Graduate Entry Medical School by Author "Irish Cancer Society"

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  • Hayes, Christopher J.; Dowling, Catríona M.; Dwane, Susan; McCumiskey, Mary E.; Tormey, Shona M.; Merrigan, Anne; Coffey, John C.; Kiely, Patrick A.; Dalton, Tara (AIP Publishing, 2016)
    In cancer, biomarkers have many potential applications including generation of a differential diagnosis, prediction of response to treatment, and monitoring disease progression. Many molecular biomarkers have been put ...
  • Dowling, Catríona M.; Phelan, James L.; Callender, Julia A.; Cathcart, Mary Clare; Mehigan, Brian; McCormick, Paul; Dalton, Tara; Coffey, John C.; Newton, Alexandra C.; O'Sullivan, Jacintha; Kiely, Patrick A. (Impact Journals, 2016)
    Despite extensive efforts, cancer therapies directed at the Protein Kinase C (PKC) family of serine/threonine kinases have failed in clinical trials. These therapies have been directed at inhibiting PKC and have, in some ...
  • Kiely, Maeve; Adams, David R.; Hayes, Sheri L.; O'Connor, Rosemary; Baillie, George S.; Kiely, Patrick A. (Elsevier, 2017)
    Conflicting reports implicate the scaffolding protein RACK1 in the progression of breast cancer. RACK1 has been identified as a key regulator downstream of growth factor and adhesion signalling and as a direct binding ...

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