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Browsing Bernal Institute by Author "Zeglinski, Jacek"

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Browsing Bernal Institute by Author "Zeglinski, Jacek"

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  • Zeglinski, Jacek; Svärd, Michael; Karpinska, Jolanta; Kuhs, Manuel; Rasmuson, Åke C. (Elsevier, 2014)
    In this paper we have explored the relationship between surface structure and crystal growth and morphology of fenoxycarb (FC). Experimental vs. predicted morphologies/face indices of fenoxycarb crystals are presented. ...
  • Zeglinski, Jacek; Kuhs, Manuel; Khamar, Dikshitkumar; Hegarty, Avril C.; Devi, Renuka K.; Rasmuson, Åke C. (Wiley and Sons Ltd, 2018)
    The influence of the solvent in nucleation of tolbutamide, a medium-sized, flexible and polymorphic organic molecule, has been explored by measuring nucleation induction times, estimating solvent-solute interaction ...
  • Verma, Vivek; Zeglinski, Jacek; Hudson, Sarah P.; Davern, Peter; Hodnett, Benjamin K. (American Chemical Society, 2018)
    The crystallization of seven active pharmaceutical ingredients (APIs) (acetaminophen (AAP), carbamazepine (CBMZ), caffeine (CAF), phenylbutazone (PBZ), risperidone (RIS), clozapine base (CPB), and fenofibrate (FF)) was ...
  • Kuhs, Manuel; Zeglinski, Jacek; Rasmuson, Åke C. (American Chemical Society, 2014)
    Nearly 1800 induction time experiments have been performed on crystal nucleation of fenoxycarb in isopropanol to investigate the influence of solution pretreatment. For each preheating temperature and preheating time, ...
  • Mealey, Donal; Zeglinski, Jacek; Khamar, Dikshitkumar; Rasmuson, Åke C. (Royal Society of Chemistry, 2015)
    Over 2100 induction time experiments were carried out for the medium-sized, antipsychotic drug molecule, risperidone in seven different organic solvents. To reach the same induction time the required driving force increases ...
  • Heffernan, Claire; Ukrainczyk, Marko; Zeglinski, Jacek; Hodnett, Benjamin K.; Rasmuson, Åke C. (American Chemical Society, 2018)
    In this work, the influence of the structurally related impurities, Demethoxycurcumin (DMC) and Bisdemethoxycurcumin (BDMC) on the primary nucleation of Curcumin (CUR) has been investigated in propan-2-ol. The induction ...
  • Darwish, Shaza; Zeglinski, Jacek; Gamidi, Rama Krishna; Shaikh, Rahamatullah; Khraisheh, Majeda; Walker, Gavin M.; Croker, Denise M. (American Chemical Society, 2018)
    A new 1:1 drug-drug cocrystal of theophylline (THP) and aspirin (ASP) was successfully prepared by liquid assisted grinding, evaporative crystallization and slurry conversion crystallization. The obtained cocrystal was ...
  • Zeglinski, Jacek; Kuhs, Manuel; Devi, Renuka K.; Khamar, Dikshitkumar; Hegarty, Avril C.; Thompson, Damien; Rasmuson, Åke C. (American Chemical Society, 2019)
    Induction time experiments, spectroscopic and calorimetric analysis, and molecular modelling were used to probe the influence of solvent on the crystal nucleation of fenoxycarb (FC), a medium-sized, flexible organic ...
  • Svärd, Michael; Devi, Renuka K.; Khamar, Dikshitkumar; Mealey, Donal; Cheuk, Dominic; Zeglinski, Jacek; Rasmuson, Åke C. (Royal Society of Chemistry, 2018)
    Molecular clustering and solvent–solute interactions in isopropanol solutions of fenoxycarb have been thoroughly and systematically investigated by dynamic light scattering, small-angle X-ray scattering, and nanoparticle ...
  • Prokopowicz, Magdalena; Zeglinski, Jacek; Szewczyk, Adrian; Skwira, Adrianna; Walker, Gavin M. (Springer, 2019)
    Here, we report an inorganic hexagonally ordered mesoporous fibre-like carrier made of silica as an effective drug delivery system with mineralisation potential. Fibre-like SBA-15 has been modified by employing a simple ...

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