Browsing Centres Science and Engineering by Author "Hutton, Kieran W"

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The effects of supersaturation, temperature, agitation and seed surface area on secondary nucleation

Frawley, Patrick J.; Mitchell, Niall A; Ó'Ciardha, Clifford Thomás; Hutton, Kieran W (Elsevier, 2012-01-01)

This work details the estimation of the secondary nucleation kinetics of paracetamol in ethanol solutions for cooling crystallisation processes, by means of isothermal under-seeded batch experiments. A numerical model, ...
Particle size distribution reconstruction: the moment surface method

Hutton, Kieran W; Mitchell, Niall A; Frawley, Patrick J. (Elsevier, 2012)

Numerical simulation of typical chemical engineering processes, such as crystallisation, liquid-liquid extraction, milling and other multi-phase operations in which exist discrete and continuous phases are highly computationally ...
Simultaneous parameter estimation and optimisation of a seeded anti-solvent crystallisation

Ó'Ciardha, Clifford Thomás; Hutton, Kieran W; Mitchell, Niall A; Frawley, Patrick J. (American Chemical Society, 2012)

A population balance incorporating nucleation, growth and agglomeration, solved using quadrature method of moments was coupled with a parameter estimation procedure. The seeded anti-solvent crystallisation of Paracetamol ...

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