Browsing Centres Science and Engineering by Author "Ó'Ciardha, Clifford Thomás"

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The effects of supersaturation, temperature, agitation and seed surface area on secondary nucleation

Frawley, Patrick J.; Mitchell, Niall A; Ó'Ciardha, Clifford Thomás; Hutton, Kieran W (Elsevier, 2012-01-01)

This work details the estimation of the secondary nucleation kinetics of paracetamol in ethanol solutions for cooling crystallisation processes, by means of isothermal under-seeded batch experiments. A numerical model, ...
Numerical modelling of crystallisation processes: kinetics to optimization

Ó'Ciardha, Clifford Thomás (University of Limerick, 2013)

Crystallisation and precipitation processes are used in the chemical and pharmaceutical industry to produce crystals with desired product properties, such as flow ability, filterability, drying time and bioavailability. ...
Simultaneous parameter estimation and optimisation of a seeded anti-solvent crystallisation

Ó'Ciardha, Clifford Thomás; Hutton, Kieran W; Mitchell, Niall A; Frawley, Patrick J. (American Chemical Society, 2012)

A population balance incorporating nucleation, growth and agglomeration, solved using quadrature method of moments was coupled with a parameter estimation procedure. The seeded anti-solvent crystallisation of Paracetamol ...

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