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Browsing Mathematics & Statistics by Author "Walsh, Cathal Dominic"

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Browsing Mathematics & Statistics by Author "Walsh, Cathal Dominic"

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  • Sinnott, Margaret; Kinsley, Brendan T; Jackson, Abaigeal D; Walsh, Cathal Dominic; O'Grady, Tony; Nolan, John J; Gaffney, Peter; Boran, Gerard; Kelleher, Cecily C.; Carr, Bernadette (Public Library of Science, 2015)
    Type 2 diabetes has a long pre clinical asymptomatic phase. Early detection may delay or arrest disease progression. The Diabetes Mellitus and Vascular health initiative (DMVhi) was initiated as a prospective longitudinal ...
  • Romero-Ortuno, Roman; Walsh, Cathal Dominic; Lawlor, Brian A; Kenny, Rose Anne (BioMed Central, 2010)
    Background: A frailty paradigm would be useful in primary care to identify older people at risk, but appropriate metrics at that level are lacking. We created and validated a simple instrument for frailty screening in ...
  • Kieran, Jennifer Ann; Norris, Suzanne; O'Leary, Aisling; Walsh, Cathal Dominic; Merriman, Raphael; Houlihan, D.; McCormick, Aiden; McKiernan, Susan; Bergin, Colm; Barry, Michael (BioMed Central, 2015)
    Background: Recent advances in Hepatitis C therapeutics offer the possibility of cure but will be expensive. The cost of treatment may be partially offset by the avoidance of advanced liver disease. We performed a micro-costing ...
  • Nic Suibhne, Treasa; Raftery, Tara C; McMahon, Orla; Walsh, Cathal Dominic; O'Morain, Colm; O'Sullivan, Maria (Elsevier, 2013)
    Obesity and overweight are major public health issues. Although traditionally associated with weight loss, there is now evidence that increasing Body Mass Index (BMI) and overweight are emerging features of Crohn's disease ...
  • Leahy, Joe; O'Leary, Aisling; Afdhal, Nezam; Gray, Emma; Milligan, Scott; Wehmeyer, Malte H.; Walsh, Cathal Dominic (Wiley and Sons Ltd, 2018)
    The use of individual patient data (IPD) in network meta-analysis (NMA) is becoming increasingly popular. However, as most studies do not report IPD, most NMAs are performed using aggregate data for at least some, if not ...
  • Leahy, Joe; Thom, Howard; Jansen, Jeroen P; Gray, Emma; O'Leary, Aisling; White, Arthur; Walsh, Cathal Dominic (Wiley and Sons Ltd, 2019)
    Increasingly, single-armed evidence is included in health technology assessment submissions when companies are seeking reimbursement for new drugs. While it is recognized that randomized controlled trials provide a higher ...
  • Batten, Isabella; Robinson, Mark W.; White, Arthur; Walsh, Cathal Dominic; Fazekas, Barbara; Wyse, Jason; Buettner, Antonia; D’Arcy, Suzanne; Greenan, Emily; Murphy, Conor C.; Wigston, Zoe; Ní Gabhann‑Dromgoole, Joan; Vital, Edward M.; Little, Mark A.; Bourke, Nollaig M. (Nature, 2021)
    Type I interferon (IFN) dysregulation is a major contributory factor in the development of several autoimmune diseases, termed type I interferonopathies, and is thought to be the pathogenic link with chronic infammation ...
  • Walsh, Cathal Dominic (Univerza v Ljubljani, Fakulteta za Druzbene Vede, 2006)
    Latent variable models have been used extensively in the social sciences. In this work a latent class analysis is used to identify syndromes within Alzheimer's disease. The fitting of the model is done in a Bayesian framework, ...
  • Lynch, Julie; Prihodova, Lucia; Dunne, Pádraic J.; O'Leary, Caoimhe; Breen, Rachel; Carroll, Áine; Walsh, Cathal Dominic; McMahon, Geraldine; White, Barry (BMJ Publishing Group, 2018)
    Objectives Rates of burnout and stress in healthcare practitioners are steadily increasing. Emergency department (ED) staff are particularly susceptible to such poor outcomes. Mantra meditation (MM) may contribute to ...
  • Garvey, Marie; Lyons, Rachel; Hector, Ralph D.; Walsh, Cathal Dominic; Arkins, Sean; Cullinane, Ann (MDPI, 2019)
    Multiple locus typing based on sequencing heterologous regions in 26 open reading frames (ORFs) of equine herpesvirus 1 (EHV-1) strains Ab4 and V592 was used to characterise 272 EHV-1 isolates from 238 outbreaks of abortion, ...
  • Ndukwe, Ihedinachi; O'Riordan, Sean; Walsh, Cathal Dominic; Hutchinson, Michael (Elsevier, 2020)
    Mood disorder is common in cervical dystonia, affects quality of life and may precede the onset of the dystonia. There is controversy as to whether mood disorder is part of the primary process or secondary to the disability. ...
  • Gildea, Sarah; Garvey, Marie; Lyons, Pamela; Lyons, Rachel; Gahan, Jacinta; Walsh, Cathal Dominic; Cullinane, Ann (MDPI, 2018)
    Equine influenza (EI) outbreaks occurred on 19 premises in Ireland during 2014. Disease affected thoroughbred (TB) and non-TB horses/ponies on a variety of premises including four racing yards. Initial clinical signs ...
  • Lawlor, Brian; Kennelly, Sean; O'Dwyer, Sarah; Cregg, Fiona; Walsh, Cathal Dominic; Cohen, Robert; Kenny, Rose Anne; Howard, Robert; Murphy, Caroline; Adams, Jessica; Daly, Leslie; Segurado, Ricardo; Gaynor, Siobhan; Crawford, Fiona; Mullan, Michael; Lucca, Ugo; Banzi, Rita; Pasquier, Florence; Breuilh, Laetitia; Riepe, Matthias W.; Kalman, Janos; Wallin, Anders; Borjesson-Hanson, Anne; Molloy, William; Tsolaki, Magda; Rikkert, Marcel Olde (BMJ Publshing Group, 2014)
    This study is a European multicentre, randomised, double-blind, placebo-controlled trial investigating the efficacy and safety of nilvadipine as a disease course modifying treatment for mild-tomoderate Alzheimer’s ...
  • Lawlor, Brian; Segurado, Ricardo; Kennelly, Sean; Olde Rikkert, Marcel G. M.; Howard, Robert; Pasquier, Florence; Borjesson-Hanson, Anne; Tsolaki, Magda; Lucca, Ugo; Molloy, D. William; Coen, Robert; Riepe, Matthias W.; Kálmán, János; Kenny, Rose Anne; Cregg, Fiona; O'Dwyer, Sarah; Walsh, Cathal Dominic; Adams, Jessica; Banzi, Rita; Breuilh, Laetitia; Daly, Leslie; Hendrix, Suzanne; Aisen, Paul; Gaynor, Siobhan; Sheikhi, Ali; Taekema, Diana G.; Verhey, Frans R.; Nemni, Raffaello; Nobili, Flavio; Franceschi, Massimo; Frisoni, Giovanni; Zanetti, Orazio; Konsta, Anastasia; Anastasios, Orologas; Nenopoulou, Styliani; Tsolaki-Tagaraki, Fani; Pakaski, Magdolna; Dereeper, Olivier; de la Sayette, Vincent; Sénéchal, Olivier; Lavenu, Isabelle; Devendeville, Agnés; Calais, Gauthier; Crawford, Fiona; Mullan, Michael (Public Library of Science, 2018)
    Background This study reports the findings of the first large-scale Phase III investigator-driven clinical trial to slow the rate of cognitive decline in Alzheimer disease with a dihydropyridine (DHP) calcium channel ...
  • McAloon, Conor G.; Wall, Patrick; Butler, Francis; Codd, Mary; Gormley, Eamonn; Walsh, Cathal Dominic; Duggan, Jim; Murphy, Brendan T.; Nolan, Philip; Smyth, Breda; O'Brien, Katie; Teljeur, Conor; Green, Martin J.; O'Grady, Luke; Culhane, Kieran; Buckley, Claire; Carroll, Ciara; Doyle, Sarah; Martin, Jennifer; More, Simon J. (BMC, 2021)
    Background: Contact tracing is conducted with the primary purpose of interrupting transmission from individuals who are likely to be infectious to others. Secondary analyses of data on the numbers of close contacts of ...
  • Tuite, H.; Horgan, Mary; Mallon, P.W.G.; McConkey, S.J.; Mooka, B.; Mulcahy, F.; Walsh, Cathal Dominic; O'Hora, A.; O'Flanagan, Darina; Bergin, Colm; Fleming, C. (Irish Medical Organisation, 2015)
    This study describes the demographics and treatment status of HIV-infected adults accessing ambulatory care in the Republic of Ireland and estimates diagnosed HIV prevalence rates. 3254 HIV-infected adults attended 1 of ...
  • O'Rourke, Killian; Berge, E.; Walsh, Cathal Dominic; Kelly, P.J. (The Cochrane Collaboration. Published by John Wiley & Sons, Ltd, 2010)
    Most disabling strokes are due to blockage of a large artery in the brain by a blood clot. Prompt removal of the clot with intra-arterial thrombolytic drugs or mechanical devices, or both, can restore blood flow before ...
  • Brisson, Marc; Bénard, Élodie; Drolet, Melanie; Bogaards, Johannes A.; Baussano, Iacopo; Vänskä, Simopekka; Jit, Mark; Boily, Marie-Claude; Smith, Megan A.; Berkhof, Johannes; Canfell, Karen; Chesson, Harrell W.; Burger, Emily A.; Choi, Yoon H.; De Blasio, Birgitte Freiesleben; De Vlas, Sake J.; Guzzetta, Giorgio; Hontelez, Jan A. C.; Horn, Johannes; Jepsen, Martin R.; Kim, Jane J.; Lazzarato, Fulvio; Matthijsse, Suzette M.; Mikolajczyk, Rafael; Pavelyev, Andrew; Pillsbury, Matthew; Shafer, Leigh Anne; Tully, Stephen P.; Turner, Hugo C.; Usher, Cara; Walsh, Cathal Dominic (Elsevier, 2016)
    Background Modelling studies have been widely used to inform human papillomavirus (HPV) vaccination policy decisions; however, many models exist and it is not known whether they produce consistent predictions of population-level ...
  • O'Neill, Aoife (University of Limerick, 2019)
    Identifying subgroups within a population can provide important insights to decision makers. When concerned with health data, identifying profiles of individuals who share similar characteristics may inform targeted ...
  • Sharp, Linda; Walsh, Cathal Dominic; Whyte, Sophie; Tilson, Lesley; O'Ceilleachair, Alan; Usher, Cara; Tappenden, Paul; Chilcott, James; Staines, Anthony; Barry, Michael; Comber, Harry (Nature Publishing Group, 2013)
    In his letter, Dr O’Mahony (2012) makes two main points. The first of these relates to the number of alternatives explored during our assessment of colorectal cancer screening in Ireland (Sharp et al, 2012), and the ...

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