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A finite element analysis rupture index (FEARI) as an additional tool for abdominal aortic aneurysm rupture prediction

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Show simple item record McGloughlin, Timothy M. Doyle, Barry J. Callanan, Anthony Walsh, Michael T. Grace, Pierce A. 2009-08-18T09:34:48Z 2009-08-18T09:34:48Z 2009
dc.description Peer-reviewed
dc.description.abstract Currently, abdominal aortic aneurysms (AAAs), which are a permanent dilation of the aorta, are treated surgically when the maximum transverse diameter surpasses 5.5cm. AAA rupture occurs when the locally acting wall stress exceeds the locally acting wall strength. There is a need to review the current diameter-based criterion, and so it may be clinically useful to develop an additional tool to aid the surgical decision-making process. A Finite Element Analysis Rupture Index (FEARI) was developed. Ten patient-specific AAAs were reconstructed, and the corresponding wall stress computed. Previous experimental work on determination of ultimate tensile strengths (UTS) from AAA tissue samples was implemented in this study. By combining peak wall stress along with average regional UTS, a new approach to the estimation of patient-specific rupture risk has been developed. Ten cases were studied, all of which were awaiting or had previously undergone surgical AAA repair. A detailed examination of these ten cases utilising the FEARI analysis suggested that there was a possibility that some of the AAAs may have been less prone to rupture than previously considered. It is proposed that FEARI, used alongside other rupture risk factors, may improve the current surgical decision-making process. The use of FEARI as an additional tool for rupture prediction may provide a useful adjunct to the diameter-based approach in surgical decision-making. en
dc.language.iso eng en
dc.publisher Bentham Science Publishers en
dc.relation.ispartofseries Vascular Disease Prevention;Vol. 6/ pp. 114-121
dc.subject aneurysm en
dc.subject rupture en
dc.title A finite element analysis rupture index (FEARI) as an additional tool for abdominal aortic aneurysm rupture prediction en
dc.type Journal Article en
dc.type.supercollection all_ul_research en
dc.type.supercollection ul_published_reviewed
dc.type.restriction none en
dc.contributor.sponsor US National Heart Lung and Blood Institute
dc.contributor.sponsor IRCSET
dc.relation.projectid R01-HL-060670
dc.relation.projectid RS/2005/340

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