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Browsing Mechanical, Aeronautical & Biomedical Engineering by Title

Browsing Mechanical, Aeronautical & Biomedical Engineering by Title

Now showing items 10-29 of 180

Biomechanical and computational investigation of the hip protector design and function

Madrecka, Aleksandra (University of Limerick, 2012)

and related hip fracture in the elderly population are a serious problem in health care. It is widely documented that prevention of hip fracture has the potential to improve the quality of life and substantially decrease ...
BOJCAS: Bolted joints in composite aircraft structures

McCarthy, Michael A. (University of Limerick, 2003)

The objective of BOJCAS was to develop advanced design methods for bolted joints in composite aircraft structures. This is a critical technology supporting the introduction of composites into the primary structure of ...
Cell-seeded decellularised extracellular matrices as an advanced approach for tissue engineering

Piterina, Anna Valentinova; Davis, Laura M.; Meaney, Claire L.; Cloonan, Aidan J.; Walsh, Michael T.; McGloughlin, Timothy M. (2009)

Development and optimisation of therapeutic applications using biological scaffolds composed of naturally occurring extracellular matrix (ECM) have received significant attention in the field of tissue engineering. ...
Characterisation of head-hardened rail steel in terms of cyclic plasticity response and microstructure for improved material modelling

Athukorala, Asitha C; De Pellegrin, Dennis V.; Kourousis, Kyriakos I. (Elsevier, 2016)

Stress- and strain-controlled tests of heat treated high-strength rail steel (Australian Standard AS1085.1) have been performed in order to improve the characterisation of the said material׳s ratcheting and fatigue wear ...
Characterisation of the fundamental function(s) of bovine serum albumin in the culture of NS0 cells

McNamara, Liam (University of Limerick, 2016)

The large-scale production of therapeutic monoclonal antibodies (mAbs) is commonly carried out using NS0 cells, which are a cholesterol deficient mouse myeloma cell line. The non-ionic surfactant Pluronic F-68 is routinely ...
Characterising human atherosclerotic carotid plaque tissue composition and morphology using combined spectroscopic and imaging modalities

Barrett, Hilary E; Mulvihill, John J.; Cunnane, Eoghan M; Walsh, Michael T. (BioMed Central, 2015)

Calcification is a marked pathological component in carotid artery plaque. Studies have suggested that calcification may induce regions of high stress concentrations therefore increasing the potential for rupture. However, ...
The characterization of obstructed laminar channel flows for local heat transfer enhancement in microfluidic cooling applications

Waddell, Alistair Martin (University of Limerick, 2015)

Some of the largest heat fluxes that can be found in contemporary engineering applications (O ∼ 10^3 W/cm2) are generated by laser-bar arrays within Photonics Integrated Circuits (PICs) – the backbone of optical telecommunication ...
Comparing the endothelialisation of extracellular matrix bioscaffolds with coated synthetic vascular graft materials

Coakley, Daniel Nicholas Martin; Shaikh, F.M; O'Sullivan, K; Kavanagh, Eamon G; Grace, P.A; Walsh, S.R; McGloughlin, Timothy M. (Elsevier, 2016)

Introduction Existing synthetic vascular grafts have unacceptably high failure rates when replacing small diameter infrapopliteal vessels [1]. The lack of a confluent endothelial lining is repeatedly cited as the most ...
A comparison of modelling techniques for computing wall stress in abdominal aortic aneurysms

Doyle, Barry J.; Callanan, Anthony; McGloughlin, Timothy M. (BioMed Central, 2007)

BACKGROUND: Aneurysms, in particular abdominal aortic aneurysms (AAA), form a significant portion of cardiovascular related deaths. There is much debate as to the most suitable tool for rupture prediction and interventional ...
Comparison of open hole tension characteristics of high strength glass and carbon fibre-reinforced composite materials

O'Higgins, Ronan M.; McCarthy, Michael A.; McCarthy, Conor T. (Elsevier, 2008)

An experimental study was carried out to determine the open hole tension (OHT) characteristics of carbon fibre-reinforced plastic (CFRP) and high strength S2-glass fibre-reinforced plastic (GFRP). Tests to failure and ...
Computational modelling of energy absorption characteristics of epoxy/CNT nanocomposites

Weidt, David (University of Limerick, 2014)

Epoxy-based composite laminates frequently behave as brittle materials under various types of loading, from quasi-static to impact, as they cannot absorb/dissipate enough energy. Matrix cracks develop due to the brittle ...
Constitutive modeling of additive manufactured Ti-6Al-4V cyclic elastoplastic behaviour

Kourousis, Kyriakos I.; Agius, Dylan J.; Wang, Chun; Subic, Aleksandar (Otto von Guericke Universitaet * Institut fuer Mechanik, 2016)

Metal additive manufacturing techniques have been increasingly attracting the interest of the aerospace and biomedical industry. A particular focus has been on high value and complexity parts and components, as there the ...
Constitutive modeling of Aluminum Alloy 7050 cyclic mean stress relaxation and ratcheting

Kourousis, Kyriakos I.; Dafalias, Yannis F (2013)

The challenge of describing in a generalized mathematical pattern the inelastic behavior of metals has led to the development of several constitutive models, especially in the field of cyclic plasticity, where phenomena ...
Continuous flow digital PCR for absolute quantification of nucleic acids

Dalton, Mark A (University of Limerick, 2012)

Digital polymerase chain reaction (PCR) has emerged as an extremely powerful technique for quantification of nucleic acids. Digital PCR offers superior quantification accuracy, precision and sensitivity compared to ...
Cyclic plasticity model with multiplicative backstress decomposition

Kourousis, Kyriakos I.; Saridis, G.J; Dafalias, Yannis F (Transworld Research Network, 2007)

The challenge of developing a generalized mathematical pattern to describe the plastic behaviour of metals, lead researchers to propose various constitutive models, especially in the field of cyclic plasticity, where ...
Damage modelling of fibre reinforced polymer matrix composite open hole tension specimens using the Ladevèze damage model in Pam-CRASH

O'Higgins, Ronan M.; McCarthy, Michael A. (2005)

The goal of this project was to accurately predict the ultimate failure strengths of fibre reinforced polymer matrix composite open hole tension specimens using the Ladevèze continuum mechanics damage model, currently ...
Deformation of the lamina cribrosa and optic nerve due to changes in cerebrospinal fluid pressure

Feola, Andrew J.; Coudrillier, Baptiste; Mulvihill, John J.; Geraldes, Diogo M.; Vo, Nghia T.; Albon, Julie; Abel, Richard L.; Samuels, Brian C.; Ross Ethier, C. (Association for Research in Vision and Ophthalmology, 2017)

PURPOSE. Cerebrospinal fluid pressure (CSFp) changes are involved or implicated in various ocular conditions including glaucoma, idiopathic intracranial hypertension, and visual impairment and intracranial pressure syndrome. ...
Design and characterisation of a micro-flow cytometer with 3D hydrodynamic focusing

Chiavaroli, Stefano (University of Limerick, 2011)

Recent advances in micro fabrication technology have resulted in proliferation of microscale mechanical devices, most of which are applied in the biomedical field and clinical diagnostics. One of the most promising ...
Design and optimisation of the impulse turbine with an internal variable-pitch controlled guide vane system using computational fluid dynamics and experimental analysis

Cashman, Patrick Andrew (University of Limerick, 2012)

Following a review of previous research on wave power conversion, it is evident that Oscillating Water Columns are one of the few devices to successfully convert wave power to electrical power at a commercial stage. ...
Design, optimization and manufacturing of a unitized carbon fiber/thermoplastic wingbox structure

Oliveri, Vincenzo; Peeters, Daniël; Clancy, Gearóid J.; Jones, David; O'Higgins, Ronan M.; Weaver, Paul M. (American Institute of Aeronautics and Astronautics: AIAA, 2018)

Manufacture of high performance large composite aerostructures in an out-of-autoclave process using thermoplastic composites that is cost-effective is highly attractive and, at the same time, technologically challenging. ...

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