University of Limerick Institutional Repository

Browsing Biological Sciences by Subject "zinc"

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Browsing Biological Sciences by Subject "zinc"

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  • De Benedictis, Chiara A.; Raab, Andrea; Ducie, Ellen; Howley, Shauna; Feldmann, Joerg; Grabrucker, Andreas M. (MDPI, 2020)
    The essential trace metals iron, zinc, and copper have a significant physiological role in healthy brain development and function. Especially zinc is important for neurogenesis, synaptogenesis, synaptic transmission and ...
  • Hagmeyer, Simone; Romão, Mariana A.; Cristóvão, Joana S.; Vilella, Antonietta; Zoli, Michele; Gomes, Cláudio M.; Grabrucker, Andreas M. (Frontiers Media, 2019)
    Increasing evidence links proteins of the S100 family to the pathogenesis of Alzheimer’s disease (AD). S100 proteins are EF-hand calcium-binding proteins with intra- and extracellular functions related to regulation of ...
  • De Benedictis, Chiara A.; Vilella, Antonietta; Grabrucker, Andreas M. (2019)
    The extracellular aggregation of insoluble protein deposits of amyloid-β (Aβ) into plaques and the hyperphosphorylation of the intracellular protein tau leading to neurofibrillary tangles are the main pathological hallmarks ...

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