Browsing Biological Sciences by Author "Schellekens, Harriët"

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Milk protein hydrolysates activate 5-HT2C serotonin receptors: influence of the starting substrate and isolation of bioactive fractions

Nongonierma, Alice B.; Schellekens, Harriët; Dinan, Timothy G.; Cryan, John F.; Fitzgerald, Richard J. (Royal Society of Chemistry, 2013)

Milk protein hydrolysates generated with different starting substrates, including sodium caseinate (NaCN), acid casein (Acid CN), skim milk powder (SMP) and glycomacropeptide (GMP) were demonstrated to behave as serotonin ...
Milk protein-derived peptides induce 5-HT2C-mediated satiety,in vivo

Schellekens, Harriët; Nongonierma, Alice B.; Clarke, Gerard; van Oeffelen, Wesley E.P.A.; Fitzgerald, Richard J.; Dinan, Timothy G.; Cryan, John F. (Elsevier, 2014)

This study investigates the ability of milk protein-derived peptides to specifically activate the serotonin 2C (5-HT2C) receptor, a key receptor in central regulation of food intake. A dose dependent 5-HT2C receptor ...

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