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Browsing Biological Sciences by Author "Sarowar, Tasnuva"

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Browsing Biological Sciences by Author "Sarowar, Tasnuva"

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  • Sarowar, Tasnuva; Grabrucker, Andreas M. (Hindawi Publishing Corporation, 2016)
    Shank proteins (Shank1, Shank2, and Shank3) act as scaffolding molecules in the postsynaptic density of many excitatory neurons. Mutations in SHANK genes, in particular SHANK2 and SHANK3, lead to autism spectrum disorders ...
  • Sarowar, Tasnuva; Grabrucker, Stefanie; Föhr, Karl; Mangus, Katharina; Eckert, Matti; Bockmann, Juergen; Boeckers, Tobias M.; Grabrucker, Andreas M. (BioMed Central, 2016)
    The majority of neurons within the central nervous system receive their excitatory inputs via small, actin-rich protrusions called dendritic spines. Spines can undergo rapid morphological alterations according to synaptic ...
  • Sarowar, Tasnuva; Grabrucker, Stefanie; Boeckers, Tobias M.; Grabrucker, Andreas M. (Frontiers Media, 2017)
    RICH2 knockout (RICH2 KO) mice exhibit neophobia in the novel object test. To gain further insight into their anxiety-related phenotype, we subjected these mice to additional behavioral tests to elucidate whether the ...
  • Vilella, Antonietta; Belletti, Daniela; Sauer, Ann Katrin; Hagmeyer, Simone; Sarowar, Tasnuva; Masoni, Martina; Stasiak, Natalia; Mulvihill, John J.E.; Ruozi, Barbara; Forni, Flavio; Vandelli, Maria Angela; Tosi, Giovanni; Zoli, Michele; Grabrucker, Andreas M. (Elsevier, 2017)
    A local dyshomeostasis of zinc ions in the vicinity of amyloid aggregates has been proposed in Alzheimer’s disease (AD) due to the sequestration of zinc in senile plaques. While an increase in zinc levels may promote the ...
  • Sarowar, Tasnuva; Grabrucker, Andreas M. (MDPI, 2020)
    Fear is a fundamental evolutionary process for survival. However, excess or irrational fear hampers normal activity and leads to phobia. The amygdala is the primary brain region associated with fear learning and conditioning. ...

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