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Browsing Biological Sciences by Author "Sahebkar, Amirhossein"

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Browsing Biological Sciences by Author "Sahebkar, Amirhossein"

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  • The complex roles of efferocytosis in cancer development, metastasis, and treatment 
    Tajbakhsh, Amir; hayat, Seyed Mohammad Gheibi; Movahedpour, Ahmad; Savardashtaki, Amir; Loveless, Reid; Barreto, George E.; Teng, Yong; Sahebkar, Amirhossein (Elsevier, 2021)
    When tumor cells are killed by targeted therapy, radiotherapy, or chemotherapy, they trigger their primary tumor by releasing pro-inflammatory cytokines. Microenvironmental interactions can also promote tumor heterogeneity ...
  • Identification of difluorinated curcumin molecular targets linked to traumatic brain injury pathophysiology 
    Sahebkar, Amirhossein; Sathyapalan, Thozhukat; Guest, Paul C.; Barreto, George E. (Elsevier, 2022)
    Traumatic brain injury (TBI) affects approximately 50% of the world population at some point in their lifetime. To date, there are no effective treatments as most of the damage occurs due to secondary effects through a ...
  • In silico interactions of statins with cell death-inducing DNA fragmentation factor-like effector A (CIDEA) 
    Barreto, George E.; Gonzalez, Janneth; Reiner, Zeljko; Jamialahmadi, Tannaz; Echeverria, Valentina; Ashraf, Ghulam; Sahebkar, Amirhossein (Elsevier, 2021)
    Statins are the low-density lipoproteins (LDL)-cholesterol-lowering drugs of first choice and are used to prevent the increased risk of cardiovascular and cerebrovascular diseases. Although some of their effects are well ...
  • Lipotoxicity, neuroinflammation, glial cells and oestrogenic compounds 
    Hidalgo-Lanussa Oscar; Baez-Jurado, Eliana; Echeverria, Valentina; Ashraf, Ghulam; Sahebkar, Amirhossein; Garcia-Segura Luis Miguel; Melcangi, Roberto C.; Barreto, George E. (Wiley and Sons Ltd, 2019)
    The high concentrations of free fatty acids as a consequence of obesity and overweight have become risk factors for the development of different diseases including neurodegenerative ailments. Free fatty acids (FAs) are ...
  • Neuroprotective effects of minocycline on focal cerebral ischemia injury: a systematic review 
    Naderi, Yazdan; Panahi, Yunes; Barreto, George E.; Sahebkar, Amirhossein (Medknow Publications, 2019)
    To review the neuroprotective effects of minocycline in focal cerebral ischemia in animal models. By searching in the databases of PubMed, ScienceDirect, and Scopus, and considering the inclusion and exclusion criteria of ...
  • Phytochemicals as inhibitors of tumor necrosis factor alpha and neuroinflammatory responses in neurodegenerative diseases 
    Zahedipour, Fatemeh; Hosseini, Seyede Atefe; Henney, Neil C.; Barreto, George E.; Sahebkar, Amirhossein (Medknow Publications, 2022)
    Inflammatory processes and proinflammatory cytokines have a key role in the cellular processes of neurodegenerative diseases and are linked to the pathogenesis of functional and mental health disorders. Tumor necrosis ...
  • Potential effects of curcumin in the treatment of COVID-19 infection 
    Zahedipour, Fatemeh; Hosseini, Seyede Atefe; Sathyapalan, Thozhukat; Majeed, Muhammed; Jamialahmadi, Tannaz; Al-Rasadi, Khalid; Banach, Maciej; Sahebkar, Amirhossein (Wiley and Sons Ltd, 2020)
    Coronavirus disease 2019 (COVID-19) outbreak is an ongoing pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with considerable mortality worldwide. The main clinical manifestation of COVID-19 ...
  • The potential of mitochondrial modulation by neuroglobin in treatment of neurological disorders 
    Gorabi, Armita Mahdavi; Aslani, Saeed; Barreto, George E.; Baez-Jurado, Eliana; Kiaie, Nasim; Jamialahmadi, Tannaz; Sahebkar, Amirhossein (Elsevier, 2021)
    Neuroglobin is the third member of the globin family to be identified in 2000 in neurons of both human and mouse nervous systems. Neuroglobin is an oxygen-binding globin found in neurons within the central nervous system ...
  • Resolution of inflammation in neurodegenerative diseases:The role of resolvins 
    Chamani, Sajad; Bianconi, Vanessa; Tasbandi, Aida; Pirro, Matteo; Barreto, George E.; Jamialahmadi, Tannaz; Sahebkar, Amirhossein (Hindawi, 2020)
    Acute inflammation has been described as a reactive dynamic process, promoted by the secretion of proinflammatory mediators, including lipid molecules like leukotrienes and prostaglandins, and counterbalanced by proresolving ...

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