Aims: Present a novel machine learning computational strategy to predict the neuroprotection potential of nicotine analogs acting over the behavior of unpaired signaling pathways in Parkinson's disease. Background: ...

The oak species Quercus petraea and Q. robur are dominant canopy tree species of native deciduous forests in Ireland and coastal regions of Western Europe. These forests are typically plant species-rich, and can also have ...

Breakthrough alternative technologies are urgently required to alleviate the critical need to decarbonise our energy supply. We showcase non-conventional approaches to battery and solar energy conversion and storage (ECS) ...

Metal levels (iron, zinc, manganese, cobalt, chromium, copper and nickel) were determined in Cerastoderma edule, Mytilus edulis, Monodonta lineata, Patella vulgata, Nucella lapillus, Littorina obtusata and L. littorea at ...

Metal dyshomeostasis plays a significant role in various neurological diseases such as Alzheimer’s disease, Parkinson’s disease, Autism Spectrum Disorders (ASD), and many more. Like studies investigating the proteome, ...

Biochar amended soils have demonstrated various agronomic benefits, principally a plant growth promotion effect. The char’s impact, however, on macronutrient bio-availability and the microorganisms involved in their ...

A multifactorial [temperature (40, 50 and 60 °C), hydrolysis time (60, 150 and 240 min) and enzyme to substrate ratio (E:S; 1.0, 1.5 and 2.0%)] design of experiments (DOE) was used to optimise the release of dipeptidyl ...

This study investigates the ability of milk protein-derived peptides to specifically activate the serotonin 2C (5-HT2C) receptor, a key receptor in central regulation of food intake. A dose dependent 5-HT2C receptor ...

Biochar has shown great potentials in plant growth promotion but its effect on soil bacteria that potentially support plant growth is less well understood. In this study, the effect of biochar soil amendment was investigated ...

Mesoporous silicates (MPS) possess ordered pore structures with pore diameters sufficiently large to accommodate a range of enzymes. The successful immobilization of an enzyme on MPS usually requires modification of the ...