Aims: Present a novel machine learning computational strategy to predict the neuroprotection potential of nicotine analogs acting over the behavior of unpaired signaling pathways in Parkinson's disease. Background: ...

Cheese, a product of microbial fermentation may be defined as a protein matrix entrapping fat, moisture, minerals and solutes as well as dispersed bacterial colonies. The growth and physiology of bacterial cells in these ...

Metal levels (iron, zinc, manganese, cobalt, chromium, copper and nickel) were determined in Cerastoderma edule, Mytilus edulis, Monodonta lineata, Patella vulgata, Nucella lapillus, Littorina obtusata and L. littorea at ...

Biochar amended soils have demonstrated various agronomic benefits, principally a plant growth promotion effect. The char’s impact, however, on macronutrient bio-availability and the microorganisms involved in their ...

A multifactorial [temperature (40, 50 and 60 °C), hydrolysis time (60, 150 and 240 min) and enzyme to substrate ratio (E:S; 1.0, 1.5 and 2.0%)] design of experiments (DOE) was used to optimise the release of dipeptidyl ...

This study investigates the ability of milk protein-derived peptides to specifically activate the serotonin 2C (5-HT2C) receptor, a key receptor in central regulation of food intake. A dose dependent 5-HT2C receptor ...

Biochar has shown great potentials in plant growth promotion but its effect on soil bacteria that potentially support plant growth is less well understood. In this study, the effect of biochar soil amendment was investigated ...

Synapses, contact points between neurons, are essential elements supporting the ability of neurons to communicate and to transmit relevant information to each other. They play an integral role in brain development and ...

The objectives of this thesis were: 1) to understand the effect of early calf nutrition on the transcriptome of subcutaneous adipose tissue and their downstream effects on the hypothalamic-pituitary-testicular (HPT) axis ...

Physical loading is a potent regulator of bone anabolism, yet the cellular mechanisms by which this occurs are poorly understood. Due to the finite lifespan of bone forming osteoblasts, it is hypothesized that these cells ...